Duodenal but not gastric transection disturbs motility of the sphincter of Oddi in the dog View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-02

AUTHORS

Chikashi Shibata, Iwao Sasaki, Hiroo Naito, Noriya Ohtani, Shoichi Sato, Hideo Ise, Seiki Matsuno

ABSTRACT

The aim of the present study was to elucidate the effect of gastric and duodenal transection on biliary manometry in anesthetized dogs. The basal biliary pressure and increase in pressure during saline perfusion at rates of 1.0 and 1.5 ml/min were studied in intact controls, during infusion of cholecystokinin (CCK) alone, and after gastric and duodenal transection. CCK dose-dependently lowered the basal pressure and the increase in pressure during perfusion. Gastric transection 1.5 cm proximal to the pylorus did not affect these parameters. In contrast, duodenal transection 1.0 cm distal to the pylorus significantly increased these parameters compared to all other groups. These observations suggest that the proximal duodenal transection, as performed during conventional distal gastrectomy, may contribute to the pathogenesis of postgastrectomy gallstone formation by altering motor function of the sphincter of Oddi. More... »

PAGES

191-194

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s002689900214

DOI

http://dx.doi.org/10.1007/s002689900214

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023274100

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8995077


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