Impact of Surgery on Quality of Life in Patients with Hepatocellular Carcinoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-12-05

AUTHORS

Yoshihiro Mise, Shouichi Satou, Takeaki Ishizawa, Junichi Kaneko, Taku Aoki, Kiyoshi Hasegawa, Yasuhiko Sugawara, Masatoshi Makuuchi, Norihiro Kokudo

ABSTRACT

BackgroundLiver resection is the mainstay of curative treatment for localized hepatocellular carcinoma (HCC). However, the impact of surgery for HCC on quality of life (QOL) has not been well assessed.MethodsHealth-related QOL was assessed using the Short Form-36 questionnaire in 108 patients who underwent a liver resection for HCC between January 2004 and January 2008. The QOL assessment was scheduled before and every 3 months after the operation. Patients were divided into two groups based on patient-, tumor-, and surgery-related variables. The physical component summary (PCS) and mental component summary (MCS) were compared between the two groups.ResultsAltogether, 69 patients (64 %) completed the consecutive QOL assessments until 6 months after surgery. At 3 months, the PCS scores were significantly lower for women and for patients who had undergone thoracotomy than among men (p = 0.010) and patients who had not undergone thoracotomy (p = 0.048), respectively. No significant differences in any of the PCS scores were observed at 6 months. No significant differences in the MCS scores were observed between the groups throughout the investigation, and improvement relative to the preoperative status was observed at 6 months.ConclusionsPhysical impairments in the QOL after surgery had returned to the baseline at 6 months, and the postoperative mental QOL improved relative to the preoperative state. The surgical candidates were expected to have a satisfactory QOL regardless of the preoperative status and surgical outcomes. A thoracoabdominal approach had a transient negative impact on the physical health status. More... »

PAGES

958-967

References to SciGraph publications

  • 2011-05-27. Gender differences and determinants of health related quality of life in coronary patients: a follow-up study in BMC CARDIOVASCULAR DISORDERS
  • 2012-03-07. Long-Term Outcomes of Repeat Hepatic Resection in Patients with Recurrent Hepatocellular Carcinoma and Analysis of Recurrent Types and Their Prognosis: A Single-Center Experience in China in ANNALS OF SURGICAL ONCOLOGY
  • 1992-06. Report from a National Cancer Institute (USA) workshop on quality of life assessment in cancer clinical trials in QUALITY OF LIFE RESEARCH
  • 2011-08-17. Repeat treatment for recurrent hepatocellular carcinoma: is it validated? in LANGENBECK'S ARCHIVES OF SURGERY
  • 2005-03. Gender differences in health-related quality of life in patients with HIV/AIDS in QUALITY OF LIFE RESEARCH
  • 2002-05. Gender differences in the symptoms and physical and mental well-being of dyspeptics: A population based study in QUALITY OF LIFE RESEARCH
  • 2008-01-16. Changes in quality of life and its related factors in liver cancer patients receiving stereotactic radiation therapy in SUPPORTIVE CARE IN CANCER
  • 2006-01-24. Gender differences in health-related quality of life of adolescents with cystic fibrosis in HEALTH AND QUALITY OF LIFE OUTCOMES
  • 2011-10-27. Validation of Biological and Clinical Outcome Between with and without Thoracotomy in Liver Resection: A Matched Cohort Study in WORLD JOURNAL OF SURGERY
  • 2006-11-17. Quality of life after radiofrequency ablation combined with transcatheter arterial chemoembolization for hepatocellular carcinoma: comparison with transcatheter arterial chemoembolization alone in QUALITY OF LIFE RESEARCH
  • 2010-07-09. Meta-analysis of radiofrequency ablation versus hepatic resection for small hepatocellular carcinoma in BMC GASTROENTEROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00268-013-2342-9

    DOI

    http://dx.doi.org/10.1007/s00268-013-2342-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1018791851

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/24305919


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged, 80 and over", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoma, Hepatocellular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Follow-Up Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hepatectomy", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Liver Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Quality of Life", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Surveys and Questionnaires", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Treatment Outcome", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.26999.3d", 
              "name": [
                "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mise", 
            "givenName": "Yoshihiro", 
            "id": "sg:person.0626665021.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626665021.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.26999.3d", 
              "name": [
                "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Satou", 
            "givenName": "Shouichi", 
            "id": "sg:person.0637447533.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637447533.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.26999.3d", 
              "name": [
                "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ishizawa", 
            "givenName": "Takeaki", 
            "id": "sg:person.01267647573.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267647573.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.26999.3d", 
              "name": [
                "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kaneko", 
            "givenName": "Junichi", 
            "id": "sg:person.0661346015.67", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661346015.67"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.26999.3d", 
              "name": [
                "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Aoki", 
            "givenName": "Taku", 
            "id": "sg:person.010513773012.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010513773012.24"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.26999.3d", 
              "name": [
                "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hasegawa", 
            "givenName": "Kiyoshi", 
            "id": "sg:person.01065410232.04", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065410232.04"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.26999.3d", 
              "name": [
                "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sugawara", 
            "givenName": "Yasuhiko", 
            "id": "sg:person.01222410315.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222410315.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Hepato-Biliary-Pancreatic Surgery, Japanese Red Cross Medical Center, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.414929.3", 
              "name": [
                "Department of Hepato-Biliary-Pancreatic Surgery, Japanese Red Cross Medical Center, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Makuuchi", 
            "givenName": "Masatoshi", 
            "id": "sg:person.01133222703.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133222703.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
              "id": "http://www.grid.ac/institutes/grid.26999.3d", 
              "name": [
                "Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kokudo", 
            "givenName": "Norihiro", 
            "id": "sg:person.0735351167.82", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735351167.82"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1186/1471-230x-10-78", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006659197", 
              "https://doi.org/10.1186/1471-230x-10-78"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1245/s10434-012-2269-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037676641", 
              "https://doi.org/10.1245/s10434-012-2269-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11136-006-9133-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038681970", 
              "https://doi.org/10.1007/s11136-006-9133-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1015239020403", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009117599", 
              "https://doi.org/10.1023/a:1015239020403"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00268-011-1320-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003923011", 
              "https://doi.org/10.1007/s00268-011-1320-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11136-004-4693-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049790292", 
              "https://doi.org/10.1007/s11136-004-4693-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2261-11-24", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034355439", 
              "https://doi.org/10.1186/1471-2261-11-24"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00423-011-0837-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009255762", 
              "https://doi.org/10.1007/s00423-011-0837-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00635619", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003376544", 
              "https://doi.org/10.1007/bf00635619"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00520-007-0384-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035001534", 
              "https://doi.org/10.1007/s00520-007-0384-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1477-7525-4-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020545916", 
              "https://doi.org/10.1186/1477-7525-4-5"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2013-12-05", 
        "datePublishedReg": "2013-12-05", 
        "description": "BackgroundLiver resection is the mainstay of curative treatment for localized hepatocellular carcinoma (HCC). However, the impact of surgery for HCC on quality of life (QOL) has not been well assessed.MethodsHealth-related QOL was assessed using the Short Form-36 questionnaire in 108 patients who underwent a liver resection for HCC between January 2004 and January 2008. The QOL assessment was scheduled before and every 3\u00a0months after the operation. Patients were divided into two groups based on patient-, tumor-, and surgery-related variables. The physical component summary (PCS) and mental component summary (MCS) were compared between the two groups.ResultsAltogether, 69 patients (64\u00a0%) completed the consecutive QOL assessments until 6\u00a0months after surgery. At 3\u00a0months, the PCS scores were significantly lower for women and for patients who had undergone thoracotomy than among men (p\u00a0=\u00a00.010) and patients who had not undergone thoracotomy (p\u00a0=\u00a00.048), respectively. No significant differences in any of the PCS scores were observed at 6\u00a0months. No significant differences in the MCS scores were observed between the groups throughout the investigation, and improvement relative to the preoperative status was observed at 6\u00a0months.ConclusionsPhysical impairments in the QOL after surgery had returned to the baseline at 6\u00a0months, and the postoperative mental QOL improved relative to the preoperative state. The surgical candidates were expected to have a satisfactory QOL regardless of the preoperative status and surgical outcomes. A thoracoabdominal approach had a transient negative impact on the physical health status.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s00268-013-2342-9", 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.6067128", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1086446", 
            "issn": [
              "0364-2313", 
              "1432-2323"
            ], 
            "name": "World Journal of Surgery", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "4", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "38"
          }
        ], 
        "keywords": [
          "quality of life", 
          "impact of surgery", 
          "physical component summary", 
          "mental component summary", 
          "hepatocellular carcinoma", 
          "preoperative status", 
          "component summary", 
          "PCS scores", 
          "QoL assessment", 
          "Short Form-36 questionnaire", 
          "mental QOL", 
          "satisfactory QOL", 
          "surgery-related variables", 
          "physical health status", 
          "significant differences", 
          "transient negative impact", 
          "BackgroundLiver resection", 
          "liver resection", 
          "surgical candidates", 
          "preoperative state", 
          "curative treatment", 
          "MCS scores", 
          "surgical outcomes", 
          "thoracoabdominal approach", 
          "patients", 
          "health status", 
          "surgery", 
          "months", 
          "thoracotomy", 
          "resection", 
          "carcinoma", 
          "scores", 
          "status", 
          "group", 
          "ResultsAltogether", 
          "MethodsHealth", 
          "tumors", 
          "mainstay", 
          "impairment", 
          "baseline", 
          "women", 
          "assessment", 
          "outcomes", 
          "men", 
          "treatment", 
          "differences", 
          "summary", 
          "life", 
          "questionnaire", 
          "negative impact", 
          "impact", 
          "quality", 
          "improvement", 
          "candidates", 
          "variables", 
          "investigation", 
          "operation", 
          "approach", 
          "state"
        ], 
        "name": "Impact of Surgery on Quality of Life in Patients with Hepatocellular Carcinoma", 
        "pagination": "958-967", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1018791851"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00268-013-2342-9"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "24305919"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00268-013-2342-9", 
          "https://app.dimensions.ai/details/publication/pub.1018791851"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-12-01T06:31", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_609.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s00268-013-2342-9"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00268-013-2342-9'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00268-013-2342-9'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00268-013-2342-9'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00268-013-2342-9'


     

    This table displays all metadata directly associated to this object as RDF triples.

    285 TRIPLES      21 PREDICATES      110 URIs      91 LITERALS      22 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00268-013-2342-9 schema:about N0a7e1273da9b4828a6098ea355799132
    2 N19cb473e789a407b8ec1593263db0f97
    3 N1d45b10130614c36aff1333a33f49351
    4 N1fd101e1dc1f43f28aeda0cd95b17611
    5 N2a6783aec6f946eebca464fa05ea6884
    6 N5a610096049647a4849805cf2d971563
    7 N6bc0d62c53f54c88a2ae592488e2afb1
    8 N7774693b9e674a0ea66eed460428ff24
    9 N7e2528402a02439a9ee7ab7a0f38fdfd
    10 N848de9c4cfaa465aba72426b3677c3dd
    11 N85f7890a111343e7b34fb42da2546cae
    12 Nad112a7bf1014a468780ce58ad319c77
    13 Nc6b05a8ec24440b08798a9f02671bf70
    14 Nd7c8e9dfc3b84a12bfd8fd05272d6c37
    15 Nf7945b68b6844e929a0b8c12f1f4a019
    16 anzsrc-for:11
    17 anzsrc-for:1112
    18 schema:author N997786440b3e4d4e8b7e3b2be042da8c
    19 schema:citation sg:pub.10.1007/bf00635619
    20 sg:pub.10.1007/s00268-011-1320-3
    21 sg:pub.10.1007/s00423-011-0837-0
    22 sg:pub.10.1007/s00520-007-0384-y
    23 sg:pub.10.1007/s11136-004-4693-z
    24 sg:pub.10.1007/s11136-006-9133-9
    25 sg:pub.10.1023/a:1015239020403
    26 sg:pub.10.1186/1471-2261-11-24
    27 sg:pub.10.1186/1471-230x-10-78
    28 sg:pub.10.1186/1477-7525-4-5
    29 sg:pub.10.1245/s10434-012-2269-7
    30 schema:datePublished 2013-12-05
    31 schema:datePublishedReg 2013-12-05
    32 schema:description BackgroundLiver resection is the mainstay of curative treatment for localized hepatocellular carcinoma (HCC). However, the impact of surgery for HCC on quality of life (QOL) has not been well assessed.MethodsHealth-related QOL was assessed using the Short Form-36 questionnaire in 108 patients who underwent a liver resection for HCC between January 2004 and January 2008. The QOL assessment was scheduled before and every 3 months after the operation. Patients were divided into two groups based on patient-, tumor-, and surgery-related variables. The physical component summary (PCS) and mental component summary (MCS) were compared between the two groups.ResultsAltogether, 69 patients (64 %) completed the consecutive QOL assessments until 6 months after surgery. At 3 months, the PCS scores were significantly lower for women and for patients who had undergone thoracotomy than among men (p = 0.010) and patients who had not undergone thoracotomy (p = 0.048), respectively. No significant differences in any of the PCS scores were observed at 6 months. No significant differences in the MCS scores were observed between the groups throughout the investigation, and improvement relative to the preoperative status was observed at 6 months.ConclusionsPhysical impairments in the QOL after surgery had returned to the baseline at 6 months, and the postoperative mental QOL improved relative to the preoperative state. The surgical candidates were expected to have a satisfactory QOL regardless of the preoperative status and surgical outcomes. A thoracoabdominal approach had a transient negative impact on the physical health status.
    33 schema:genre article
    34 schema:isAccessibleForFree false
    35 schema:isPartOf N80594655cc3240f39f463e87a3d078f2
    36 Nb9dd68c286fc4b50bc5115f1eac2468d
    37 sg:journal.1086446
    38 schema:keywords BackgroundLiver resection
    39 MCS scores
    40 MethodsHealth
    41 PCS scores
    42 QoL assessment
    43 ResultsAltogether
    44 Short Form-36 questionnaire
    45 approach
    46 assessment
    47 baseline
    48 candidates
    49 carcinoma
    50 component summary
    51 curative treatment
    52 differences
    53 group
    54 health status
    55 hepatocellular carcinoma
    56 impact
    57 impact of surgery
    58 impairment
    59 improvement
    60 investigation
    61 life
    62 liver resection
    63 mainstay
    64 men
    65 mental QOL
    66 mental component summary
    67 months
    68 negative impact
    69 operation
    70 outcomes
    71 patients
    72 physical component summary
    73 physical health status
    74 preoperative state
    75 preoperative status
    76 quality
    77 quality of life
    78 questionnaire
    79 resection
    80 satisfactory QOL
    81 scores
    82 significant differences
    83 state
    84 status
    85 summary
    86 surgery
    87 surgery-related variables
    88 surgical candidates
    89 surgical outcomes
    90 thoracoabdominal approach
    91 thoracotomy
    92 transient negative impact
    93 treatment
    94 tumors
    95 variables
    96 women
    97 schema:name Impact of Surgery on Quality of Life in Patients with Hepatocellular Carcinoma
    98 schema:pagination 958-967
    99 schema:productId N4a66fb46b1124172b2f49fd87c84657c
    100 Nc70dce14eba441e8b1cfa86074c540b7
    101 Nf5d07c79a4054e939267802a41026bbb
    102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018791851
    103 https://doi.org/10.1007/s00268-013-2342-9
    104 schema:sdDatePublished 2022-12-01T06:31
    105 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    106 schema:sdPublisher N2d5711191ec242e8921cbad3b9bc9583
    107 schema:url https://doi.org/10.1007/s00268-013-2342-9
    108 sgo:license sg:explorer/license/
    109 sgo:sdDataset articles
    110 rdf:type schema:ScholarlyArticle
    111 N0a7e1273da9b4828a6098ea355799132 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    112 schema:name Carcinoma, Hepatocellular
    113 rdf:type schema:DefinedTerm
    114 N19cb473e789a407b8ec1593263db0f97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    115 schema:name Liver Neoplasms
    116 rdf:type schema:DefinedTerm
    117 N1d45b10130614c36aff1333a33f49351 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    118 schema:name Prospective Studies
    119 rdf:type schema:DefinedTerm
    120 N1fd101e1dc1f43f28aeda0cd95b17611 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Middle Aged
    122 rdf:type schema:DefinedTerm
    123 N2785f5f5e1434335acbb9d60ac7089f7 rdf:first sg:person.010513773012.24
    124 rdf:rest N7a8c53c918c04865b888653ee222dc9a
    125 N29dbd8b1715944ebbed4e82daeb2bcd8 rdf:first sg:person.0661346015.67
    126 rdf:rest N2785f5f5e1434335acbb9d60ac7089f7
    127 N2a6783aec6f946eebca464fa05ea6884 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Aged, 80 and over
    129 rdf:type schema:DefinedTerm
    130 N2d5711191ec242e8921cbad3b9bc9583 schema:name Springer Nature - SN SciGraph project
    131 rdf:type schema:Organization
    132 N4a66fb46b1124172b2f49fd87c84657c schema:name pubmed_id
    133 schema:value 24305919
    134 rdf:type schema:PropertyValue
    135 N55da83cfcbb148f3b1ba89697712d03a rdf:first sg:person.0637447533.36
    136 rdf:rest N8f4c07d907324dcea9fe92ff7695d323
    137 N5a610096049647a4849805cf2d971563 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    138 schema:name Follow-Up Studies
    139 rdf:type schema:DefinedTerm
    140 N6bc0d62c53f54c88a2ae592488e2afb1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    141 schema:name Female
    142 rdf:type schema:DefinedTerm
    143 N7774693b9e674a0ea66eed460428ff24 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    144 schema:name Aged
    145 rdf:type schema:DefinedTerm
    146 N7a8c53c918c04865b888653ee222dc9a rdf:first sg:person.01065410232.04
    147 rdf:rest Nae2cf15b9e2143db82f4d5b14a0f052d
    148 N7e2528402a02439a9ee7ab7a0f38fdfd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    149 schema:name Adult
    150 rdf:type schema:DefinedTerm
    151 N80594655cc3240f39f463e87a3d078f2 schema:issueNumber 4
    152 rdf:type schema:PublicationIssue
    153 N848de9c4cfaa465aba72426b3677c3dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    154 schema:name Surveys and Questionnaires
    155 rdf:type schema:DefinedTerm
    156 N85f7890a111343e7b34fb42da2546cae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    157 schema:name Male
    158 rdf:type schema:DefinedTerm
    159 N8f4c07d907324dcea9fe92ff7695d323 rdf:first sg:person.01267647573.52
    160 rdf:rest N29dbd8b1715944ebbed4e82daeb2bcd8
    161 N940cfed25c9d4ebc881b4342140da724 rdf:first sg:person.0735351167.82
    162 rdf:rest rdf:nil
    163 N997786440b3e4d4e8b7e3b2be042da8c rdf:first sg:person.0626665021.66
    164 rdf:rest N55da83cfcbb148f3b1ba89697712d03a
    165 Nad112a7bf1014a468780ce58ad319c77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    166 schema:name Quality of Life
    167 rdf:type schema:DefinedTerm
    168 Nae2cf15b9e2143db82f4d5b14a0f052d rdf:first sg:person.01222410315.07
    169 rdf:rest Nbe3ed23ea1c64f4d99bc363d0f5c27b7
    170 Nb9dd68c286fc4b50bc5115f1eac2468d schema:volumeNumber 38
    171 rdf:type schema:PublicationVolume
    172 Nbe3ed23ea1c64f4d99bc363d0f5c27b7 rdf:first sg:person.01133222703.98
    173 rdf:rest N940cfed25c9d4ebc881b4342140da724
    174 Nc6b05a8ec24440b08798a9f02671bf70 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    175 schema:name Humans
    176 rdf:type schema:DefinedTerm
    177 Nc70dce14eba441e8b1cfa86074c540b7 schema:name doi
    178 schema:value 10.1007/s00268-013-2342-9
    179 rdf:type schema:PropertyValue
    180 Nd7c8e9dfc3b84a12bfd8fd05272d6c37 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    181 schema:name Hepatectomy
    182 rdf:type schema:DefinedTerm
    183 Nf5d07c79a4054e939267802a41026bbb schema:name dimensions_id
    184 schema:value pub.1018791851
    185 rdf:type schema:PropertyValue
    186 Nf7945b68b6844e929a0b8c12f1f4a019 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    187 schema:name Treatment Outcome
    188 rdf:type schema:DefinedTerm
    189 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    190 schema:name Medical and Health Sciences
    191 rdf:type schema:DefinedTerm
    192 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    193 schema:name Oncology and Carcinogenesis
    194 rdf:type schema:DefinedTerm
    195 sg:grant.6067128 http://pending.schema.org/fundedItem sg:pub.10.1007/s00268-013-2342-9
    196 rdf:type schema:MonetaryGrant
    197 sg:journal.1086446 schema:issn 0364-2313
    198 1432-2323
    199 schema:name World Journal of Surgery
    200 schema:publisher Springer Nature
    201 rdf:type schema:Periodical
    202 sg:person.010513773012.24 schema:affiliation grid-institutes:grid.26999.3d
    203 schema:familyName Aoki
    204 schema:givenName Taku
    205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010513773012.24
    206 rdf:type schema:Person
    207 sg:person.01065410232.04 schema:affiliation grid-institutes:grid.26999.3d
    208 schema:familyName Hasegawa
    209 schema:givenName Kiyoshi
    210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065410232.04
    211 rdf:type schema:Person
    212 sg:person.01133222703.98 schema:affiliation grid-institutes:grid.414929.3
    213 schema:familyName Makuuchi
    214 schema:givenName Masatoshi
    215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133222703.98
    216 rdf:type schema:Person
    217 sg:person.01222410315.07 schema:affiliation grid-institutes:grid.26999.3d
    218 schema:familyName Sugawara
    219 schema:givenName Yasuhiko
    220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222410315.07
    221 rdf:type schema:Person
    222 sg:person.01267647573.52 schema:affiliation grid-institutes:grid.26999.3d
    223 schema:familyName Ishizawa
    224 schema:givenName Takeaki
    225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267647573.52
    226 rdf:type schema:Person
    227 sg:person.0626665021.66 schema:affiliation grid-institutes:grid.26999.3d
    228 schema:familyName Mise
    229 schema:givenName Yoshihiro
    230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626665021.66
    231 rdf:type schema:Person
    232 sg:person.0637447533.36 schema:affiliation grid-institutes:grid.26999.3d
    233 schema:familyName Satou
    234 schema:givenName Shouichi
    235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637447533.36
    236 rdf:type schema:Person
    237 sg:person.0661346015.67 schema:affiliation grid-institutes:grid.26999.3d
    238 schema:familyName Kaneko
    239 schema:givenName Junichi
    240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661346015.67
    241 rdf:type schema:Person
    242 sg:person.0735351167.82 schema:affiliation grid-institutes:grid.26999.3d
    243 schema:familyName Kokudo
    244 schema:givenName Norihiro
    245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735351167.82
    246 rdf:type schema:Person
    247 sg:pub.10.1007/bf00635619 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003376544
    248 https://doi.org/10.1007/bf00635619
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1007/s00268-011-1320-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003923011
    251 https://doi.org/10.1007/s00268-011-1320-3
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1007/s00423-011-0837-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009255762
    254 https://doi.org/10.1007/s00423-011-0837-0
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1007/s00520-007-0384-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1035001534
    257 https://doi.org/10.1007/s00520-007-0384-y
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1007/s11136-004-4693-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1049790292
    260 https://doi.org/10.1007/s11136-004-4693-z
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1007/s11136-006-9133-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038681970
    263 https://doi.org/10.1007/s11136-006-9133-9
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1023/a:1015239020403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009117599
    266 https://doi.org/10.1023/a:1015239020403
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1186/1471-2261-11-24 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034355439
    269 https://doi.org/10.1186/1471-2261-11-24
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1186/1471-230x-10-78 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006659197
    272 https://doi.org/10.1186/1471-230x-10-78
    273 rdf:type schema:CreativeWork
    274 sg:pub.10.1186/1477-7525-4-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020545916
    275 https://doi.org/10.1186/1477-7525-4-5
    276 rdf:type schema:CreativeWork
    277 sg:pub.10.1245/s10434-012-2269-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037676641
    278 https://doi.org/10.1245/s10434-012-2269-7
    279 rdf:type schema:CreativeWork
    280 grid-institutes:grid.26999.3d schema:alternateName Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
    281 schema:name Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
    282 rdf:type schema:Organization
    283 grid-institutes:grid.414929.3 schema:alternateName Department of Hepato-Biliary-Pancreatic Surgery, Japanese Red Cross Medical Center, Tokyo, Japan
    284 schema:name Department of Hepato-Biliary-Pancreatic Surgery, Japanese Red Cross Medical Center, Tokyo, Japan
    285 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...