Ontology type: schema:ScholarlyArticle
2013-03
AUTHORSJi Yung Choo, Chang Min Park, Nyoung Keun Lee, Sang Min Lee, Hyun-Ju Lee, Jin Mo Goo
ABSTRACTOBJECTIVES: To describe our initial experience with percutaneous transthoracic needle biopsy (PCNB) of small (≤1 cm) lung nodules using a cone-beam computed tomography (CBCT) virtual navigation guidance system in 105 consecutive patients. METHODS: One hundred and five consecutive patients (55 male, 50 female; mean age, 62 years) with 107 small (≤1 cm) lung nodules (mean size, 0.85 cm ± 0.14) underwent PCNBs under CBCT virtual-navigation guidance system and constituted our study population. Procedural details-including radiation dose, sensitivity, specificity, diagnostic accuracy and complication rates of CBCT virtual navigation guided PCNBs-were described. RESULTS: The mean number of pleural passages with the coaxial needle, biopsies, CT acquisitions, total procedure time, coaxial introducer dwelling time, and estimated radiation exposure during PCNBs were 1.03 ± 0.21, 3.1 ± 0.7, 3.4 ± 1.3, 10.5 min ± 3.2 and 7.2 min ± 2.5, and 5.72 mSv ± 4.19, respectively. Sixty nodules (56.1 %) were diagnosed as malignant, 38 (35.5 %) as benign and nine (8.4 %) as indeterminate. The sensitivity, specificity, and diagnostic accuracy of CBCT virtual-navigation-guided PCNB for small (≤1 cm) nodules were 96.7 % (58/60), 100 % (38/38) and 98.0 % (96/98), respectively. Complications occurred in 13 (12.1 %) cases; pneumothorax in seven (6.5 %) and haemoptysis in six (5.6 %). CONCLUSION: CBCT virtual-navigation-guided PCNB is a highly accurate and safe diagnostic method for small (≤1 cm) nodules. More... »
PAGES712-719
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DOIhttp://dx.doi.org/10.1007/s00330-012-2644-6
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"description": "OBJECTIVES: To describe our initial experience with percutaneous transthoracic needle biopsy (PCNB) of small (\u22641 cm) lung nodules using a cone-beam computed tomography (CBCT) virtual navigation guidance system in 105 consecutive patients.\nMETHODS: One hundred and five consecutive patients (55 male, 50 female; mean age, 62 years) with 107 small (\u22641 cm) lung nodules (mean size, 0.85 cm\u2009\u00b1\u20090.14) underwent PCNBs under CBCT virtual-navigation guidance system and constituted our study population. Procedural details-including radiation dose, sensitivity, specificity, diagnostic accuracy and complication rates of CBCT virtual navigation guided PCNBs-were described.\nRESULTS: The mean number of pleural passages with the coaxial needle, biopsies, CT acquisitions, total procedure time, coaxial introducer dwelling time, and estimated radiation exposure during PCNBs were 1.03\u2009\u00b1\u20090.21, 3.1\u2009\u00b1\u20090.7, 3.4\u2009\u00b1\u20091.3, 10.5 min\u2009\u00b1\u20093.2 and 7.2 min\u2009\u00b1\u20092.5, and 5.72 mSv\u2009\u00b1\u20094.19, respectively. Sixty nodules (56.1 %) were diagnosed as malignant, 38 (35.5 %) as benign and nine (8.4 %) as indeterminate. The sensitivity, specificity, and diagnostic accuracy of CBCT virtual-navigation-guided PCNB for small (\u22641 cm) nodules were 96.7 % (58/60), 100 % (38/38) and 98.0 % (96/98), respectively. Complications occurred in 13 (12.1 %) cases; pneumothorax in seven (6.5 %) and haemoptysis in six (5.6 %).\nCONCLUSION: CBCT virtual-navigation-guided PCNB is a highly accurate and safe diagnostic method for small (\u22641 cm) nodules.",
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