Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging View Full Text


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Article Info

DATE

2015-09-18

AUTHORS

Gert Klug, Sebastian Johannes Reinstadler, Hans-Josef Feistritzer, Christian Kremser, Johannes P. Schwaiger, Martin Reindl, Johannes Mair, Silvana Müller, Agnes Mayr, Wolfgang-Michael Franz, Bernhard Metzler

ABSTRACT

ObjectivesPhase-contrast CMR (PC-CMR) might provide a fast and robust non-invasive determination of left ventricular function in patients after ST-segment elevation myocardial infarction (STEMI).MethodsCine sequences in the left-ventricular (LV) short-axis and free-breathing, retrospectively gated PC-CMR were performed in 90 patients with first acute STEMI and 15 healthy volunteers. Inter- and intra-observer agreement was determined. The correlations of clinical variables (age, gender, ejection fraction, NT pro-brain natriuretic peptide [NT-proBNP] with cardiac index (CI) were calculated.ResultsFor CI, there was a strong agreement of cine CMR with PC-CMR in healthy volunteers (r: 0.82, mean difference: -0.14 l/min/m2, error ± 23 %). Agreement was lower in STEMI patients (r: 0.61, mean difference: -0.17 l/min/m2, error ± 32 %). In STEMI patients, CI measured with PC-CMR showed lower intra-observer (1 % vs. 9 %) and similar inter-observer variability (9 % vs. 12 %) compared to cine CMR. CI was significantly correlated with age, ejection fraction and NT-proBNP values in STEMI patients.DiscussionThe agreement of PC-CMR and cine CMR for the determination of CI is lower in STEMI patients than in healthy volunteers. After acute STEMI, CI measured with PC-CMR decreases with age, LV ejection fraction and higher NT-proBNP.Key Points• Cine CMR and PC-CMR correlate well in healthy volunteers.• Agreement is lower in STEMI patients.• Cardiac Output should be measured with one method longitudinally.• Cardiac output decreases with age after myocardial infarction. More... »

PAGES

1999-2008

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  • Identifiers

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    http://scigraph.springernature.com/pub.10.1007/s00330-015-4022-7

    DOI

    http://dx.doi.org/10.1007/s00330-015-4022-7

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1049492208

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26385805


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