One-Stage Hepatectomy Following Portal Vein Embolization for Colorectal Liver Metastasis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-12-05

AUTHORS

Suguru Yamashita, Kiyoshi Hasegawa, Michiro Takahashi, Yosuke Inoue, Yoshihiro Sakamoto, Taku Aoki, Yasuhiko Sugawara, Norihiro Kokudo

ABSTRACT

BackgroundAlthough portal vein embolization (PVE) has been applied for surgical resection of colorectal liver metastases (CLM), the clinical usefulness of liver surgery following PVE for CLM remains unknown.MethodsA total of 115 patients were evaluated retrospectively. Among them, 49 underwent one-stage hepatectomy following PVE (PVE group). The remaining 66 patients underwent at least hemihepatectomy without PVE (non-PVE group). This analysis compared the short- and long-term outcomes between the PVE and non-PVE groups.ResultsThere were no deaths in either group. Using the Clavien–Dindo classification, the rates of postoperative morbidity ≥ grade 1 were 34.7 % in the PVE group and 25.0 % in the non-PVE group (p = 0.26). The 3-year overall survival rates were 54.6 and 64.5 % in the PVE and non-PVE groups, respectively (p = 0.89). The multivariate analysis the variable performance/nonperformance of PVE was not detected as an independent predictor of poor survival.ConclusionsOur one-stage hepatectomy policy of using PVE provides acceptable morbidity and favorable long-term outcomes. More... »

PAGES

622-628

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00268-012-1861-0

DOI

http://dx.doi.org/10.1007/s00268-012-1861-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009297647

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23212792


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