Hyposalivation in autoimmune diseases View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Etsuko Maeshima, Kanako Furukawa, Shinichiro Maeshima, Hiroya Koshiba, Wataru Sakamoto

ABSTRACT

We have investigated the prevalence of dry mouth among patients with autoimmune diseases other than Sjögren's syndrome. One hundred and forty-four patients, excluding patients with primary Sjögren's syndrome, were enrolled in this study. The volume of saliva secreted was measured with the screening technique for estimation of salivary flow, which uses a filter paper for diagnosing dry mouth. Disturbed salivary secretion was observed in 84 (58.3 %) of the 144 patients. In the case of patients free of Sjögren's syndrome, the prevalence of disturbed salivary secretion differed significantly among the disease groups (P < 0.05), with the prevalence being over 50 % in all disease groups other than the rheumatoid arthritis group and the highest in the systemic sclerosis group. There was significant positive correlation between the number of colored spots and oral visual analog scale score (r = 0.45, P < 0.0001). Autoimmune diseases can be accompanied by salivary gland dysfunction, regardless of the presence/absence of complication by Sjögren's syndrome. In the present study, the screening technique for estimation of salivary flow, which uses a filter paper for diagnosing dry mouth, was shown to be a useful means of detecting salivary gland dysfunction. More... »

PAGES

3079-3082

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00296-012-2611-1

DOI

http://dx.doi.org/10.1007/s00296-012-2611-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011673029

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23274440


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