High-Dose RAI Therapy Justified by Pathological N1a Disease Revealed by Prophylactic Central Neck Dissection for cN0 Papillary Thyroid Cancer Patients: ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-05

AUTHORS

Lan Wei, Lin Bai, Lina Zhao, Tianyu Yu, Qingjie Ma, Bin Ji

ABSTRACT

OBJECTIVE: One of the presumed advantages of prophylactic central neck dissection (pCND) is offering staging basis for more aggressive radioactive iodine (RAI) therapy, which postulates the necessity of high dose for treatment efficacy. The present study aims to compare the effectiveness between low-dose and high-dose RAI in a select cohort of cN0 papillary thyroid cancer (PTC) patients with pathological N1a (pN1a) disease revealed by pCND in terms of ablation rate and response to therapy. The frequency of short-term adverse effects between the two groups was also compared. PATIENTS AND METHODS: From January 2014 to April 2016, cN0 PTC patients with pN1a disease revealed by pCND in our hospital were retrospectively reviewed. Patients with other indications for high-dose RAI, such as the presence of extrathyroidal extension, vascular invasion or suspicions of distant metastasis, were excluded. For the included patients, high dose (3700 MBq) was administered between January 2014 and August 2015 and low dose (1110 MBq) between August 2015 and April 2016. Ablation assessment was performed 6 months after RAI therapy. Response evaluation after RAI therapy was performed after 46.3 ± 9.5 months for high-dose group and 29.1 ± 2.6 months for low-dose group. All patients were also evaluated for short-term adverse effects 24 and 72 hours after RAI administration. RESULTS: A total of 84 patients were enrolled. Among them, 42 were in the high-dose group and the other 42 in the low-dose group. There was no significant difference in ablation rate (P = 0.7707) and response to RAI therapy (P = 0.6454) between the two groups. Twenty-four hours after RAI administration, neck pain and swelling (33.3% VS. 11.9%; P = 0.0372) and gastrointestinal discomfort (45.2% vs. 21.4%; P = 0.0373) were significantly more frequent in the high-dose group. CONCLUSION: High-dose RAI therapy, with higher frequency of short-term adverse effects, appears to be not superior to low-dose RAI therapy for cN0 PTC patients with pN1a disease revealed by pCND to achieve better response to therapy. Further randomized studies with larger series of patients and longer follow-up duration, especially with the low-dose group, are needed to validate our results. More... »

PAGES

1256-1263

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00268-019-04924-0

DOI

http://dx.doi.org/10.1007/s00268-019-04924-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111664560

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30684002


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "China-Japan Friendship Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nuclear Medicine, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin Province, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wei", 
        "givenName": "Lan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "China-Japan Friendship Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nuclear Medicine, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin Province, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bai", 
        "givenName": "Lin", 
        "id": "sg:person.0661346507.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661346507.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "China-Japan Friendship Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin Province, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhao", 
        "givenName": "Lina", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "China-Japan Friendship Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin Province, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yu", 
        "givenName": "Tianyu", 
        "id": "sg:person.015352566231.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015352566231.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "China-Japan Friendship Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nuclear Medicine, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin Province, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ma", 
        "givenName": "Qingjie", 
        "id": "sg:person.01043710307.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043710307.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "China-Japan Friendship Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nuclear Medicine, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin Province, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ji", 
        "givenName": "Bin", 
        "id": "sg:person.0755011056.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755011056.43"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.surg.2015.08.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001758894"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.surg.2015.08.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001758894"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1108586", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005286121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2015.0020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007626247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2009.0110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018764357"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31824b7b68", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021644524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31824b7b68", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021644524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31824b7b68", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021644524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-013-3258-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022113075", 
          "https://doi.org/10.1245/s10434-013-3258-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-12-0954", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022751879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-12-0744", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025043846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00405-014-3453-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025513689", 
          "https://doi.org/10.1007/s00405-014-3453-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00405-014-3453-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025513689", 
          "https://doi.org/10.1007/s00405-014-3453-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2009.0159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029587518"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4103/1450-1147.174703", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037612770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/0284186x.2012.742959", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039527185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jamcollsurg.2016.02.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040330267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jamcollsurg.2016.02.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040330267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-15-0481", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049004622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-15-0481", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049004622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2012.0043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2012.0043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2005-0285", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064288355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2014-1199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064295008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mnm.0000000000000666", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084195603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mnm.0000000000000666", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084195603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mnm.0000000000000666", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084195603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2015.0658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084781281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2015.0658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084781281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2016.0655", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086037993"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mnm.0000000000000756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091929781"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mnm.0000000000000756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091929781"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mnm.0000000000000756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091929781"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.21053/ceo.2017.00472", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092246461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-018-6528-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104137900", 
          "https://doi.org/10.1245/s10434-018-6528-0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-05", 
    "datePublishedReg": "2019-05-01", 
    "description": "OBJECTIVE: One of the presumed advantages of prophylactic central neck dissection (pCND) is offering staging basis for more aggressive radioactive iodine (RAI) therapy, which postulates the necessity of high dose for treatment efficacy. The present study aims to compare the effectiveness between low-dose and high-dose RAI in a select cohort of cN0 papillary thyroid cancer (PTC) patients with pathological N1a (pN1a) disease revealed by pCND in terms of ablation rate and response to therapy. The frequency of short-term adverse effects between the two groups was also compared.\nPATIENTS AND METHODS: From January 2014 to April 2016, cN0 PTC patients with pN1a disease revealed by pCND in our hospital were retrospectively reviewed. Patients with other indications for high-dose RAI, such as the presence of extrathyroidal extension, vascular invasion or suspicions of distant metastasis, were excluded. For the included patients, high dose (3700 MBq) was administered between January 2014 and August 2015 and low dose (1110 MBq) between August 2015 and April 2016. Ablation assessment was performed 6 months after RAI therapy. Response evaluation after RAI therapy was performed after 46.3 \u00b1 9.5 months for high-dose group and 29.1 \u00b1 2.6 months for low-dose group. All patients were also evaluated for short-term adverse effects 24 and 72 hours after RAI administration.\nRESULTS: A total of 84 patients were enrolled. Among them, 42 were in the high-dose group and the other 42 in the low-dose group. There was no significant difference in ablation rate (P = 0.7707) and response to RAI therapy (P = 0.6454) between the two groups. Twenty-four hours after RAI administration, neck pain and swelling (33.3% VS. 11.9%; P = 0.0372) and gastrointestinal discomfort (45.2% vs. 21.4%; P = 0.0373) were significantly more frequent in the high-dose group.\nCONCLUSION: High-dose RAI therapy, with higher frequency of short-term adverse effects, appears to be not superior to low-dose RAI therapy for cN0 PTC patients with pN1a disease revealed by pCND to achieve better response to therapy. Further randomized studies with larger series of patients and longer follow-up duration, especially with the low-dose group, are needed to validate our results.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00268-019-04924-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1086446", 
        "issn": [
          "0364-2313", 
          "1432-2323"
        ], 
        "name": "World Journal of Surgery", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "43"
      }
    ], 
    "name": "High-Dose RAI Therapy Justified by Pathological N1a Disease Revealed by Prophylactic Central Neck Dissection for cN0 Papillary Thyroid Cancer Patients: Is it Superior to Low-Dose RAI Therapy?", 
    "pagination": "1256-1263", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f688aa9e1999463ddb9169192bc2c5986c46a30d72a85a50f4722dc9a122efcd"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30684002"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7704052"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00268-019-04924-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1111664560"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00268-019-04924-0", 
      "https://app.dimensions.ai/details/publication/pub.1111664560"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:17", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000372_0000000372/records_117092_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00268-019-04924-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00268-019-04924-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00268-019-04924-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00268-019-04924-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00268-019-04924-0'


 

This table displays all metadata directly associated to this object as RDF triples.

175 TRIPLES      21 PREDICATES      52 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00268-019-04924-0 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Ndac2c6bb868f4ac9929543d3ebd35a8d
4 schema:citation sg:pub.10.1007/s00405-014-3453-0
5 sg:pub.10.1245/s10434-013-3258-1
6 sg:pub.10.1245/s10434-018-6528-0
7 https://doi.org/10.1016/j.jamcollsurg.2016.02.001
8 https://doi.org/10.1016/j.surg.2015.08.033
9 https://doi.org/10.1056/nejmoa1108586
10 https://doi.org/10.1089/thy.2009.0110
11 https://doi.org/10.1089/thy.2009.0159
12 https://doi.org/10.1089/thy.2012.0043
13 https://doi.org/10.1089/thy.2015.0020
14 https://doi.org/10.1089/thy.2015.0658
15 https://doi.org/10.1089/thy.2016.0655
16 https://doi.org/10.1097/mnm.0000000000000666
17 https://doi.org/10.1097/mnm.0000000000000756
18 https://doi.org/10.1097/sla.0b013e31824b7b68
19 https://doi.org/10.1210/jc.2005-0285
20 https://doi.org/10.1210/jc.2014-1199
21 https://doi.org/10.1530/eje-12-0744
22 https://doi.org/10.1530/eje-12-0954
23 https://doi.org/10.1530/eje-15-0481
24 https://doi.org/10.21053/ceo.2017.00472
25 https://doi.org/10.3109/0284186x.2012.742959
26 https://doi.org/10.4103/1450-1147.174703
27 schema:datePublished 2019-05
28 schema:datePublishedReg 2019-05-01
29 schema:description OBJECTIVE: One of the presumed advantages of prophylactic central neck dissection (pCND) is offering staging basis for more aggressive radioactive iodine (RAI) therapy, which postulates the necessity of high dose for treatment efficacy. The present study aims to compare the effectiveness between low-dose and high-dose RAI in a select cohort of cN0 papillary thyroid cancer (PTC) patients with pathological N1a (pN1a) disease revealed by pCND in terms of ablation rate and response to therapy. The frequency of short-term adverse effects between the two groups was also compared. PATIENTS AND METHODS: From January 2014 to April 2016, cN0 PTC patients with pN1a disease revealed by pCND in our hospital were retrospectively reviewed. Patients with other indications for high-dose RAI, such as the presence of extrathyroidal extension, vascular invasion or suspicions of distant metastasis, were excluded. For the included patients, high dose (3700 MBq) was administered between January 2014 and August 2015 and low dose (1110 MBq) between August 2015 and April 2016. Ablation assessment was performed 6 months after RAI therapy. Response evaluation after RAI therapy was performed after 46.3 ± 9.5 months for high-dose group and 29.1 ± 2.6 months for low-dose group. All patients were also evaluated for short-term adverse effects 24 and 72 hours after RAI administration. RESULTS: A total of 84 patients were enrolled. Among them, 42 were in the high-dose group and the other 42 in the low-dose group. There was no significant difference in ablation rate (P = 0.7707) and response to RAI therapy (P = 0.6454) between the two groups. Twenty-four hours after RAI administration, neck pain and swelling (33.3% VS. 11.9%; P = 0.0372) and gastrointestinal discomfort (45.2% vs. 21.4%; P = 0.0373) were significantly more frequent in the high-dose group. CONCLUSION: High-dose RAI therapy, with higher frequency of short-term adverse effects, appears to be not superior to low-dose RAI therapy for cN0 PTC patients with pN1a disease revealed by pCND to achieve better response to therapy. Further randomized studies with larger series of patients and longer follow-up duration, especially with the low-dose group, are needed to validate our results.
30 schema:genre research_article
31 schema:inLanguage en
32 schema:isAccessibleForFree false
33 schema:isPartOf N2aacb63cab0949a59b0d76c4e4ce8d38
34 N90a44ae6adb64b3bbedc8d1c67d5af19
35 sg:journal.1086446
36 schema:name High-Dose RAI Therapy Justified by Pathological N1a Disease Revealed by Prophylactic Central Neck Dissection for cN0 Papillary Thyroid Cancer Patients: Is it Superior to Low-Dose RAI Therapy?
37 schema:pagination 1256-1263
38 schema:productId N3acc9325868a49f0b504a9401f04d088
39 N5cda65ebc4784854913ac4048e837d41
40 N9ac88baa0e8d4b919baed7582e4a65f4
41 N9bc38acd556e473f81eed67b0a261c2a
42 Na815835e587b42c4a78cdcf7a68c36c2
43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111664560
44 https://doi.org/10.1007/s00268-019-04924-0
45 schema:sdDatePublished 2019-04-11T14:17
46 schema:sdLicense https://scigraph.springernature.com/explorer/license/
47 schema:sdPublisher N37e9853e65f8426eab5177a9072f847d
48 schema:url https://link.springer.com/10.1007%2Fs00268-019-04924-0
49 sgo:license sg:explorer/license/
50 sgo:sdDataset articles
51 rdf:type schema:ScholarlyArticle
52 N1b29ab94e6eb4639912fe24041020186 rdf:first sg:person.01043710307.59
53 rdf:rest Ndf3a011ae9a54a61935315974b5f8314
54 N25fac706c3d14d9abcdec4addbc79f78 schema:affiliation https://www.grid.ac/institutes/grid.415954.8
55 schema:familyName Zhao
56 schema:givenName Lina
57 rdf:type schema:Person
58 N2aacb63cab0949a59b0d76c4e4ce8d38 schema:volumeNumber 43
59 rdf:type schema:PublicationVolume
60 N2d7334f4f1a64d13af37b32f12f4a43c rdf:first N25fac706c3d14d9abcdec4addbc79f78
61 rdf:rest N8c9cdeb42454443b95bd1d33c104685a
62 N37e9853e65f8426eab5177a9072f847d schema:name Springer Nature - SN SciGraph project
63 rdf:type schema:Organization
64 N3acc9325868a49f0b504a9401f04d088 schema:name doi
65 schema:value 10.1007/s00268-019-04924-0
66 rdf:type schema:PropertyValue
67 N5cda65ebc4784854913ac4048e837d41 schema:name dimensions_id
68 schema:value pub.1111664560
69 rdf:type schema:PropertyValue
70 N8c9cdeb42454443b95bd1d33c104685a rdf:first sg:person.015352566231.04
71 rdf:rest N1b29ab94e6eb4639912fe24041020186
72 N90a44ae6adb64b3bbedc8d1c67d5af19 schema:issueNumber 5
73 rdf:type schema:PublicationIssue
74 N9ac88baa0e8d4b919baed7582e4a65f4 schema:name readcube_id
75 schema:value f688aa9e1999463ddb9169192bc2c5986c46a30d72a85a50f4722dc9a122efcd
76 rdf:type schema:PropertyValue
77 N9bc38acd556e473f81eed67b0a261c2a schema:name nlm_unique_id
78 schema:value 7704052
79 rdf:type schema:PropertyValue
80 N9f7dace95a1b448b8e6fc21ccd9732f6 rdf:first sg:person.0661346507.89
81 rdf:rest N2d7334f4f1a64d13af37b32f12f4a43c
82 Na815835e587b42c4a78cdcf7a68c36c2 schema:name pubmed_id
83 schema:value 30684002
84 rdf:type schema:PropertyValue
85 Ndac2c6bb868f4ac9929543d3ebd35a8d rdf:first Nf471c0785c9940e7ba54b3e97b1f1341
86 rdf:rest N9f7dace95a1b448b8e6fc21ccd9732f6
87 Ndf3a011ae9a54a61935315974b5f8314 rdf:first sg:person.0755011056.43
88 rdf:rest rdf:nil
89 Nf471c0785c9940e7ba54b3e97b1f1341 schema:affiliation https://www.grid.ac/institutes/grid.415954.8
90 schema:familyName Wei
91 schema:givenName Lan
92 rdf:type schema:Person
93 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
94 schema:name Medical and Health Sciences
95 rdf:type schema:DefinedTerm
96 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
97 schema:name Clinical Sciences
98 rdf:type schema:DefinedTerm
99 sg:journal.1086446 schema:issn 0364-2313
100 1432-2323
101 schema:name World Journal of Surgery
102 rdf:type schema:Periodical
103 sg:person.01043710307.59 schema:affiliation https://www.grid.ac/institutes/grid.415954.8
104 schema:familyName Ma
105 schema:givenName Qingjie
106 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043710307.59
107 rdf:type schema:Person
108 sg:person.015352566231.04 schema:affiliation https://www.grid.ac/institutes/grid.415954.8
109 schema:familyName Yu
110 schema:givenName Tianyu
111 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015352566231.04
112 rdf:type schema:Person
113 sg:person.0661346507.89 schema:affiliation https://www.grid.ac/institutes/grid.415954.8
114 schema:familyName Bai
115 schema:givenName Lin
116 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661346507.89
117 rdf:type schema:Person
118 sg:person.0755011056.43 schema:affiliation https://www.grid.ac/institutes/grid.415954.8
119 schema:familyName Ji
120 schema:givenName Bin
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755011056.43
122 rdf:type schema:Person
123 sg:pub.10.1007/s00405-014-3453-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025513689
124 https://doi.org/10.1007/s00405-014-3453-0
125 rdf:type schema:CreativeWork
126 sg:pub.10.1245/s10434-013-3258-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022113075
127 https://doi.org/10.1245/s10434-013-3258-1
128 rdf:type schema:CreativeWork
129 sg:pub.10.1245/s10434-018-6528-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1104137900
130 https://doi.org/10.1245/s10434-018-6528-0
131 rdf:type schema:CreativeWork
132 https://doi.org/10.1016/j.jamcollsurg.2016.02.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040330267
133 rdf:type schema:CreativeWork
134 https://doi.org/10.1016/j.surg.2015.08.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001758894
135 rdf:type schema:CreativeWork
136 https://doi.org/10.1056/nejmoa1108586 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005286121
137 rdf:type schema:CreativeWork
138 https://doi.org/10.1089/thy.2009.0110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018764357
139 rdf:type schema:CreativeWork
140 https://doi.org/10.1089/thy.2009.0159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029587518
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1089/thy.2012.0043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321414
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1089/thy.2015.0020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007626247
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1089/thy.2015.0658 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084781281
147 rdf:type schema:CreativeWork
148 https://doi.org/10.1089/thy.2016.0655 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086037993
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1097/mnm.0000000000000666 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084195603
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1097/mnm.0000000000000756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091929781
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1097/sla.0b013e31824b7b68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021644524
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1210/jc.2005-0285 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064288355
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1210/jc.2014-1199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064295008
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1530/eje-12-0744 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025043846
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1530/eje-12-0954 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022751879
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1530/eje-15-0481 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049004622
165 rdf:type schema:CreativeWork
166 https://doi.org/10.21053/ceo.2017.00472 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092246461
167 rdf:type schema:CreativeWork
168 https://doi.org/10.3109/0284186x.2012.742959 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039527185
169 rdf:type schema:CreativeWork
170 https://doi.org/10.4103/1450-1147.174703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037612770
171 rdf:type schema:CreativeWork
172 https://www.grid.ac/institutes/grid.415954.8 schema:alternateName China-Japan Friendship Hospital
173 schema:name Department of Nuclear Medicine, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin Province, China
174 Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin Province, China
175 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...