Angiogenesis as a new target for cancer treatment View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-08

AUTHORS

M. Ono, Hiroto Izumi, Shigeo Yoshida, Daisuke Goto, Sei-ichiro Jimi, Naoyuki Kawahara, Tadahisa Shono, Shin Ushiro, Masahiro Ryuto, Kimitoshi Kohno, Yasafumi Sato, Michihiko Kuwano

ABSTRACT

Neovascularization is often required for rapid growth of solid tumors and also limits vascular metastasis of tumor cells. Neovascularization-targeting agents are a recent innovation that may be a novel means of anticancer therapy. These antiangiogenic drugs have been developed by targeting cell proliferation of vascular endothelial cells, basement-membrane-degrading enzymes, angiogenic factors/receptors, extracellular matrix, angiogenesis signaling, and cell-cell/cell-matrix interactions. In this report, we describe how tumor angiogenesis occurs and how antiangiogenic agents are developed. More... »

PAGES

s78-s82

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s002800051044

DOI

http://dx.doi.org/10.1007/s002800051044

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016931351

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8765423


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