Safety of CT-Guided Microwave Ablation of Subcardiac Liver Tumors View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2022-08-08

AUTHORS

William Johnson, Adam Weekley, Pilar Suz, Nainesh Parikh, Ghassan El-Haddad, Rahul Mhaskar, Bela Kis

ABSTRACT

PurposeThe purpose of this study was to investigate the safety of CT-guided microwave ablation (MWA) of subcardiac hepatic tumors.Materials and MethodsThis retrospective study included 19 patients (11 males and 8 females, age: 64.0 years (IQR: 58.3, 71.0) who underwent CT-guided MWA of 22 subcardiac tumors from January 2016 through December 2020. The subcardiac tumors consisted of 6 hepatocellular carcinomas and 16 metastases. Hydrodissection or other thermal protection technique was not used during the ablation. Subcardiac ablation was defined as the ablation zone extended ≤ 0.5 cm from myocardium or coronary artery. The safety of MWA of subcardiac tumors was evaluated based on procedural and post-procedural complications and intra-procedural ECG changes. Local tumor progression (LTP) was also analyzed and correlated with tumor and ablation zone sizes.ResultsThe primary efficacy rate was 100%. The median follow-up was 20.5 months (IQR: 6.0, 29.8). There was no 30-day mortality. One grade 3 complication occurred (severe shoulder and chest pain), and there were 19 events of grade 1 or 2 complications. No instances of cardiac complications or significant procedural ECG changes were observed. There were 22 events of grade 1 and 2 laboratory toxicity and 1 event of grade 3 elevated bilirubin. The LTP was 13.6% at 1 year and 22.7% at 2 years. There was no significant correlation between LTP and tumor or ablation zone sizes.ConclusionCT-guided MWA of subcardiac hepatic tumors is safe, and MWA should be considered as an option for managing subcardiac tumors. LTP rates for MWA of subcardiac tumors may be inferior to ablation of tumors in common location.Level of Evidence IIICohort Study. More... »

PAGES

1693-1700

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URI

http://scigraph.springernature.com/pub.10.1007/s00270-022-03235-7

DOI

http://dx.doi.org/10.1007/s00270-022-03235-7

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https://app.dimensions.ai/details/publication/pub.1150071336

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/35941243


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