Can Sporadic Medullary Thyroid Carcinoma Be Biochemically Predicted? Prospective Analysis of 66 Operated Patients with Elevated Serum Calcitonin Levels View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-08

AUTHORS

Maurizio Iacobone, Patricia Niccoli-Sire, Frederic Sebag, Catherine De Micco, Jean-François Henry

ABSTRACT

Measuring serum calcitonin (CT) in patients with thyroid diseases allows preoperative diagnoses of sporadic medullary thyroid carcinoma (MTC) and C-cell hyperplasia (CCH). The aim of this prospective study was to distinguish biochemically between CCH and MTC. Basal CT (bCT) was determined in 7276 consecutive patients referred for thyroid disease. Patients with recurrent, persistent, or familial MTC were excluded. When bCT was > 10 pg/ml a pentagastrin-stimulated CT (sCT) assay was performed. Patients were routinely operated on when bCT > 30 pg/ml or sCT > 100 pg/ml or when other indications for surgery were present. An extensive search for CCH or microscopic MTC was conducted by immunochemistry. Pathologic findings were correlated with the bCT and sCT values. In this study 66 patients were included. No morphologic alterations of C-cells were observed in 5 patients; 16 patients presented with CCH and 45 with MTC. Statistical analysis revealed a correlation of sCT and overall bCT with tumor size and staging (p <0.001). Considering cutoff values for bCT of < or = 30 pg/ml and for sCT of < or = 200 pg/ml, the positive predictive value of the test to detect MTC was 100% and the negative predictive value 63%. No patients with MTC at stage 2 to 4 had bCT <30 pg/ml or sCT <200 pg/ml. A bCT value of < or = 30 pg/ml or sCT < or = 200 pg/ml (or both) is highly predictive of MTC, requiring total thyroidectomy with lymph node dissection. Values of bCT <30 pg/ml and sCT <200 pg/ml do not distinguish between CCH and MTC at stage 1. In this case total thyroidectomy at least is recommended, and the role of nodal dissection might be discussed. More... »

PAGES

886-890

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00268-002-6613-0

DOI

http://dx.doi.org/10.1007/s00268-002-6613-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044926354

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12016469


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcitonin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma, Medullary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diagnosis, Differential", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hyperplasia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pentagastrin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sensitivity and Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thyroid Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thyroid Gland", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thyroid Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Timone", 
          "id": "https://www.grid.ac/institutes/grid.411266.6", 
          "name": [
            "Department of General and Endocrine Surgery, University Hospital La Timone, 264 Rue Saint Pierre, 13385\nMarseilles, France, FRANCE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iacobone", 
        "givenName": "Maurizio", 
        "id": "sg:person.0652565205.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0652565205.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Timone", 
          "id": "https://www.grid.ac/institutes/grid.411266.6", 
          "name": [
            "Department of General and Endocrine Surgery, University Hospital La Timone, 264 Rue Saint Pierre, 13385\nMarseilles, France, FRANCE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Niccoli-Sire", 
        "givenName": "Patricia", 
        "id": "sg:person.0674131701.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674131701.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Timone", 
          "id": "https://www.grid.ac/institutes/grid.411266.6", 
          "name": [
            "Department of General and Endocrine Surgery, University Hospital La Timone, 264 Rue Saint Pierre, 13385\nMarseilles, France, FRANCE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sebag", 
        "givenName": "Frederic", 
        "id": "sg:person.01122766065.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01122766065.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Timone", 
          "id": "https://www.grid.ac/institutes/grid.411266.6", 
          "name": [
            "Department of General and Endocrine Surgery, University Hospital La Timone, 264 Rue Saint Pierre, 13385\nMarseilles, France, FRANCE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "De Micco", 
        "givenName": "Catherine", 
        "id": "sg:person.01161003130.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161003130.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Timone", 
          "id": "https://www.grid.ac/institutes/grid.411266.6", 
          "name": [
            "Department of General and Endocrine Surgery, University Hospital La Timone, 264 Rue Saint Pierre, 13385\nMarseilles, France, FRANCE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Henry", 
        "givenName": "Jean-Fran\u00e7ois", 
        "id": "sg:person.01372573656.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372573656.27"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2002-08", 
    "datePublishedReg": "2002-08-01", 
    "description": "Measuring serum calcitonin (CT) in patients with thyroid diseases allows preoperative diagnoses of sporadic medullary thyroid carcinoma (MTC) and C-cell hyperplasia (CCH). The aim of this prospective study was to distinguish biochemically between CCH and MTC. Basal CT (bCT) was determined in 7276 consecutive patients referred for thyroid disease. Patients with recurrent, persistent, or familial MTC were excluded. When bCT was > 10 pg/ml a pentagastrin-stimulated CT (sCT) assay was performed. Patients were routinely operated on when bCT > 30 pg/ml or sCT > 100 pg/ml or when other indications for surgery were present. An extensive search for CCH or microscopic MTC was conducted by immunochemistry. Pathologic findings were correlated with the bCT and sCT values. In this study 66 patients were included. No morphologic alterations of C-cells were observed in 5 patients; 16 patients presented with CCH and 45 with MTC. Statistical analysis revealed a correlation of sCT and overall bCT with tumor size and staging (p <0.001). Considering cutoff values for bCT of < or = 30 pg/ml and for sCT of < or = 200 pg/ml, the positive predictive value of the test to detect MTC was 100% and the negative predictive value 63%. No patients with MTC at stage 2 to 4 had bCT <30 pg/ml or sCT <200 pg/ml. A bCT value of < or = 30 pg/ml or sCT < or = 200 pg/ml (or both) is highly predictive of MTC, requiring total thyroidectomy with lymph node dissection. Values of bCT <30 pg/ml and sCT <200 pg/ml do not distinguish between CCH and MTC at stage 1. In this case total thyroidectomy at least is recommended, and the role of nodal dissection might be discussed.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00268-002-6613-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1086446", 
        "issn": [
          "0364-2313", 
          "1432-2323"
        ], 
        "name": "World Journal of Surgery", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "name": "Can Sporadic Medullary Thyroid Carcinoma Be Biochemically Predicted? Prospective Analysis of 66 Operated Patients with Elevated Serum Calcitonin Levels", 
    "pagination": "886-890", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d5ff79d22ae7c09788dde04b521dbff20980e422b9e47562751ed838419cafd7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12016469"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7704052"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00268-002-6613-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1044926354"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00268-002-6613-0", 
      "https://app.dimensions.ai/details/publication/pub.1044926354"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:09", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000515.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00268-002-6613-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00268-002-6613-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00268-002-6613-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00268-002-6613-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00268-002-6613-0'


 

This table displays all metadata directly associated to this object as RDF triples.

173 TRIPLES      20 PREDICATES      48 URIs      40 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00268-002-6613-0 schema:about N0209802a154c487b87d3b5e12a30270a
2 N0dab14b29df34da4ba74784e93de7cec
3 N2633a813b14e4733b7da0597d692abd6
4 N3375869c4ebc492b93649ca9b226b922
5 N346b0e79cd4949e4a777346b1fc2ae7c
6 N34d23ce943dc443f832a85cf05b21a1a
7 N3d4e761cd7134d6e882b45b9a120024e
8 N4e4eae5390c14e47bc5ffa10b00157bf
9 N64271b46a5054b7291d7f087a6142989
10 N643ad4d644724c81b5c0411d54850d02
11 N9404066ea17c408782234561c38784b6
12 N96d64a3d06b646c98af82edfab6bdf45
13 N9a02404ffec44ec79c68697bd224b366
14 Nb69e20ca35204e7cb9953b2978780b6a
15 Nc1b3f796a5684da2b72f4696a809b8f8
16 Ncc9d0227d4e9457e932a0125bdf90b10
17 Ndfabf8f2c6814448909a25051c88ad1a
18 Ne6f29b10b4de47869ef909fb159dfda3
19 Nedd9c21462a64149a7708631de72d31e
20 anzsrc-for:11
21 anzsrc-for:1103
22 schema:author N551125f11fd34dd194be4c41745cec8e
23 schema:datePublished 2002-08
24 schema:datePublishedReg 2002-08-01
25 schema:description Measuring serum calcitonin (CT) in patients with thyroid diseases allows preoperative diagnoses of sporadic medullary thyroid carcinoma (MTC) and C-cell hyperplasia (CCH). The aim of this prospective study was to distinguish biochemically between CCH and MTC. Basal CT (bCT) was determined in 7276 consecutive patients referred for thyroid disease. Patients with recurrent, persistent, or familial MTC were excluded. When bCT was > 10 pg/ml a pentagastrin-stimulated CT (sCT) assay was performed. Patients were routinely operated on when bCT > 30 pg/ml or sCT > 100 pg/ml or when other indications for surgery were present. An extensive search for CCH or microscopic MTC was conducted by immunochemistry. Pathologic findings were correlated with the bCT and sCT values. In this study 66 patients were included. No morphologic alterations of C-cells were observed in 5 patients; 16 patients presented with CCH and 45 with MTC. Statistical analysis revealed a correlation of sCT and overall bCT with tumor size and staging (p <0.001). Considering cutoff values for bCT of < or = 30 pg/ml and for sCT of < or = 200 pg/ml, the positive predictive value of the test to detect MTC was 100% and the negative predictive value 63%. No patients with MTC at stage 2 to 4 had bCT <30 pg/ml or sCT <200 pg/ml. A bCT value of < or = 30 pg/ml or sCT < or = 200 pg/ml (or both) is highly predictive of MTC, requiring total thyroidectomy with lymph node dissection. Values of bCT <30 pg/ml and sCT <200 pg/ml do not distinguish between CCH and MTC at stage 1. In this case total thyroidectomy at least is recommended, and the role of nodal dissection might be discussed.
26 schema:genre research_article
27 schema:inLanguage en
28 schema:isAccessibleForFree false
29 schema:isPartOf Nd0622b0fe12a404cbc8417e665112ebf
30 Ndfcfbb5a1cef47df864562b5ba4e1554
31 sg:journal.1086446
32 schema:name Can Sporadic Medullary Thyroid Carcinoma Be Biochemically Predicted? Prospective Analysis of 66 Operated Patients with Elevated Serum Calcitonin Levels
33 schema:pagination 886-890
34 schema:productId N3e5fd6f652ce4417855068dcb0cdbb2f
35 Nabb11ef791ec4fb38b510b85e5f43aa8
36 Ncbc5c0eedc53498e9c79b023cac38972
37 Nde8041f114f14a51a6143cee75a914f6
38 Nf2a34655651b4a3295843f5194a66c42
39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044926354
40 https://doi.org/10.1007/s00268-002-6613-0
41 schema:sdDatePublished 2019-04-10T19:09
42 schema:sdLicense https://scigraph.springernature.com/explorer/license/
43 schema:sdPublisher N27925bc43966444bb67490c5505b18fa
44 schema:url http://link.springer.com/10.1007%2Fs00268-002-6613-0
45 sgo:license sg:explorer/license/
46 sgo:sdDataset articles
47 rdf:type schema:ScholarlyArticle
48 N0209802a154c487b87d3b5e12a30270a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
49 schema:name Thyroid Gland
50 rdf:type schema:DefinedTerm
51 N0dab14b29df34da4ba74784e93de7cec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
52 schema:name Middle Aged
53 rdf:type schema:DefinedTerm
54 N2633a813b14e4733b7da0597d692abd6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
55 schema:name Pentagastrin
56 rdf:type schema:DefinedTerm
57 N27925bc43966444bb67490c5505b18fa schema:name Springer Nature - SN SciGraph project
58 rdf:type schema:Organization
59 N321b4ada5f074a2290c6f63b71a0e829 rdf:first sg:person.01161003130.33
60 rdf:rest N63b20a8f755d40d39ffd06dabdfb2ba6
61 N3375869c4ebc492b93649ca9b226b922 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
62 schema:name Biomarkers, Tumor
63 rdf:type schema:DefinedTerm
64 N346b0e79cd4949e4a777346b1fc2ae7c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
65 schema:name Male
66 rdf:type schema:DefinedTerm
67 N34d23ce943dc443f832a85cf05b21a1a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Diagnosis, Differential
69 rdf:type schema:DefinedTerm
70 N3d4e761cd7134d6e882b45b9a120024e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Carcinoma, Medullary
72 rdf:type schema:DefinedTerm
73 N3e5fd6f652ce4417855068dcb0cdbb2f schema:name doi
74 schema:value 10.1007/s00268-002-6613-0
75 rdf:type schema:PropertyValue
76 N4e4eae5390c14e47bc5ffa10b00157bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Aged, 80 and over
78 rdf:type schema:DefinedTerm
79 N551125f11fd34dd194be4c41745cec8e rdf:first sg:person.0652565205.09
80 rdf:rest Nf6d51f8a2ef64f26a4c268e5052a464b
81 N63b20a8f755d40d39ffd06dabdfb2ba6 rdf:first sg:person.01372573656.27
82 rdf:rest rdf:nil
83 N64271b46a5054b7291d7f087a6142989 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Female
85 rdf:type schema:DefinedTerm
86 N643ad4d644724c81b5c0411d54850d02 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Hyperplasia
88 rdf:type schema:DefinedTerm
89 N9404066ea17c408782234561c38784b6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Adolescent
91 rdf:type schema:DefinedTerm
92 N96d64a3d06b646c98af82edfab6bdf45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Sensitivity and Specificity
94 rdf:type schema:DefinedTerm
95 N9a02404ffec44ec79c68697bd224b366 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Aged
97 rdf:type schema:DefinedTerm
98 Nabb11ef791ec4fb38b510b85e5f43aa8 schema:name readcube_id
99 schema:value d5ff79d22ae7c09788dde04b521dbff20980e422b9e47562751ed838419cafd7
100 rdf:type schema:PropertyValue
101 Nb69e20ca35204e7cb9953b2978780b6a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Humans
103 rdf:type schema:DefinedTerm
104 Nc1b3f796a5684da2b72f4696a809b8f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Adult
106 rdf:type schema:DefinedTerm
107 Ncbc5c0eedc53498e9c79b023cac38972 schema:name pubmed_id
108 schema:value 12016469
109 rdf:type schema:PropertyValue
110 Ncc9d0227d4e9457e932a0125bdf90b10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Thyroid Diseases
112 rdf:type schema:DefinedTerm
113 Nd0622b0fe12a404cbc8417e665112ebf schema:volumeNumber 26
114 rdf:type schema:PublicationVolume
115 Nde8041f114f14a51a6143cee75a914f6 schema:name dimensions_id
116 schema:value pub.1044926354
117 rdf:type schema:PropertyValue
118 Ndfabf8f2c6814448909a25051c88ad1a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Prospective Studies
120 rdf:type schema:DefinedTerm
121 Ndfcfbb5a1cef47df864562b5ba4e1554 schema:issueNumber 8
122 rdf:type schema:PublicationIssue
123 Ne31b76e86b4f4953958faf93a19c7632 rdf:first sg:person.01122766065.22
124 rdf:rest N321b4ada5f074a2290c6f63b71a0e829
125 Ne6f29b10b4de47869ef909fb159dfda3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Calcitonin
127 rdf:type schema:DefinedTerm
128 Nedd9c21462a64149a7708631de72d31e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Thyroid Neoplasms
130 rdf:type schema:DefinedTerm
131 Nf2a34655651b4a3295843f5194a66c42 schema:name nlm_unique_id
132 schema:value 7704052
133 rdf:type schema:PropertyValue
134 Nf6d51f8a2ef64f26a4c268e5052a464b rdf:first sg:person.0674131701.39
135 rdf:rest Ne31b76e86b4f4953958faf93a19c7632
136 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
137 schema:name Medical and Health Sciences
138 rdf:type schema:DefinedTerm
139 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
140 schema:name Clinical Sciences
141 rdf:type schema:DefinedTerm
142 sg:journal.1086446 schema:issn 0364-2313
143 1432-2323
144 schema:name World Journal of Surgery
145 rdf:type schema:Periodical
146 sg:person.01122766065.22 schema:affiliation https://www.grid.ac/institutes/grid.411266.6
147 schema:familyName Sebag
148 schema:givenName Frederic
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01122766065.22
150 rdf:type schema:Person
151 sg:person.01161003130.33 schema:affiliation https://www.grid.ac/institutes/grid.411266.6
152 schema:familyName De Micco
153 schema:givenName Catherine
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161003130.33
155 rdf:type schema:Person
156 sg:person.01372573656.27 schema:affiliation https://www.grid.ac/institutes/grid.411266.6
157 schema:familyName Henry
158 schema:givenName Jean-François
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372573656.27
160 rdf:type schema:Person
161 sg:person.0652565205.09 schema:affiliation https://www.grid.ac/institutes/grid.411266.6
162 schema:familyName Iacobone
163 schema:givenName Maurizio
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0652565205.09
165 rdf:type schema:Person
166 sg:person.0674131701.39 schema:affiliation https://www.grid.ac/institutes/grid.411266.6
167 schema:familyName Niccoli-Sire
168 schema:givenName Patricia
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674131701.39
170 rdf:type schema:Person
171 https://www.grid.ac/institutes/grid.411266.6 schema:alternateName Hôpital de la Timone
172 schema:name Department of General and Endocrine Surgery, University Hospital La Timone, 264 Rue Saint Pierre, 13385 Marseilles, France, FRANCE
173 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...