The use of iodinated and gadolinium contrast media during pregnancy and lactation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-06

AUTHORS

Judith A. W. Webb, Henrik S. Thomsen, Sameh K. Morcos, Members of Contrast Media Safety Committee of European Society of Urogenital Radiology (ESUR)

ABSTRACT

The use of iodinated or gadolinium-based contrast media in pregnant or lactating women often causes concerns in the radiology department because of the principle of not exposing a fetus or neonate to any drugs. Because of the uncertainty about the use of contrast media during pregnancy and lactation, the Contrast Media Safety Committee of the European Society of Urogenital Radiology decided to review the literature and draw up guidelines. An extensive literature search was carried out and summarized in a report. Based on the limited information available, simple guidelines have been drawn up. The report and guidelines were discussed at the 11th European Symposium on Urogenital Radiology in Santiago de Compostela, Spain. Mutagenic and teratogenic effects have not been described after administration of gadolinium or iodinated contrast media. Free iodide in radiographic contrast medium given to the mother has the potential to depress fetal/neonatal thyroid function. Neonatal thyroid function should be checked during the 1st week if iodinated contrast media have been given during pregnancy. No effect on the fetus has been seen after gadolinium contrast media. Only tiny amounts of iodinated or gadolinium-based contrast medium given to a lactating mother reach the milk, and only a minute proportion entering the baby's gut is absorbed. The very small potential risk associated with absorption of contrast medium may be considered insufficient to warrant stopping breast-feeding for 24 h following either iodinated or gadolinium contrast agents. More... »

PAGES

1234-1240

References to SciGraph publications

  • 1980-10. Transient congenital hypothyroidism after amniofetography in EUROPEAN JOURNAL OF PEDIATRICS
  • 1980-01. Drug Excretion in Human Breast Milk in CLINICAL PHARMACOKINETICS
  • 1994. Fetal Physiology in MARSHALL’S PHYSIOLOGY OF REPRODUCTION
  • 2004-05. Effect of iodinated contrast media on thyroid function in adults in EUROPEAN RADIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00330-004-2583-y

    DOI

    http://dx.doi.org/10.1007/s00330-004-2583-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1000272147

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/15609057


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