Effect of Ginkgo biloba Extract (EGb 761) on the Healing of Left Colonic Anastomoses in Rat View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-08

AUTHORS

Erol Kisli, Hülya Özdemir, Mustafa Kösem, Hatice Sürer, Ali Ciftçi, Mehmet Kanter

ABSTRACT

BACKGROUND: The aim of this study was to assess the effect of Ginkgo biloba extract (EGb 761) on healing of experimental colonic anastomoses in a rat model. METHODS: Rats were divided into four groups: postoperative day (POD) 3 untreated control group, POD 3 EGb 761 group, POD 7 untreated control group, and POD 7 EGb 761 group. In the oral EGb 761 groups, the agent was given at 9.6 mg daily per orogastric route using a 4-F fine feeding catheter. We measured bursting pressures and hydroxyproline content and histologically examined the resected anastomoses on POD 3 and POD 7. RESULTS: The bursting pressures increased more in the EGb 761 group than in the untreated control group on POD 3, but this difference was not statistically significant. Hydroxyproline content was higher in the EGb 761 group than in the untreated control group on POD 3, and this difference was statistically significant. Anastomosis bursting pressure values and hydroxyproline contents were significantly higher in the EGb 761 group than in the untreated control group on POD 7. Histological examination showed greater fibroblastic activity in the EGb 761 group than in the untreated control group on POD 3. There was no significant difference in anastomotic polimorphonuclear leukocyte, mononuclear cells and blood vessel neodevelopment between the POD 3 groups, but there was significant difference in fibroblastic activity and blood vessel neodevelopment between the POD 7 groups. CONCLUSIONS: These results showed us that EGb 761 administration resulted in enhanced stability of colonic anastomoses during the first postoperative week. More... »

PAGES

1652-1657

References to SciGraph publications

  • 2004-05. Positive effects of phenytoin on experimental colonic anastomoses in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2004-11. Effects of steroid on the healing of colonic anastomoses in the rat in TECHNIQUES IN COLOPROCTOLOGY
  • 1999-07. Stapled functional end-to-end anastomosis in Crohn’s disease in SURGERY TODAY
  • 2003-09. Neuroprotective effects of Ginkgo biloba extract in CELLULAR AND MOLECULAR LIFE SCIENCES
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00268-007-9049-8

    DOI

    http://dx.doi.org/10.1007/s00268-007-9049-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1001777740

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17578646


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Cardiorespiratory Medicine and Haematology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Administration, Oral", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Anastomosis, Surgical", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Colon", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hydrostatic Pressure", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hydroxyproline", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Models, Animal", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plant Extracts", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Rats", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Rats, Wistar", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Wound Healing", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Y\u00fcz\u00fcnc\u00fc Y\u0131l University", 
              "id": "https://www.grid.ac/institutes/grid.411703.0", 
              "name": [
                "Department of General Surgery, School of Medicine, Y\u00fcz\u00fcnc\u00fc Y\u0131l University, Van, Turkey"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kisli", 
            "givenName": "Erol", 
            "id": "sg:person.01073776321.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073776321.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Y\u00fcz\u00fcnc\u00fc Y\u0131l University", 
              "id": "https://www.grid.ac/institutes/grid.411703.0", 
              "name": [
                "Department of Pharmacology, School of Medicine, Y\u00fcz\u00fcnc\u00fc Y\u0131l University, Van, Turkey"
              ], 
              "type": "Organization"
            }, 
            "familyName": "\u00d6zdemir", 
            "givenName": "H\u00fclya", 
            "id": "sg:person.01210741225.46", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210741225.46"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Y\u00fcz\u00fcnc\u00fc Y\u0131l University", 
              "id": "https://www.grid.ac/institutes/grid.411703.0", 
              "name": [
                "Department of Pathology, School of Medicine, Y\u00fcz\u00fcnc\u00fc Y\u0131l University, Van, Turkey"
              ], 
              "type": "Organization"
            }, 
            "familyName": "K\u00f6sem", 
            "givenName": "Mustafa", 
            "id": "sg:person.0736321246.61", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736321246.61"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Ankara Atat\u00fcrk E\u011fitim ve Ara\u015ft\u0131rma Hastanesi", 
              "id": "https://www.grid.ac/institutes/grid.413783.a", 
              "name": [
                "Department of Biochemistry, Ankara Training and Research Hospital, Ankara, Turkey"
              ], 
              "type": "Organization"
            }, 
            "familyName": "S\u00fcrer", 
            "givenName": "Hatice", 
            "id": "sg:person.01262553034.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262553034.18"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Y\u00fcz\u00fcnc\u00fc Y\u0131l University", 
              "id": "https://www.grid.ac/institutes/grid.411703.0", 
              "name": [
                "Department of General Surgery, School of Medicine, Y\u00fcz\u00fcnc\u00fc Y\u0131l University, Van, Turkey"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cift\u00e7i", 
            "givenName": "Ali", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Trakya University", 
              "id": "https://www.grid.ac/institutes/grid.411693.8", 
              "name": [
                "Department of Histology and Embryology, School of Medicine, Trakya University, Edirne, Turkey"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kanter", 
            "givenName": "Mehmet", 
            "id": "sg:person.01112603164.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112603164.31"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/s0140-6736(05)79516-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004907700"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000211505", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005656345"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000179156", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008843506"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-0765.1988.tb01343.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010135699"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.286.2.208", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014629669"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00018-003-3080-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022177052", 
              "https://doi.org/10.1007/s00018-003-3080-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/00365528909093106", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022668742"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00384-003-0533-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024626550", 
              "https://doi.org/10.1007/s00384-003-0533-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0014-2999(90)94404-l", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024947560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0014-2999(90)94404-l", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024947560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/bjs.1800830108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035208195"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0002-9610(80)90302-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035248394"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf02483001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036371029", 
              "https://doi.org/10.1007/bf02483001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf02483001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036371029", 
              "https://doi.org/10.1007/bf02483001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0140-6736(92)93158-j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037520270"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0140-6736(92)93158-j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037520270"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000179208", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038726756"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/bjs.1800570208", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039967499"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/pmj.79.935.531", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040262909"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/pmj.79.935.531", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040262909"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/pmj.77.904.112", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042072024"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/pmj.77.904.112", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042072024"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0003-2697(81)90261-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043186512"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0021-9150(03)00015-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045659714"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-197305000-00002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047370550"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-197305000-00002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047370550"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0025-7753(02)73507-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049118062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10151-004-0150-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050990845", 
              "https://doi.org/10.1007/s10151-004-0150-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1432-2277.2002.tb00182.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053316732"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3748/wjg.v10.i4.560", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071362717"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074979777", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1075180174", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1075929865", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082639687", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2007-08", 
        "datePublishedReg": "2007-08-01", 
        "description": "BACKGROUND: The aim of this study was to assess the effect of Ginkgo biloba extract (EGb 761) on healing of experimental colonic anastomoses in a rat model.\nMETHODS: Rats were divided into four groups: postoperative day (POD) 3 untreated control group, POD 3 EGb 761 group, POD 7 untreated control group, and POD 7 EGb 761 group. In the oral EGb 761 groups, the agent was given at 9.6 mg daily per orogastric route using a 4-F fine feeding catheter. We measured bursting pressures and hydroxyproline content and histologically examined the resected anastomoses on POD 3 and POD 7.\nRESULTS: The bursting pressures increased more in the EGb 761 group than in the untreated control group on POD 3, but this difference was not statistically significant. Hydroxyproline content was higher in the EGb 761 group than in the untreated control group on POD 3, and this difference was statistically significant. Anastomosis bursting pressure values and hydroxyproline contents were significantly higher in the EGb 761 group than in the untreated control group on POD 7. Histological examination showed greater fibroblastic activity in the EGb 761 group than in the untreated control group on POD 3. There was no significant difference in anastomotic polimorphonuclear leukocyte, mononuclear cells and blood vessel neodevelopment between the POD 3 groups, but there was significant difference in fibroblastic activity and blood vessel neodevelopment between the POD 7 groups.\nCONCLUSIONS: These results showed us that EGb 761 administration resulted in enhanced stability of colonic anastomoses during the first postoperative week.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s00268-007-9049-8", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1086446", 
            "issn": [
              "0364-2313", 
              "1432-2323"
            ], 
            "name": "World Journal of Surgery", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "8", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "31"
          }
        ], 
        "name": "Effect of Ginkgo biloba Extract (EGb 761) on the Healing of Left Colonic Anastomoses in Rat", 
        "pagination": "1652-1657", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "08777d1fb37254aadeb6cdc9f5f8a0bfbe39e5555f578c0fc1bf554f56561501"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "17578646"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "7704052"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00268-007-9049-8"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1001777740"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00268-007-9049-8", 
          "https://app.dimensions.ai/details/publication/pub.1001777740"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T14:27", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13078_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007/s00268-007-9049-8"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00268-007-9049-8'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00268-007-9049-8'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00268-007-9049-8'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00268-007-9049-8'


     

    This table displays all metadata directly associated to this object as RDF triples.

    243 TRIPLES      21 PREDICATES      69 URIs      33 LITERALS      21 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00268-007-9049-8 schema:about N1040af1f434b414ebe3c8cfad7cc0d3a
    2 N300f5cf2ad12473d99f4ad17650d1523
    3 N3a879e3d840a40bd90c4cbe56d4b2cc4
    4 N4892f561104443f7849d5d674e0503d6
    5 N5075b26bca734abdbf40078c899ad1aa
    6 N522e60958aaf41539985542aafe0c0f2
    7 N67647cb00d804b0da6390dfbbec1a708
    8 N7d798f7900f74e43a22d357bcaf5abc1
    9 Nb2d4acca91af47b2b6db21a7b4a7a9b1
    10 Nda230514ffe74e4ba713b93622c4a0a1
    11 Nf2721ca1de1f434e86b6ad0aadb9f771
    12 Nfd0236178c2f426b858492cd52bc391c
    13 anzsrc-for:11
    14 anzsrc-for:1102
    15 schema:author N30b13967657e4274b9f2744fe33bbb24
    16 schema:citation sg:pub.10.1007/bf02483001
    17 sg:pub.10.1007/s00018-003-3080-1
    18 sg:pub.10.1007/s00384-003-0533-9
    19 sg:pub.10.1007/s10151-004-0150-9
    20 https://app.dimensions.ai/details/publication/pub.1074979777
    21 https://app.dimensions.ai/details/publication/pub.1075180174
    22 https://app.dimensions.ai/details/publication/pub.1075929865
    23 https://app.dimensions.ai/details/publication/pub.1082639687
    24 https://doi.org/10.1001/jama.286.2.208
    25 https://doi.org/10.1002/bjs.1800570208
    26 https://doi.org/10.1002/bjs.1800830108
    27 https://doi.org/10.1016/0002-9610(80)90302-5
    28 https://doi.org/10.1016/0003-2697(81)90261-x
    29 https://doi.org/10.1016/0014-2999(90)94404-l
    30 https://doi.org/10.1016/0140-6736(92)93158-j
    31 https://doi.org/10.1016/s0021-9150(03)00015-7
    32 https://doi.org/10.1016/s0025-7753(02)73507-0
    33 https://doi.org/10.1016/s0140-6736(05)79516-7
    34 https://doi.org/10.1097/00000658-197305000-00002
    35 https://doi.org/10.1111/j.1432-2277.2002.tb00182.x
    36 https://doi.org/10.1111/j.1600-0765.1988.tb01343.x
    37 https://doi.org/10.1136/pmj.77.904.112
    38 https://doi.org/10.1136/pmj.79.935.531
    39 https://doi.org/10.1159/000179156
    40 https://doi.org/10.1159/000179208
    41 https://doi.org/10.1159/000211505
    42 https://doi.org/10.3109/00365528909093106
    43 https://doi.org/10.3748/wjg.v10.i4.560
    44 schema:datePublished 2007-08
    45 schema:datePublishedReg 2007-08-01
    46 schema:description BACKGROUND: The aim of this study was to assess the effect of Ginkgo biloba extract (EGb 761) on healing of experimental colonic anastomoses in a rat model. METHODS: Rats were divided into four groups: postoperative day (POD) 3 untreated control group, POD 3 EGb 761 group, POD 7 untreated control group, and POD 7 EGb 761 group. In the oral EGb 761 groups, the agent was given at 9.6 mg daily per orogastric route using a 4-F fine feeding catheter. We measured bursting pressures and hydroxyproline content and histologically examined the resected anastomoses on POD 3 and POD 7. RESULTS: The bursting pressures increased more in the EGb 761 group than in the untreated control group on POD 3, but this difference was not statistically significant. Hydroxyproline content was higher in the EGb 761 group than in the untreated control group on POD 3, and this difference was statistically significant. Anastomosis bursting pressure values and hydroxyproline contents were significantly higher in the EGb 761 group than in the untreated control group on POD 7. Histological examination showed greater fibroblastic activity in the EGb 761 group than in the untreated control group on POD 3. There was no significant difference in anastomotic polimorphonuclear leukocyte, mononuclear cells and blood vessel neodevelopment between the POD 3 groups, but there was significant difference in fibroblastic activity and blood vessel neodevelopment between the POD 7 groups. CONCLUSIONS: These results showed us that EGb 761 administration resulted in enhanced stability of colonic anastomoses during the first postoperative week.
    47 schema:genre research_article
    48 schema:inLanguage en
    49 schema:isAccessibleForFree false
    50 schema:isPartOf Nde7d809489ba40af8200ac51520a9482
    51 Nef3e26fba1474b678dc77a6eb392f3fb
    52 sg:journal.1086446
    53 schema:name Effect of Ginkgo biloba Extract (EGb 761) on the Healing of Left Colonic Anastomoses in Rat
    54 schema:pagination 1652-1657
    55 schema:productId N14dd534817c94a768e430374324659ea
    56 N30c7ace6f38a4e61a4f945c1f141e004
    57 N393aec150e244e01be3e618f9baa0f4a
    58 N40457a7bfc694b5aacd627b822aee75e
    59 Na8032233b75245e5ae8941e83f576084
    60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001777740
    61 https://doi.org/10.1007/s00268-007-9049-8
    62 schema:sdDatePublished 2019-04-11T14:27
    63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    64 schema:sdPublisher Nf2cc5b5cc09147b6a553fab367f6b6e4
    65 schema:url http://link.springer.com/10.1007/s00268-007-9049-8
    66 sgo:license sg:explorer/license/
    67 sgo:sdDataset articles
    68 rdf:type schema:ScholarlyArticle
    69 N025a733bffaf49279d7b0ff0e1e8414b schema:affiliation https://www.grid.ac/institutes/grid.411703.0
    70 schema:familyName Ciftçi
    71 schema:givenName Ali
    72 rdf:type schema:Person
    73 N1040af1f434b414ebe3c8cfad7cc0d3a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    74 schema:name Models, Animal
    75 rdf:type schema:DefinedTerm
    76 N14dd534817c94a768e430374324659ea schema:name readcube_id
    77 schema:value 08777d1fb37254aadeb6cdc9f5f8a0bfbe39e5555f578c0fc1bf554f56561501
    78 rdf:type schema:PropertyValue
    79 N226add697fde45388f3a31b79243b92e rdf:first sg:person.0736321246.61
    80 rdf:rest Nd9e7a8a7c0a74335a714f2c69afdc569
    81 N2d188a68b13e4d78a91e15bf6a0e237f rdf:first sg:person.01112603164.31
    82 rdf:rest rdf:nil
    83 N300f5cf2ad12473d99f4ad17650d1523 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    84 schema:name Plant Extracts
    85 rdf:type schema:DefinedTerm
    86 N30b13967657e4274b9f2744fe33bbb24 rdf:first sg:person.01073776321.56
    87 rdf:rest Na6f2b387b40346a3a4568370896d7369
    88 N30c7ace6f38a4e61a4f945c1f141e004 schema:name pubmed_id
    89 schema:value 17578646
    90 rdf:type schema:PropertyValue
    91 N393aec150e244e01be3e618f9baa0f4a schema:name doi
    92 schema:value 10.1007/s00268-007-9049-8
    93 rdf:type schema:PropertyValue
    94 N3a879e3d840a40bd90c4cbe56d4b2cc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    95 schema:name Hydrostatic Pressure
    96 rdf:type schema:DefinedTerm
    97 N40457a7bfc694b5aacd627b822aee75e schema:name nlm_unique_id
    98 schema:value 7704052
    99 rdf:type schema:PropertyValue
    100 N4892f561104443f7849d5d674e0503d6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    101 schema:name Male
    102 rdf:type schema:DefinedTerm
    103 N5075b26bca734abdbf40078c899ad1aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    104 schema:name Administration, Oral
    105 rdf:type schema:DefinedTerm
    106 N522e60958aaf41539985542aafe0c0f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    107 schema:name Rats, Wistar
    108 rdf:type schema:DefinedTerm
    109 N67647cb00d804b0da6390dfbbec1a708 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    110 schema:name Animals
    111 rdf:type schema:DefinedTerm
    112 N7d798f7900f74e43a22d357bcaf5abc1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    113 schema:name Hydroxyproline
    114 rdf:type schema:DefinedTerm
    115 Na6f2b387b40346a3a4568370896d7369 rdf:first sg:person.01210741225.46
    116 rdf:rest N226add697fde45388f3a31b79243b92e
    117 Na8032233b75245e5ae8941e83f576084 schema:name dimensions_id
    118 schema:value pub.1001777740
    119 rdf:type schema:PropertyValue
    120 Nb2d4acca91af47b2b6db21a7b4a7a9b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Anastomosis, Surgical
    122 rdf:type schema:DefinedTerm
    123 Nbf8b31f7500c40b5a0ae7ae44bb0d5ae rdf:first N025a733bffaf49279d7b0ff0e1e8414b
    124 rdf:rest N2d188a68b13e4d78a91e15bf6a0e237f
    125 Nd9e7a8a7c0a74335a714f2c69afdc569 rdf:first sg:person.01262553034.18
    126 rdf:rest Nbf8b31f7500c40b5a0ae7ae44bb0d5ae
    127 Nda230514ffe74e4ba713b93622c4a0a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Rats
    129 rdf:type schema:DefinedTerm
    130 Nde7d809489ba40af8200ac51520a9482 schema:volumeNumber 31
    131 rdf:type schema:PublicationVolume
    132 Nef3e26fba1474b678dc77a6eb392f3fb schema:issueNumber 8
    133 rdf:type schema:PublicationIssue
    134 Nf2721ca1de1f434e86b6ad0aadb9f771 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    135 schema:name Wound Healing
    136 rdf:type schema:DefinedTerm
    137 Nf2cc5b5cc09147b6a553fab367f6b6e4 schema:name Springer Nature - SN SciGraph project
    138 rdf:type schema:Organization
    139 Nfd0236178c2f426b858492cd52bc391c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    140 schema:name Colon
    141 rdf:type schema:DefinedTerm
    142 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    143 schema:name Medical and Health Sciences
    144 rdf:type schema:DefinedTerm
    145 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
    146 schema:name Cardiorespiratory Medicine and Haematology
    147 rdf:type schema:DefinedTerm
    148 sg:journal.1086446 schema:issn 0364-2313
    149 1432-2323
    150 schema:name World Journal of Surgery
    151 rdf:type schema:Periodical
    152 sg:person.01073776321.56 schema:affiliation https://www.grid.ac/institutes/grid.411703.0
    153 schema:familyName Kisli
    154 schema:givenName Erol
    155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073776321.56
    156 rdf:type schema:Person
    157 sg:person.01112603164.31 schema:affiliation https://www.grid.ac/institutes/grid.411693.8
    158 schema:familyName Kanter
    159 schema:givenName Mehmet
    160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112603164.31
    161 rdf:type schema:Person
    162 sg:person.01210741225.46 schema:affiliation https://www.grid.ac/institutes/grid.411703.0
    163 schema:familyName Özdemir
    164 schema:givenName Hülya
    165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210741225.46
    166 rdf:type schema:Person
    167 sg:person.01262553034.18 schema:affiliation https://www.grid.ac/institutes/grid.413783.a
    168 schema:familyName Sürer
    169 schema:givenName Hatice
    170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262553034.18
    171 rdf:type schema:Person
    172 sg:person.0736321246.61 schema:affiliation https://www.grid.ac/institutes/grid.411703.0
    173 schema:familyName Kösem
    174 schema:givenName Mustafa
    175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736321246.61
    176 rdf:type schema:Person
    177 sg:pub.10.1007/bf02483001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036371029
    178 https://doi.org/10.1007/bf02483001
    179 rdf:type schema:CreativeWork
    180 sg:pub.10.1007/s00018-003-3080-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022177052
    181 https://doi.org/10.1007/s00018-003-3080-1
    182 rdf:type schema:CreativeWork
    183 sg:pub.10.1007/s00384-003-0533-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024626550
    184 https://doi.org/10.1007/s00384-003-0533-9
    185 rdf:type schema:CreativeWork
    186 sg:pub.10.1007/s10151-004-0150-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050990845
    187 https://doi.org/10.1007/s10151-004-0150-9
    188 rdf:type schema:CreativeWork
    189 https://app.dimensions.ai/details/publication/pub.1074979777 schema:CreativeWork
    190 https://app.dimensions.ai/details/publication/pub.1075180174 schema:CreativeWork
    191 https://app.dimensions.ai/details/publication/pub.1075929865 schema:CreativeWork
    192 https://app.dimensions.ai/details/publication/pub.1082639687 schema:CreativeWork
    193 https://doi.org/10.1001/jama.286.2.208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014629669
    194 rdf:type schema:CreativeWork
    195 https://doi.org/10.1002/bjs.1800570208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039967499
    196 rdf:type schema:CreativeWork
    197 https://doi.org/10.1002/bjs.1800830108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035208195
    198 rdf:type schema:CreativeWork
    199 https://doi.org/10.1016/0002-9610(80)90302-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035248394
    200 rdf:type schema:CreativeWork
    201 https://doi.org/10.1016/0003-2697(81)90261-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043186512
    202 rdf:type schema:CreativeWork
    203 https://doi.org/10.1016/0014-2999(90)94404-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1024947560
    204 rdf:type schema:CreativeWork
    205 https://doi.org/10.1016/0140-6736(92)93158-j schema:sameAs https://app.dimensions.ai/details/publication/pub.1037520270
    206 rdf:type schema:CreativeWork
    207 https://doi.org/10.1016/s0021-9150(03)00015-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045659714
    208 rdf:type schema:CreativeWork
    209 https://doi.org/10.1016/s0025-7753(02)73507-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049118062
    210 rdf:type schema:CreativeWork
    211 https://doi.org/10.1016/s0140-6736(05)79516-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004907700
    212 rdf:type schema:CreativeWork
    213 https://doi.org/10.1097/00000658-197305000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047370550
    214 rdf:type schema:CreativeWork
    215 https://doi.org/10.1111/j.1432-2277.2002.tb00182.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053316732
    216 rdf:type schema:CreativeWork
    217 https://doi.org/10.1111/j.1600-0765.1988.tb01343.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010135699
    218 rdf:type schema:CreativeWork
    219 https://doi.org/10.1136/pmj.77.904.112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042072024
    220 rdf:type schema:CreativeWork
    221 https://doi.org/10.1136/pmj.79.935.531 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040262909
    222 rdf:type schema:CreativeWork
    223 https://doi.org/10.1159/000179156 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008843506
    224 rdf:type schema:CreativeWork
    225 https://doi.org/10.1159/000179208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038726756
    226 rdf:type schema:CreativeWork
    227 https://doi.org/10.1159/000211505 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005656345
    228 rdf:type schema:CreativeWork
    229 https://doi.org/10.3109/00365528909093106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022668742
    230 rdf:type schema:CreativeWork
    231 https://doi.org/10.3748/wjg.v10.i4.560 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071362717
    232 rdf:type schema:CreativeWork
    233 https://www.grid.ac/institutes/grid.411693.8 schema:alternateName Trakya University
    234 schema:name Department of Histology and Embryology, School of Medicine, Trakya University, Edirne, Turkey
    235 rdf:type schema:Organization
    236 https://www.grid.ac/institutes/grid.411703.0 schema:alternateName Yüzüncü Yıl University
    237 schema:name Department of General Surgery, School of Medicine, Yüzüncü Yıl University, Van, Turkey
    238 Department of Pathology, School of Medicine, Yüzüncü Yıl University, Van, Turkey
    239 Department of Pharmacology, School of Medicine, Yüzüncü Yıl University, Van, Turkey
    240 rdf:type schema:Organization
    241 https://www.grid.ac/institutes/grid.413783.a schema:alternateName Ankara Atatürk Eğitim ve Araştırma Hastanesi
    242 schema:name Department of Biochemistry, Ankara Training and Research Hospital, Ankara, Turkey
    243 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...