Ontology type: schema:ScholarlyArticle Open Access: True
2012-05
AUTHORSMoo-Kon Song, Joo-Seop Chung, Ho-Jin Shin, Sang-Min Lee, Su-Ee Lee, Ho-Sup Lee, Gyeong-Won Lee, Seong-Jang Kim, Seok-Mo Lee, Dong-Seop Chung
ABSTRACTThe objective of this study was to investigate whether metabolic tumor volume (MTV) by positron emission tomography (PET) can be a potential prognostic tool when compared with Ann Arbor stage, in stages II and III nodal diffuse large B cell lymphoma (DLBCL). We evaluated 169 patients with nodal stages II and III DLBCL who underwent measurements with PET prior to rituximab combined with cyclophosphamide, adriamycin, vincristine, and prednisone (R-CHOP). Cutoff point of MTV was measured using the receiver operating characteristic (ROC) curve. During a median period of 36 months, stage II was 59.2% and III was 40.8%. Using the ROC curve, the MTV of 220 cm(3) was the cutoff value. The low MTV group (<220 cm(3)) had longer progression-free survival (PFS) and overall survival (OS), compared with the high MTV group (≥220 cm(3)) (p < 0.001, p < 0.001). Stage II patients had longer survival than those in stage III (PFS, p = 0.011; OS, p = 0.001). The high MTV group had lower PFS and OS patterns, regardless of stage, compared with the low MTV group (p < 0.001, p < 0.001). Multivariate analysis revealed an association of the high MTV group with lower PFS and OS (PFS, hazard ratio (HR) = 5.300, p < 0.001; OS, HR = 7.009, p < 0.001), but not stage III (PFS, p = 0.187; OS, p = 0.054). Assessment of MTV by PET had more potential predictive power than Ann Arbor stage in the patients that received R-CHOP. More... »
PAGES697-703
http://scigraph.springernature.com/pub.10.1007/s00277-011-1357-2
DOIhttp://dx.doi.org/10.1007/s00277-011-1357-2
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1044492024
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/22071570
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antineoplastic Combined Chemotherapy Protocols",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Fluorodeoxyglucose F18",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lymphoma, Large B-Cell, Diffuse",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Multimodal Imaging",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neoplasm Staging",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Positron-Emission Tomography",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prognosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Reference Values",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tomography, X-Ray Computed",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Treatment Outcome",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tumor Burden",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Young Adult",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"name": [
"Department of Hematology\u2013Oncology, Busan Cancer Center, Pusan National University Hospital Medical Research Institute, 1-10 Ami-dong, Seo-gu, 602-739, Busan, Republic of Korea"
],
"type": "Organization"
},
"familyName": "Song",
"givenName": "Moo-Kon",
"id": "sg:person.0667362003.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667362003.41"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Hematology\u2013Oncology, Busan Cancer Center, Pusan National University Hospital Medical Research Institute, 1-10 Ami-dong, Seo-gu, 602-739, Busan, Republic of Korea"
],
"type": "Organization"
},
"familyName": "Chung",
"givenName": "Joo-Seop",
"id": "sg:person.0643051642.83",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643051642.83"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Hematology\u2013Oncology, Busan Cancer Center, Pusan National University Hospital Medical Research Institute, 1-10 Ami-dong, Seo-gu, 602-739, Busan, Republic of Korea"
],
"type": "Organization"
},
"familyName": "Shin",
"givenName": "Ho-Jin",
"id": "sg:person.01046763234.19",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046763234.19"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Inje University Busan Paik Hospital",
"id": "https://www.grid.ac/institutes/grid.411625.5",
"name": [
"Department of Hematology\u2013Oncology, Busan Paik Hospital, Busan, South Korea"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Sang-Min",
"id": "sg:person.01315300754.59",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315300754.59"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Dong-A University Hospital",
"id": "https://www.grid.ac/institutes/grid.412048.b",
"name": [
"Department of Hematology, Dong-A University Medical Center, Busan, South Korea"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Su-Ee",
"id": "sg:person.01046051525.92",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046051525.92"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Kosin University Gospel Hospital",
"id": "https://www.grid.ac/institutes/grid.411145.4",
"name": [
"Department of hematology, Kosin University Gospel Hospital, Busan, South Korea"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Ho-Sup",
"id": "sg:person.0670171614.80",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670171614.80"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Gyeongsang National University Hospital",
"id": "https://www.grid.ac/institutes/grid.411899.c",
"name": [
"Department of hematology, Gyeongsang National University Hospital, Jinju, South Korea"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Gyeong-Won",
"id": "sg:person.01051706014.23",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051706014.23"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Pusan National University Hospital",
"id": "https://www.grid.ac/institutes/grid.412588.2",
"name": [
"Department of Nuclear Medicine, Pusan National University Hospital, Busan, South Korea"
],
"type": "Organization"
},
"familyName": "Kim",
"givenName": "Seong-Jang",
"id": "sg:person.0631446453.19",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631446453.19"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Inje University Busan Paik Hospital",
"id": "https://www.grid.ac/institutes/grid.411625.5",
"name": [
"Department of Nuclear Medicine, Busan Paik Hospital, Busan, South Korea"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Seok-Mo",
"id": "sg:person.01164751666.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01164751666.52"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Industry\u2013University Cooperation Foundation, Kyung Sung University, Busan, South Korea"
],
"type": "Organization"
},
"familyName": "Chung",
"givenName": "Dong-Seop",
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1016/s1470-2045(06)70664-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001953896"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2009.26.2493",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005877831"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1182/blood-2005-01-0272",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005883285"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejm199309303291402",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013554742"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/1097-0142(197610)38:4<1484::aid-cncr2820380407>3.0.co;2-i",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023272157"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2005.09.131",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025938087"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11307-010-0404-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028833037",
"https://doi.org/10.1007/s11307-010-0404-z"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1182/blood-2003-06-2094",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035740893"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/rlu.0b013e3181d18eb0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039854667"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/rlu.0b013e3181d18eb0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039854667"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00259-003-1375-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040833284",
"https://doi.org/10.1007/s00259-003-1375-y"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/nbm.1689",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042588862"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2005.05.1003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043142474"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejm199304083281404",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043239598"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/annonc/mdf256",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044003802"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2006.09.2403",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045509899"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1470-2045(08)70002-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047262140"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.ijrobp.2008.10.060",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048297290"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.ijrobp.2008.10.060",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048297290"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa011795",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052302729"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2005.02.4786",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064204195"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2005.05.012",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064204242"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.1986.4.6.859",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1078813741"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.1989.7.11.1630",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1079394416"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080822412",
"type": "CreativeWork"
}
],
"datePublished": "2012-05",
"datePublishedReg": "2012-05-01",
"description": "The objective of this study was to investigate whether metabolic tumor volume (MTV) by positron emission tomography (PET) can be a potential prognostic tool when compared with Ann Arbor stage, in stages II and III nodal diffuse large B cell lymphoma (DLBCL). We evaluated 169 patients with nodal stages II and III DLBCL who underwent measurements with PET prior to rituximab combined with cyclophosphamide, adriamycin, vincristine, and prednisone (R-CHOP). Cutoff point of MTV was measured using the receiver operating characteristic (ROC) curve. During a median period of 36\u00a0months, stage II was 59.2% and III was 40.8%. Using the ROC curve, the MTV of 220\u00a0cm(3) was the cutoff value. The low MTV group (<220\u00a0cm(3)) had longer progression-free survival (PFS) and overall survival (OS), compared with the high MTV group (\u2265220\u00a0cm(3)) (p\u2009<\u20090.001, p\u2009<\u20090.001). Stage II patients had longer survival than those in stage III (PFS, p\u2009=\u20090.011; OS, p\u2009=\u20090.001). The high MTV group had lower PFS and OS patterns, regardless of stage, compared with the low MTV group (p\u2009<\u20090.001, p\u2009<\u20090.001). Multivariate analysis revealed an association of the high MTV group with lower PFS and OS (PFS, hazard ratio (HR)\u2009=\u20095.300, p\u2009<\u20090.001; OS, HR\u2009=\u20097.009, p\u2009<\u20090.001), but not stage III (PFS, p\u2009=\u20090.187; OS, p\u2009=\u20090.054). Assessment of MTV by PET had more potential predictive power than Ann Arbor stage in the patients that received R-CHOP.",
"genre": "research_article",
"id": "sg:pub.10.1007/s00277-011-1357-2",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1018247",
"issn": [
"1269-3286",
"1279-8509"
],
"name": "Annals of Hematology",
"type": "Periodical"
},
{
"issueNumber": "5",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "91"
}
],
"name": "Clinical significance of metabolic tumor volume by PET/CT in stages II and III of diffuse large B cell lymphoma without extranodal site involvement",
"pagination": "697-703",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"d3eea94f7aa5f6e58263d89b4087cc1add275a558150385c864f9d395b78263f"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"22071570"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9107334"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00277-011-1357-2"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1044492024"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00277-011-1357-2",
"https://app.dimensions.ai/details/publication/pub.1044492024"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T16:37",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000491.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/s00277-011-1357-2"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00277-011-1357-2'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00277-011-1357-2'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00277-011-1357-2'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00277-011-1357-2'
This table displays all metadata directly associated to this object as RDF triples.
294 TRIPLES
21 PREDICATES
70 URIs
39 LITERALS
27 BLANK NODES