An age-structured model of epidermis growth View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-02-23

AUTHORS

Alberto Gandolfi, Mimmo Iannelli, Gabriela Marinoschi

ABSTRACT

We propose a model with age and space structure for the evolution of the supra-basal epidermis. The model includes different types of cells: proliferating cells, differentiated cells, corneous cells, and apoptotic cells. We assume that all cells move with the same velocity and that the local volume fraction, occupied by the cells is constant in space and time. This hypothesis, based on experimental evidence, allows us to determine a constitutive equation for the cell velocity. We focus on the stationary case of the problem, that takes the form of a quasi-linear evolution problem of first order, and we investigate conditions under which there is a solution. More... »

PAGES

111-141

References to SciGraph publications

  • 2007-02-21. Pathogenesis and therapy of psoriasis in NATURE
  • 2002-11. The steady state of a tumor cord cell population in JOURNAL OF EVOLUTION EQUATIONS
  • 1987-12. Epidermal cell proliferation in VIRCHOWS ARCHIV B CELL PATHOLOGY
  • 1987-12. Epidermal cell proliferation in VIRCHOWS ARCHIV B CELL PATHOLOGY
  • 2002-03. Getting under the skin of epidermal morphogenesis in NATURE REVIEWS GENETICS
  • 2008. Population Models Structured by Age, Size, and Spatial Position in STRUCTURED POPULATION MODELS IN BIOLOGY AND EPIDEMIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00285-010-0330-3

    DOI

    http://dx.doi.org/10.1007/s00285-010-0330-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1005239728

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20177685


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