Ontology type: schema:ScholarlyArticle
2013-08-15
AUTHORSThomas S. Y. Chan, Harinder Gill, Yu-Yan Hwang, Joycelyn Sim, Alan C. T. Tse, Florence Loong, Pek-Lan Khong, Eric Tse, Anskar Y. H. Leung, Chor-Sang Chim, Albert K. W. Lie, Yok-Lam Kwong
ABSTRACTThe frequency of breakthrough invasive fungal diseases (IFDs) during echinocandin therapy is unclear. We retrospectively analyzed 534 hematologic patients treated with echinocandin (caspofungin, N = 55; micafungin, N = 306; anidulafungin, N = 173). Four proven IFDs were found, caused by Candida parapsilosis (N = 2), C. parapsilosis and Candida glabrata (N = 1), and Fusarium species (N = 1). Four cases of possible IFDs were observed, all showing pulmonary infection. One case showed features suggestive of hepatosplenic candidiasis. Six of these eight cases had previously received the purine analog clofarabine. Breakthrough IFD during echinocandin treatment occurred infrequently (1.5 %), caused predominantly by Candida species. Clofarabine usage was an important risk factor. More... »
PAGES493-498
http://scigraph.springernature.com/pub.10.1007/s00277-013-1882-2
DOIhttp://dx.doi.org/10.1007/s00277-013-1882-2
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1042675123
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/23949318
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Public Health and Health Services",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adenine Nucleotides",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Anidulafungin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antibiotic Prophylaxis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antifungal Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antimetabolites, Antineoplastic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Arabinonucleosides",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Candida",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Candidiasis, Invasive",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Caspofungin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "China",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Clofarabine",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cohort Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cross Infection",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Echinocandins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Fusariosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Fusarium",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hematologic Diseases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hematopoietic Stem Cell Transplantation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunocompromised Host",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lipopeptides",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lung Diseases, Fungal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Micafungin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Retrospective Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Risk Factors",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Chan",
"givenName": "Thomas S. Y.",
"id": "sg:person.013304036752.03",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013304036752.03"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Gill",
"givenName": "Harinder",
"id": "sg:person.01171470630.09",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171470630.09"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Hwang",
"givenName": "Yu-Yan",
"id": "sg:person.01123355430.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123355430.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Sim",
"givenName": "Joycelyn",
"id": "sg:person.011416733702.66",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011416733702.66"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Tse",
"givenName": "Alan C. T.",
"id": "sg:person.0576130403.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576130403.05"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Pathology, Queen Mary Hospital, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Pathology, Queen Mary Hospital, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Loong",
"givenName": "Florence",
"id": "sg:person.0676541530.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0676541530.05"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Diagnostic Radiology, Queen Mary Hospital, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Diagnostic Radiology, Queen Mary Hospital, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Khong",
"givenName": "Pek-Lan",
"id": "sg:person.01040056637.02",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040056637.02"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Tse",
"givenName": "Eric",
"id": "sg:person.01126550300.26",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126550300.26"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Leung",
"givenName": "Anskar Y. H.",
"id": "sg:person.011121156664.42",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011121156664.42"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Chim",
"givenName": "Chor-Sang",
"id": "sg:person.0722115232.29",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722115232.29"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Lie",
"givenName": "Albert K. W.",
"id": "sg:person.010762116764.18",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010762116764.18"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China",
"id": "http://www.grid.ac/institutes/grid.415550.0",
"name": [
"Department of Medicine, Queen Mary Hospital, Professorial Block, Pokfulam Road, Hong Kong, China"
],
"type": "Organization"
},
"familyName": "Kwong",
"givenName": "Yok-Lam",
"id": "sg:person.01100514066.14",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100514066.14"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.2165/11585270-000000000-00000",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049836616",
"https://doi.org/10.2165/11585270-000000000-00000"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00277-011-1223-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025106768",
"https://doi.org/10.1007/s00277-011-1223-2"
],
"type": "CreativeWork"
}
],
"datePublished": "2013-08-15",
"datePublishedReg": "2013-08-15",
"description": "The frequency of breakthrough invasive fungal diseases (IFDs) during echinocandin therapy is unclear. We retrospectively analyzed 534 hematologic patients treated with echinocandin (caspofungin, N\u2009=\u200955; micafungin, N\u2009=\u2009306; anidulafungin, N\u2009=\u2009173). Four proven IFDs were found, caused by Candida parapsilosis (N\u2009=\u20092), C. parapsilosis and Candida glabrata (N\u2009=\u20091), and Fusarium species (N\u2009=\u20091). Four cases of possible IFDs were observed, all showing pulmonary infection. One case showed features suggestive of hepatosplenic candidiasis. Six of these eight cases had previously received the purine analog clofarabine. Breakthrough IFD during echinocandin treatment occurred infrequently (1.5\u00a0%), caused predominantly by Candida species. Clofarabine usage was an important risk factor.",
"genre": "article",
"id": "sg:pub.10.1007/s00277-013-1882-2",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1358129",
"issn": [
"0939-5555",
"1432-0584"
],
"name": "Annals of Hematology",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "3",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "93"
}
],
"keywords": [
"breakthrough invasive fungal disease",
"invasive fungal disease",
"hematologic patients",
"possible invasive fungal disease",
"echinocandin treatment",
"important risk factor",
"Proven Invasive Fungal Diseases",
"pulmonary infection",
"hepatosplenic candidiasis",
"risk factors",
"echinocandin therapy",
"Candida species",
"C. parapsilosis",
"patients",
"fungal diseases",
"Candida parapsilosis",
"Candida glabrata",
"disease",
"treatment",
"parapsilosis",
"therapy",
"candidiasis",
"clofarabine",
"infection",
"echinocandins",
"cases",
"glabrata",
"factors",
"Fusarium species",
"frequency",
"features",
"usage",
"species"
],
"name": "Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients",
"pagination": "493-498",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1042675123"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00277-013-1882-2"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"23949318"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00277-013-1882-2",
"https://app.dimensions.ai/details/publication/pub.1042675123"
],
"sdDataset": "articles",
"sdDatePublished": "2022-08-04T17:01",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_615.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s00277-013-1882-2"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00277-013-1882-2'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00277-013-1882-2'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00277-013-1882-2'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00277-013-1882-2'
This table displays all metadata directly associated to this object as RDF triples.
287 TRIPLES
21 PREDICATES
86 URIs
76 LITERALS
33 BLANK NODES