Granulomatous mastitis: changing clinical and imaging features with image-guided biopsy correlation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-10

AUTHORS

Priyanka Handa, A. Jill Leibman, Derek Sun, Maria Abadi, Aryeh Goldberg

ABSTRACT

OBJECTIVES: To review clinical presentation, revisit patient demographics and imaging findings in granulomatous mastitis and determine the optimal biopsy method for diagnosis. METHODS: A retrospective study was performed to review the clinical presentation, imaging findings and biopsy methods in patients with granulomatous mastitis. Twenty-seven patients with pathology-proven granulomatous mastitis were included. RESULTS: The average age at presentation was 38.0 years (range, 21-73 years). Seven patients were between 48 and 73 years old. Twenty-four patients presented with symptoms and three patients were asymptomatic. Nineteen patients were imaged with mammography demonstrating mammographically occult lesions as the predominant finding. Twenty-six patients were imaged with ultrasound and the most common finding was a mass lesion. Pathological diagnosis was made by image-guided biopsy in 44 % of patients. The imaging features of granulomatous mastitis on mammography are infrequently described. CONCLUSIONS: Our study demonstrates that granulomatous mastitis can occur in postmenopausal or asymptomatic patients, although previously reported exclusively in young women with palpable findings. Presentation on mammography as calcifications requiring mammographically guided vacuum-assisted biopsy has not been previously described. The diagnosis of granulomatous mastitis can easily be made by image-guided biopsy and surgical excision should be reserved for definitive treatment. KEY POINTS: • Characterizes radiographic appearance of granulomatous mastitis in postmenopausal or asymptomatic patients. • Granulomatous mastitis can present exclusively as calcifications on mammography. • The diagnosis of granulomatous mastitis is made by image-guided biopsy techniques. More... »

PAGES

2404-2411

References to SciGraph publications

  • 1926-03. Über Myome in VIRCHOWS ARCHIV A PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
  • 2010-03. Idiopathic Granulomatous Mastitis: Case Reports and Review of Literature in JOURNAL OF GENERAL INTERNAL MEDICINE
  • 2010-09. Erythema nodosum associated with granulomatous mastitis: report of two cases in RHEUMATOLOGY INTERNATIONAL
  • 2012-06. Multimodality imaging features of idiopathic granulomatous mastitis: outcome of 12 years of experience in LA RADIOLOGIA MEDICA
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00330-014-3273-z

    DOI

    http://dx.doi.org/10.1007/s00330-014-3273-z

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1021330729

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/24962828


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