Lung nodule volumetry: segmentation algorithms within the same software package cannot be used interchangeably View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-03-20

AUTHORS

H. Ashraf, B. de Hoop, S. B. Shaker, A. Dirksen, K. S. Bach, H. Hansen, M. Prokop, J. H. Pedersen

ABSTRACT

ObjectiveWe examined the reproducibility of lung nodule volumetry software that offers three different volumetry algorithms.MethodsIn a lung cancer screening trial, 188 baseline nodules >5 mm were identified. Including follow-ups, these nodules formed a study-set of 545 nodules. Nodules were independently double read by two readers using commercially available volumetry software. The software offers readers three different analysing algorithms. We compared the inter-observer variability of nodule volumetry when the readers used the same and different algorithms.ResultsBoth readers were able to correctly segment and measure 72% of nodules. In 80% of these cases, the readers chose the same algorithm. When readers used the same algorithm, exactly the same volume was measured in 50% of readings and a difference of >25% was observed in 4%. When the readers used different algorithms, 83% of measurements showed a difference of >25%.ConclusionModern volumetric software failed to correctly segment a high number of screen detected nodules. While choosing a different algorithm can yield better segmentation of a lung nodule, reproducibility of volumetric measurements deteriorates substantially when different algorithms were used. It is crucial even in the same software package to choose identical parameters for follow-up. More... »

PAGES

1878-1885

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00330-010-1749-z

DOI

http://dx.doi.org/10.1007/s00330-010-1749-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023054808

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20306082


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