Inhibitory Effects of Sulfur Nanoparticles on Membrane Lipids of Aspergillus niger: A Novel Route of Fungistasis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-07

AUTHORS

Samrat Roy Choudhury, Mahua Ghosh, Arunava Goswami

ABSTRACT

Orthorhombic (spherical; ~10 nm) and monoclinic (cylindrical; ~50 nm) sulfur nanoparticles (SNPs) were synthesized and examined for their effects on the total lipid content and desaturase enzymes of Aspergillus niger. Synthesized SNPs were characterized for size with transmission electron microscopy, elemental composition with energy dispersive X-ray spectroscopy and allotropic nature with X-ray diffraction pattern. Both the SNPs considerably reduced total lipid content of the treated fungal isolates with significant down regulation of the expression of various desaturase enzymes (linoleoyl-CoA desaturase, stearoyl-CoA 9-desaturase and phosphatidylcholine desaturase). Unusual high accumulation of saturated fatty acids with depleted lipid layer can be inferred as one of the major reasons of SNPs mediated fungistasis. More... »

PAGES

91-97

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00284-012-0130-7

DOI

http://dx.doi.org/10.1007/s00284-012-0130-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011352452

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22538469


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