C-arm CT during hepatic arteriography tumour-to-liver contrast: intraindividual comparison of three different contrast media application protocols View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-11-09

AUTHORS

Claus Koelblinger, Wolfgang Schima, Vanessa Berger-Kulemann, Florian Wolf, Christina Plank, Michael Weber, Johannes Lammer

ABSTRACT

ObjectiveTo compare tumour-to-liver contrast (TLC) of C-arm CT during hepatic arteriography (CACTHA) acquired using three protocols in patients with HCC.MethodsThis prospective study was IRB approved and informed consent was obtained from each patient. Twenty-nine patients (mean age, 68 ± 7 years; 27 men) with 55 HCCs (mean diameter, 2.6 ± 1.5 cm) underwent three different CACTHA protocols in random order before chemoembolisation. Contrast medium (100 mg iodine/ml) was injected into the common hepatic artery (flow rate 4 ml/s). The imaging delay for the start of the CACTHA examination was 4 s (protocol A), 8 s (protocol B) and 12 s (protocol C) (total amount of injected contrast medium: 48 ml, 64 ml, 80 ml). TLC was measured by placing regions of interest (ROIs) in the HCC and liver parenchyma. Mixed model ANOVAs and Bonferroni corrected post hoc tests were used for statistical analysis.ResultsMean values for TLC were 132 ± 3.3 HU, 186 ± 5.8 HU and 168 ± 2.8 HU for protocols A, B and C. Protocol B provided significantly higher TLC than protocols A and C (p < 0.001).ConclusionTLC was significantly higher using an imaging delay of 8 s compared with a delay of 4 or 12 s.Key Points• C-arm cone-beam CT (CACT) angiography offers additional information during hepatic intervention.• CACT hepatic arteriography tumour-to-liver contrast is highest with an 8-s delay.• An 8-s delay is recommended for early arterial phase CACTHA for hepatocelullar carcinoma. More... »

PAGES

938-942

References to SciGraph publications

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  • 2011-11-26. Diagnostic accuracy of C-arm CT during selective transcatheter angiography for hepatocellular carcinoma: comparison with intravenous contrast-enhanced, biphasic, dynamic MDCT in EUROPEAN RADIOLOGY
  • 2008-03-29. Detection of hepatocellular carcinoma by CT during arterial portography using a cone-beam CT technology: comparison with conventional CTAP in ABDOMINAL RADIOLOGY
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    http://scigraph.springernature.com/pub.10.1007/s00330-012-2697-6

    DOI

    http://dx.doi.org/10.1007/s00330-012-2697-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1015447353

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23138384


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