A Novel Parameter Identified Using Indocyanine Green Fluorescence Angiography may Contribute to Predicting Anastomotic Leakage in Gastric Cancer Surgery View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2020-03-29

AUTHORS

Mikito Mori, Kiyohiko Shuto, Atsushi Hirano, Chihiro Kosugi, Kazuo Narushima, Isamu Hosokawa, Masafumi Fujino, Masato Yamazaki, Hiroaki Shimizu, Keiji Koda

ABSTRACT

BackgroundAnastomotic leak is one of the most serious postoperative complications, and intraoperative adequate perfusion plays a key role in preventing its development in gastric cancer surgery. This study aimed to investigate the relationships between anastomotic leak and the parameters defined by an assessment of intraoperative anastomotic perfusion using a near-infrared indocyanine green (ICG) fluorescence system and to evaluate the usefulness of this ICG fluorescence assessment in gastric cancer surgery.MethodsWe retrospectively reviewed data of 100 patients who underwent gastric cancer surgery. In a visual assessment based on fluorescence intensity, we classified ICG fluorescence image patterns as homogeneous, heterogeneous, or faint. In a chronological assessment, the first or second time point of ICG fluorescence appearance on one or the other side of the anastomosis was defined as FT or ST, respectively. The time difference in ICG fluorescence appearance between FT and ST was defined as TD. The relationships between anastomotic leak and the evaluated clinical factors, including the parameters identified by the ICG fluorescence assessment, were evaluated using univariate or multivariate analysis.ResultsAlthough no signs of leak were found by surgeons’ subjective judgments, four patients developed postoperative anastomotic leak of Clavien–Dindo grade III or IV. Multivariate analysis revealed that TD was an independent predictor of anastomotic leak (odds ratio 35.361, 95% confidence interval 1.489–839.923, p = 0.027).ConclusionsA novel parameter identified using near-infrared ICG fluorescence assessment may be useful to predict anastomotic leak in gastric cancer surgery.Trial RegistrationUMIN Clinical Trials Registry: #UMIN000030747 (https://www.umin.ac.jp/ctr/index.htm). More... »

PAGES

2699-2708

References to SciGraph publications

  • 2016-06-28. Evaluation of intestinal perfusion by ICG fluorescence imaging in laparoscopic colorectal surgery with DST anastomosis in SURGICAL ENDOSCOPY
  • 2016-08-23. Indocyanine green fluorescence angiography during laparoscopic low anterior resection: results of a case-matched study in SURGICAL ENDOSCOPY
  • 2011-09-10. Usefulness of blood supply visualization by indocyanine green fluorescence for reconstruction during esophagectomy in ESOPHAGUS
  • 2016-03-11. Indocyanine green fluorescence angiography for intraoperative assessment of gastrointestinal anastomotic perfusion: a systematic review of clinical trials in LANGENBECK'S ARCHIVES OF SURGERY
  • 2010-12-07. Comparison of Billroth I and Billroth II reconstructions after laparoscopy-assisted distal gastrectomy: a retrospective analysis of large-scale multicenter results from Korea in SURGICAL ENDOSCOPY
  • 2016-10-26. Stomach in AJCC CANCER STAGING MANUAL
  • 2006-11-03. Laser Doppler assessment of the influence of division at the root of the inferior mesenteric artery on anastomotic blood flow in rectosigmoid cancer surgery in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2015-07-21. Current Trends and Emerging Future of Indocyanine Green Usage in Surgery and Oncology: An Update in ANNALS OF SURGICAL ONCOLOGY
  • 2011-05-20. Reconstruction of the esophagojejunostomy by double stapling method using EEA™ OrVil™ in laparoscopic total gastrectomy and proximal gastrectomy in WORLD JOURNAL OF SURGICAL ONCOLOGY
  • 1994-11. Left-sided colon and colorectal anastomoses: doppler ultrasound as an aid to assess bowel vascularization in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2016-06-30. Morbidity and Mortality After Gastrectomy: Identification of Modifiable Risk Factors in JOURNAL OF GASTROINTESTINAL SURGERY
  • 2018-05-15. Prognostic Significance of Post-Operative Morbidity Severity Score After Potentially Curative D2 Gastrectomy for Carcinoma in JOURNAL OF GASTROINTESTINAL SURGERY
  • 2009-02-17. Surgeons lack predictive accuracy for anastomotic leakage in gastrointestinal surgery in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2017-06-28. Prevalence of anastomotic leak and the impact of indocyanine green fluorescein imaging for evaluating blood flow in the gastric conduit following esophageal cancer surgery in ESOPHAGUS
  • 2016-09-16. Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage in JOURNAL OF GASTROINTESTINAL SURGERY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00268-020-05488-0

    DOI

    http://dx.doi.org/10.1007/s00268-020-05488-0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1125975570

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/32227275


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged, 80 and over", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Anastomotic Leak", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Coloring Agents", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Fluorescein Angiography", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Indocyanine Green", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Retrospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Stomach Neoplasms", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare Ichikawa Hospital, 6-1-14 Kounodai, 272-0827, Ichikawa, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
                "Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare Ichikawa Hospital, 6-1-14 Kounodai, 272-0827, Ichikawa, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mori", 
            "givenName": "Mikito", 
            "id": "sg:person.01133656514.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133656514.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shuto", 
            "givenName": "Kiyohiko", 
            "id": "sg:person.01361326355.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361326355.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare Ichikawa Hospital, 6-1-14 Kounodai, 272-0827, Ichikawa, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
                "Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare Ichikawa Hospital, 6-1-14 Kounodai, 272-0827, Ichikawa, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hirano", 
            "givenName": "Atsushi", 
            "id": "sg:person.01257014672.12", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257014672.12"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kosugi", 
            "givenName": "Chihiro", 
            "id": "sg:person.01213167443.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213167443.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare Ichikawa Hospital, 6-1-14 Kounodai, 272-0827, Ichikawa, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
                "Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare Ichikawa Hospital, 6-1-14 Kounodai, 272-0827, Ichikawa, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Narushima", 
            "givenName": "Kazuo", 
            "id": "sg:person.01245236012.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245236012.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hosokawa", 
            "givenName": "Isamu", 
            "id": "sg:person.0700157264.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700157264.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fujino", 
            "givenName": "Masafumi", 
            "id": "sg:person.010335623561.62", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010335623561.62"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yamazaki", 
            "givenName": "Masato", 
            "id": "sg:person.0647637172.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647637172.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shimizu", 
            "givenName": "Hiroaki", 
            "id": "sg:person.01103413111.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103413111.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Koda", 
            "givenName": "Keiji", 
            "id": "sg:person.0647155176.80", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647155176.80"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s00464-016-5181-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027260581", 
              "https://doi.org/10.1007/s00464-016-5181-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00292253", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031031741", 
              "https://doi.org/10.1007/bf00292253"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10388-011-0291-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020889898", 
              "https://doi.org/10.1007/s10388-011-0291-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00464-016-5064-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014302636", 
              "https://doi.org/10.1007/s00464-016-5064-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1477-7819-9-55", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013805157", 
              "https://doi.org/10.1186/1477-7819-9-55"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11605-016-3255-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039755023", 
              "https://doi.org/10.1007/s11605-016-3255-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-3-319-40618-3_17", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1087262094", 
              "https://doi.org/10.1007/978-3-319-40618-3_17"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10388-017-0585-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090281791", 
              "https://doi.org/10.1007/s10388-017-0585-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00384-006-0221-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004968252", 
              "https://doi.org/10.1007/s00384-006-0221-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00384-009-0658-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018409767", 
              "https://doi.org/10.1007/s00384-009-0658-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00423-016-1400-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024297110", 
              "https://doi.org/10.1007/s00423-016-1400-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11605-018-3787-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1103995280", 
              "https://doi.org/10.1007/s11605-018-3787-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00464-010-1493-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033808049", 
              "https://doi.org/10.1007/s00464-010-1493-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1245/s10434-015-4743-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028715455", 
              "https://doi.org/10.1245/s10434-015-4743-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11605-016-3195-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001396468", 
              "https://doi.org/10.1007/s11605-016-3195-y"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2020-03-29", 
        "datePublishedReg": "2020-03-29", 
        "description": "BackgroundAnastomotic leak is one of the most serious postoperative complications, and intraoperative adequate perfusion plays a key role in preventing its development in gastric cancer surgery. This study aimed to investigate the relationships between anastomotic leak and the parameters defined by an assessment of intraoperative anastomotic perfusion using a near-infrared indocyanine green (ICG) fluorescence system and to evaluate the usefulness of this ICG fluorescence assessment in gastric cancer surgery.MethodsWe retrospectively reviewed data of 100 patients who underwent gastric cancer surgery. In a visual assessment based on fluorescence intensity, we classified ICG fluorescence image patterns as homogeneous, heterogeneous, or faint. In a chronological assessment, the first or second time point of ICG fluorescence appearance on one or the other side of the anastomosis was defined as FT or ST, respectively. The time difference in ICG fluorescence appearance between FT and ST was defined as TD. The relationships between anastomotic leak and the evaluated clinical factors, including the parameters identified by the ICG fluorescence assessment, were evaluated using univariate or multivariate analysis.ResultsAlthough no signs of leak were found by surgeons\u2019 subjective judgments, four patients developed postoperative anastomotic leak of Clavien\u2013Dindo grade III or IV. Multivariate analysis revealed that TD was an independent predictor of anastomotic leak (odds ratio 35.361, 95% confidence interval 1.489\u2013839.923, p\u2009=\u20090.027).ConclusionsA novel parameter identified using near-infrared ICG fluorescence assessment may be useful to predict anastomotic leak in gastric cancer surgery.Trial RegistrationUMIN Clinical Trials Registry: #UMIN000030747 (https://www.umin.ac.jp/ctr/index.htm).", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s00268-020-05488-0", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1086446", 
            "issn": [
              "0364-2313", 
              "1432-2323"
            ], 
            "name": "World Journal of Surgery", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "8", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "44"
          }
        ], 
        "keywords": [
          "gastric cancer surgery", 
          "anastomotic leak", 
          "cancer surgery", 
          "indocyanine green fluorescence system", 
          "Clavien-Dindo grade III", 
          "indocyanine green fluorescence angiography", 
          "evaluated clinical factors", 
          "postoperative anastomotic leak", 
          "Predicting Anastomotic Leakage", 
          "serious postoperative complications", 
          "surgeons' subjective judgment", 
          "fluorescence assessment", 
          "postoperative complications", 
          "clinical factors", 
          "independent predictors", 
          "anastomotic leakage", 
          "anastomotic perfusion", 
          "signs of leak", 
          "grade III", 
          "BackgroundAnastomotic leak", 
          "adequate perfusion", 
          "fluorescence angiography", 
          "surgery", 
          "second time point", 
          "multivariate analysis", 
          "novel parameter", 
          "time points", 
          "patients", 
          "perfusion", 
          "leak", 
          "visual assessment", 
          "assessment", 
          "complications", 
          "angiography", 
          "anastomosis", 
          "MethodsWe", 
          "ResultsAlthough", 
          "univariate", 
          "key role", 
          "predictors", 
          "signs", 
          "appearance", 
          "ST", 
          "factors", 
          "differences", 
          "fluorescence appearance", 
          "relationship", 
          "study", 
          "role", 
          "chronological assessment", 
          "usefulness", 
          "fluorescence intensity", 
          "analysis", 
          "time difference", 
          "leakage", 
          "patterns", 
          "fluorescence system", 
          "data", 
          "subjective judgment", 
          "development", 
          "TD", 
          "side", 
          "parameters", 
          "image patterns", 
          "intensity", 
          "point", 
          "ft", 
          "judgments", 
          "system"
        ], 
        "name": "A Novel Parameter Identified Using Indocyanine Green Fluorescence Angiography may Contribute to Predicting Anastomotic Leakage in Gastric Cancer Surgery", 
        "pagination": "2699-2708", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1125975570"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00268-020-05488-0"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "32227275"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00268-020-05488-0", 
          "https://app.dimensions.ai/details/publication/pub.1125975570"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-10-01T06:48", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_872.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s00268-020-05488-0"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00268-020-05488-0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00268-020-05488-0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00268-020-05488-0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00268-020-05488-0'


     

    This table displays all metadata directly associated to this object as RDF triples.

    309 TRIPLES      21 PREDICATES      122 URIs      99 LITERALS      20 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00268-020-05488-0 schema:about N0998b7dbb08443198e2e607a59ea3e82
    2 N0cc71a026cc04ca9b8746a87c08b0591
    3 N1987d2eea33244b6bdae2541d68da300
    4 N27a8f929ca504457ac6f80734eb486ba
    5 N430c502a7011416dab2ddced9e8d98b1
    6 N536577dd55f94b578c818f09c411a50c
    7 N6502a0b9060a49cf9f8990acbb9a5686
    8 N6fb30d64662a461290f6006f18750e77
    9 N84034b6befb14594a6585af5fffb53d2
    10 Nd3a9980780ef4730803c52faece94df7
    11 Nddad0183ec0043dbb12fddcb3102bab8
    12 Nf52669481214408599fc777b3cb3aba0
    13 Nff7d9f6e128843cbb6481024f15534d0
    14 anzsrc-for:11
    15 anzsrc-for:1112
    16 schema:author Nbf84d04814d84e82b8231c44a7bc2a66
    17 schema:citation sg:pub.10.1007/978-3-319-40618-3_17
    18 sg:pub.10.1007/bf00292253
    19 sg:pub.10.1007/s00384-006-0221-7
    20 sg:pub.10.1007/s00384-009-0658-6
    21 sg:pub.10.1007/s00423-016-1400-9
    22 sg:pub.10.1007/s00464-010-1493-0
    23 sg:pub.10.1007/s00464-016-5064-x
    24 sg:pub.10.1007/s00464-016-5181-6
    25 sg:pub.10.1007/s10388-011-0291-7
    26 sg:pub.10.1007/s10388-017-0585-5
    27 sg:pub.10.1007/s11605-016-3195-y
    28 sg:pub.10.1007/s11605-016-3255-3
    29 sg:pub.10.1007/s11605-018-3787-9
    30 sg:pub.10.1186/1477-7819-9-55
    31 sg:pub.10.1245/s10434-015-4743-5
    32 schema:datePublished 2020-03-29
    33 schema:datePublishedReg 2020-03-29
    34 schema:description BackgroundAnastomotic leak is one of the most serious postoperative complications, and intraoperative adequate perfusion plays a key role in preventing its development in gastric cancer surgery. This study aimed to investigate the relationships between anastomotic leak and the parameters defined by an assessment of intraoperative anastomotic perfusion using a near-infrared indocyanine green (ICG) fluorescence system and to evaluate the usefulness of this ICG fluorescence assessment in gastric cancer surgery.MethodsWe retrospectively reviewed data of 100 patients who underwent gastric cancer surgery. In a visual assessment based on fluorescence intensity, we classified ICG fluorescence image patterns as homogeneous, heterogeneous, or faint. In a chronological assessment, the first or second time point of ICG fluorescence appearance on one or the other side of the anastomosis was defined as FT or ST, respectively. The time difference in ICG fluorescence appearance between FT and ST was defined as TD. The relationships between anastomotic leak and the evaluated clinical factors, including the parameters identified by the ICG fluorescence assessment, were evaluated using univariate or multivariate analysis.ResultsAlthough no signs of leak were found by surgeons’ subjective judgments, four patients developed postoperative anastomotic leak of Clavien–Dindo grade III or IV. Multivariate analysis revealed that TD was an independent predictor of anastomotic leak (odds ratio 35.361, 95% confidence interval 1.489–839.923, p = 0.027).ConclusionsA novel parameter identified using near-infrared ICG fluorescence assessment may be useful to predict anastomotic leak in gastric cancer surgery.Trial RegistrationUMIN Clinical Trials Registry: #UMIN000030747 (https://www.umin.ac.jp/ctr/index.htm).
    35 schema:genre article
    36 schema:isAccessibleForFree false
    37 schema:isPartOf N57679776d2204eeea0c6ea575c02efce
    38 Nbeb1ed478363429faa9147abeaee5e06
    39 sg:journal.1086446
    40 schema:keywords BackgroundAnastomotic leak
    41 Clavien-Dindo grade III
    42 MethodsWe
    43 Predicting Anastomotic Leakage
    44 ResultsAlthough
    45 ST
    46 TD
    47 adequate perfusion
    48 analysis
    49 anastomosis
    50 anastomotic leak
    51 anastomotic leakage
    52 anastomotic perfusion
    53 angiography
    54 appearance
    55 assessment
    56 cancer surgery
    57 chronological assessment
    58 clinical factors
    59 complications
    60 data
    61 development
    62 differences
    63 evaluated clinical factors
    64 factors
    65 fluorescence angiography
    66 fluorescence appearance
    67 fluorescence assessment
    68 fluorescence intensity
    69 fluorescence system
    70 ft
    71 gastric cancer surgery
    72 grade III
    73 image patterns
    74 independent predictors
    75 indocyanine green fluorescence angiography
    76 indocyanine green fluorescence system
    77 intensity
    78 judgments
    79 key role
    80 leak
    81 leakage
    82 multivariate analysis
    83 novel parameter
    84 parameters
    85 patients
    86 patterns
    87 perfusion
    88 point
    89 postoperative anastomotic leak
    90 postoperative complications
    91 predictors
    92 relationship
    93 role
    94 second time point
    95 serious postoperative complications
    96 side
    97 signs
    98 signs of leak
    99 study
    100 subjective judgment
    101 surgeons' subjective judgment
    102 surgery
    103 system
    104 time difference
    105 time points
    106 univariate
    107 usefulness
    108 visual assessment
    109 schema:name A Novel Parameter Identified Using Indocyanine Green Fluorescence Angiography may Contribute to Predicting Anastomotic Leakage in Gastric Cancer Surgery
    110 schema:pagination 2699-2708
    111 schema:productId N07beffb509f24384aa8eb09f06717ce1
    112 N20cb595646c24548af222954da6a47e9
    113 N85450a0179bc434dafa707d581f19131
    114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1125975570
    115 https://doi.org/10.1007/s00268-020-05488-0
    116 schema:sdDatePublished 2022-10-01T06:48
    117 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    118 schema:sdPublisher N36638a16142a40b1bcd6a73cd229a043
    119 schema:url https://doi.org/10.1007/s00268-020-05488-0
    120 sgo:license sg:explorer/license/
    121 sgo:sdDataset articles
    122 rdf:type schema:ScholarlyArticle
    123 N07beffb509f24384aa8eb09f06717ce1 schema:name pubmed_id
    124 schema:value 32227275
    125 rdf:type schema:PropertyValue
    126 N0998b7dbb08443198e2e607a59ea3e82 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    127 schema:name Anastomotic Leak
    128 rdf:type schema:DefinedTerm
    129 N0cc71a026cc04ca9b8746a87c08b0591 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    130 schema:name Aged, 80 and over
    131 rdf:type schema:DefinedTerm
    132 N0ccc7989dec246008a5b0c72dc153a66 rdf:first sg:person.01245236012.98
    133 rdf:rest N23029d9eac334e82ac1859edad76c745
    134 N11a400c48e814ab99b8fe58e9f2c02c1 rdf:first sg:person.01257014672.12
    135 rdf:rest N9d9a828e2de64e1da7ad42cf0b0719b7
    136 N165eb215f7574617a2fd24c7103faef2 rdf:first sg:person.01361326355.05
    137 rdf:rest N11a400c48e814ab99b8fe58e9f2c02c1
    138 N1987d2eea33244b6bdae2541d68da300 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    139 schema:name Indocyanine Green
    140 rdf:type schema:DefinedTerm
    141 N20cb595646c24548af222954da6a47e9 schema:name doi
    142 schema:value 10.1007/s00268-020-05488-0
    143 rdf:type schema:PropertyValue
    144 N23029d9eac334e82ac1859edad76c745 rdf:first sg:person.0700157264.27
    145 rdf:rest N5c0a477057514a84a2ef42b3b76f6809
    146 N27a8f929ca504457ac6f80734eb486ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    147 schema:name Middle Aged
    148 rdf:type schema:DefinedTerm
    149 N36638a16142a40b1bcd6a73cd229a043 schema:name Springer Nature - SN SciGraph project
    150 rdf:type schema:Organization
    151 N430c502a7011416dab2ddced9e8d98b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Aged
    153 rdf:type schema:DefinedTerm
    154 N536577dd55f94b578c818f09c411a50c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    155 schema:name Retrospective Studies
    156 rdf:type schema:DefinedTerm
    157 N57679776d2204eeea0c6ea575c02efce schema:volumeNumber 44
    158 rdf:type schema:PublicationVolume
    159 N5c0a477057514a84a2ef42b3b76f6809 rdf:first sg:person.010335623561.62
    160 rdf:rest Na59217653407458fa8521b904d8e5dd4
    161 N643612916f39461692b3b8af870ba7dc rdf:first sg:person.0647155176.80
    162 rdf:rest rdf:nil
    163 N6502a0b9060a49cf9f8990acbb9a5686 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    164 schema:name Stomach Neoplasms
    165 rdf:type schema:DefinedTerm
    166 N6fb30d64662a461290f6006f18750e77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    167 schema:name Female
    168 rdf:type schema:DefinedTerm
    169 N84034b6befb14594a6585af5fffb53d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    170 schema:name Male
    171 rdf:type schema:DefinedTerm
    172 N85450a0179bc434dafa707d581f19131 schema:name dimensions_id
    173 schema:value pub.1125975570
    174 rdf:type schema:PropertyValue
    175 N9d9a828e2de64e1da7ad42cf0b0719b7 rdf:first sg:person.01213167443.37
    176 rdf:rest N0ccc7989dec246008a5b0c72dc153a66
    177 Na59217653407458fa8521b904d8e5dd4 rdf:first sg:person.0647637172.13
    178 rdf:rest Nb0bcd45953424551b017d5384cf6f75c
    179 Nb0bcd45953424551b017d5384cf6f75c rdf:first sg:person.01103413111.45
    180 rdf:rest N643612916f39461692b3b8af870ba7dc
    181 Nbeb1ed478363429faa9147abeaee5e06 schema:issueNumber 8
    182 rdf:type schema:PublicationIssue
    183 Nbf84d04814d84e82b8231c44a7bc2a66 rdf:first sg:person.01133656514.23
    184 rdf:rest N165eb215f7574617a2fd24c7103faef2
    185 Nd3a9980780ef4730803c52faece94df7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    186 schema:name Humans
    187 rdf:type schema:DefinedTerm
    188 Nddad0183ec0043dbb12fddcb3102bab8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    189 schema:name Fluorescein Angiography
    190 rdf:type schema:DefinedTerm
    191 Nf52669481214408599fc777b3cb3aba0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    192 schema:name Adult
    193 rdf:type schema:DefinedTerm
    194 Nff7d9f6e128843cbb6481024f15534d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    195 schema:name Coloring Agents
    196 rdf:type schema:DefinedTerm
    197 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    198 schema:name Medical and Health Sciences
    199 rdf:type schema:DefinedTerm
    200 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    201 schema:name Oncology and Carcinogenesis
    202 rdf:type schema:DefinedTerm
    203 sg:journal.1086446 schema:issn 0364-2313
    204 1432-2323
    205 schema:name World Journal of Surgery
    206 schema:publisher Springer Nature
    207 rdf:type schema:Periodical
    208 sg:person.010335623561.62 schema:affiliation grid-institutes:grid.412406.5
    209 schema:familyName Fujino
    210 schema:givenName Masafumi
    211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010335623561.62
    212 rdf:type schema:Person
    213 sg:person.01103413111.45 schema:affiliation grid-institutes:grid.412406.5
    214 schema:familyName Shimizu
    215 schema:givenName Hiroaki
    216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103413111.45
    217 rdf:type schema:Person
    218 sg:person.01133656514.23 schema:affiliation grid-institutes:None
    219 schema:familyName Mori
    220 schema:givenName Mikito
    221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133656514.23
    222 rdf:type schema:Person
    223 sg:person.01213167443.37 schema:affiliation grid-institutes:grid.412406.5
    224 schema:familyName Kosugi
    225 schema:givenName Chihiro
    226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213167443.37
    227 rdf:type schema:Person
    228 sg:person.01245236012.98 schema:affiliation grid-institutes:None
    229 schema:familyName Narushima
    230 schema:givenName Kazuo
    231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245236012.98
    232 rdf:type schema:Person
    233 sg:person.01257014672.12 schema:affiliation grid-institutes:None
    234 schema:familyName Hirano
    235 schema:givenName Atsushi
    236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257014672.12
    237 rdf:type schema:Person
    238 sg:person.01361326355.05 schema:affiliation grid-institutes:grid.412406.5
    239 schema:familyName Shuto
    240 schema:givenName Kiyohiko
    241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361326355.05
    242 rdf:type schema:Person
    243 sg:person.0647155176.80 schema:affiliation grid-institutes:grid.412406.5
    244 schema:familyName Koda
    245 schema:givenName Keiji
    246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647155176.80
    247 rdf:type schema:Person
    248 sg:person.0647637172.13 schema:affiliation grid-institutes:grid.412406.5
    249 schema:familyName Yamazaki
    250 schema:givenName Masato
    251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647637172.13
    252 rdf:type schema:Person
    253 sg:person.0700157264.27 schema:affiliation grid-institutes:grid.412406.5
    254 schema:familyName Hosokawa
    255 schema:givenName Isamu
    256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700157264.27
    257 rdf:type schema:Person
    258 sg:pub.10.1007/978-3-319-40618-3_17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1087262094
    259 https://doi.org/10.1007/978-3-319-40618-3_17
    260 rdf:type schema:CreativeWork
    261 sg:pub.10.1007/bf00292253 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031031741
    262 https://doi.org/10.1007/bf00292253
    263 rdf:type schema:CreativeWork
    264 sg:pub.10.1007/s00384-006-0221-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004968252
    265 https://doi.org/10.1007/s00384-006-0221-7
    266 rdf:type schema:CreativeWork
    267 sg:pub.10.1007/s00384-009-0658-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018409767
    268 https://doi.org/10.1007/s00384-009-0658-6
    269 rdf:type schema:CreativeWork
    270 sg:pub.10.1007/s00423-016-1400-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024297110
    271 https://doi.org/10.1007/s00423-016-1400-9
    272 rdf:type schema:CreativeWork
    273 sg:pub.10.1007/s00464-010-1493-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033808049
    274 https://doi.org/10.1007/s00464-010-1493-0
    275 rdf:type schema:CreativeWork
    276 sg:pub.10.1007/s00464-016-5064-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014302636
    277 https://doi.org/10.1007/s00464-016-5064-x
    278 rdf:type schema:CreativeWork
    279 sg:pub.10.1007/s00464-016-5181-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027260581
    280 https://doi.org/10.1007/s00464-016-5181-6
    281 rdf:type schema:CreativeWork
    282 sg:pub.10.1007/s10388-011-0291-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020889898
    283 https://doi.org/10.1007/s10388-011-0291-7
    284 rdf:type schema:CreativeWork
    285 sg:pub.10.1007/s10388-017-0585-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090281791
    286 https://doi.org/10.1007/s10388-017-0585-5
    287 rdf:type schema:CreativeWork
    288 sg:pub.10.1007/s11605-016-3195-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1001396468
    289 https://doi.org/10.1007/s11605-016-3195-y
    290 rdf:type schema:CreativeWork
    291 sg:pub.10.1007/s11605-016-3255-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039755023
    292 https://doi.org/10.1007/s11605-016-3255-3
    293 rdf:type schema:CreativeWork
    294 sg:pub.10.1007/s11605-018-3787-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103995280
    295 https://doi.org/10.1007/s11605-018-3787-9
    296 rdf:type schema:CreativeWork
    297 sg:pub.10.1186/1477-7819-9-55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013805157
    298 https://doi.org/10.1186/1477-7819-9-55
    299 rdf:type schema:CreativeWork
    300 sg:pub.10.1245/s10434-015-4743-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028715455
    301 https://doi.org/10.1245/s10434-015-4743-5
    302 rdf:type schema:CreativeWork
    303 grid-institutes:None schema:alternateName Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare Ichikawa Hospital, 6-1-14 Kounodai, 272-0827, Ichikawa, Chiba, Japan
    304 schema:name Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare Ichikawa Hospital, 6-1-14 Kounodai, 272-0827, Ichikawa, Chiba, Japan
    305 Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan
    306 rdf:type schema:Organization
    307 grid-institutes:grid.412406.5 schema:alternateName Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan
    308 schema:name Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara, Chiba, Japan
    309 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...