Clinicopathological prognostic factors and impact of surgical treatment of mass-forming intrahepatic cholangiocarcinoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-06

AUTHORS

Shohachi Suzuki, Takanori Sakaguchi, Yoshihiro Yokoi, Kazuya Okamoto, Kiyotaka Kurachi, Yasuo Tsuchiya, Takuya Okumura, Hiroyuki Konno, Satoshi Baba, Satoshi Nakamura

ABSTRACT

The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Two or more segmentectomies of the liver with systematic lymphadenectomy were performed in 18 patients. Resection of the extrahepatic bile duct was performed in 14 patients, and reconstruction of the portal vein was accomplished in 5 patients. Stage IVA or IVB tumors were seen in 13 patients, and lymph node (LN) metastasis was present in 14 patients. The estimated 5-year survival rate after surgery for mass-forming ICC was 28%, with median survival time of 18 months. In univariate analysis, five variables were determined to be significantly correlated with poor survival of patients with mass-forming ICC after surgery. These variables include mass-forming ICC with periductal infiltration, perineural invasion, portal vein invasion, presence of intrahepatic metastasis, and two or more LN metastases. Survival rates of 5 patients without LN metastasis and 6 patients with a single LN metastasis were 80% and 33% at 5 years, respectively, while 8 patients with two or more LN metastasis failed to survive beyond 2 years. Multivariate analysis revealed the presence of intrahepatic metastasis to be an independent prognostic factor of poor survival. Hepatectomy with resection of the extrahepatic bile duct and systematic lymphadenectomy yields a good chance for prolonged survival for patients with mass-forming ICC when the lesion is singular and LN metastasis is limited to a regional LN. Because the presence of intrahepatic metastasis was closely related to a poor prognosis in patients with mass-forming ICC, efficacious chemotherapy would be needed to control development of the lesion. More... »

PAGES

687-693

References to SciGraph publications

  • 1999-07. Clinicopathological features and outcome of hepatic resection for intrahepatic cholangiocarcinoma in Japan in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 1995-01. Surgical treatment of cholangiocellular carcinoma in WORLD JOURNAL OF SURGERY
  • 1998-04. Surgical management of intrahepatic cholangiocarcinoma: A 31-year experience in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 1999-07. Intrahepatic cholangiocarcinoma in Korea in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 1999-07. Resection of intrahepatic cholangiocarcinoma: a Western experience in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00268-001-0291-1

    DOI

    http://dx.doi.org/10.1007/s00268-001-0291-1

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1004801848

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12053220


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cholangiocarcinoma", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hepatectomy", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Liver Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Neoplasm Invasiveness", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Neoplasm Recurrence, Local", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prognosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Retrospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Survival Analysis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Survivors", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Suzuki", 
            "givenName": "Shohachi", 
            "id": "sg:person.016543515244.33", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016543515244.33"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sakaguchi", 
            "givenName": "Takanori", 
            "id": "sg:person.0733465475.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733465475.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yokoi", 
            "givenName": "Yoshihiro", 
            "id": "sg:person.01226740305.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226740305.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Okamoto", 
            "givenName": "Kazuya", 
            "id": "sg:person.01132117403.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132117403.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kurachi", 
            "givenName": "Kiyotaka", 
            "id": "sg:person.01356133636.70", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356133636.70"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tsuchiya", 
            "givenName": "Yasuo", 
            "id": "sg:person.01136236303.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136236303.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Okumura", 
            "givenName": "Takuya", 
            "id": "sg:person.01252464703.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252464703.38"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Konno", 
            "givenName": "Hiroyuki", 
            "id": "sg:person.0730101772.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730101772.16"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Pathology II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Baba", 
            "givenName": "Satoshi", 
            "id": "sg:person.015605373132.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015605373132.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hamamatsu University", 
              "id": "https://www.grid.ac/institutes/grid.411951.9", 
              "name": [
                "Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nakamura", 
            "givenName": "Satoshi", 
            "id": "sg:person.015555041242.12", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015555041242.12"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1002/1097-0142(19891201)64:11<2226::aid-cncr2820641107>3.0.co;2-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003826236"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(197701)39:1<232::aid-cncr2820390137>3.0.co;2-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007431890"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1440-1746.1994.tb01271.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011117396"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0046-8177(88)80156-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014348394"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s005340050092", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014759806", 
              "https://doi.org/10.1007/s005340050092"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1365-2168.1998.00815.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017420888"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/bjs.1800831108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017704377"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s005340050097", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018557923", 
              "https://doi.org/10.1007/s005340050097"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-0142(19981101)83:9<1923::aid-cncr7>3.0.co;2-#", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024123175"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archsurg.1995.01430100051011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026507049"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s005340050094", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026704955", 
              "https://doi.org/10.1007/s005340050094"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-199204000-00007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028029505"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-199204000-00007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028029505"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0748-7983(96)90853-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030817398"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(19951215)76:12<2449::aid-cncr2820761208>3.0.co;2-v", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035044975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00316984", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037973793", 
              "https://doi.org/10.1007/bf00316984"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00316984", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037973793", 
              "https://doi.org/10.1007/bf00316984"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/1992/93976", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040346068"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/pl00009949", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043509058", 
              "https://doi.org/10.1007/pl00009949"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jso.2930590111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051295820"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-199610000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060134367"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-199801000-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060134679"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-199801000-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060134679"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-199801000-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060134679"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000658-199801000-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060134679"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1075519418", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078393934", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078400637", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2002-06", 
        "datePublishedReg": "2002-06-01", 
        "description": "The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Two or more segmentectomies of the liver with systematic lymphadenectomy were performed in 18 patients. Resection of the extrahepatic bile duct was performed in 14 patients, and reconstruction of the portal vein was accomplished in 5 patients. Stage IVA or IVB tumors were seen in 13 patients, and lymph node (LN) metastasis was present in 14 patients. The estimated 5-year survival rate after surgery for mass-forming ICC was 28%, with median survival time of 18 months. In univariate analysis, five variables were determined to be significantly correlated with poor survival of patients with mass-forming ICC after surgery. These variables include mass-forming ICC with periductal infiltration, perineural invasion, portal vein invasion, presence of intrahepatic metastasis, and two or more LN metastases. Survival rates of 5 patients without LN metastasis and 6 patients with a single LN metastasis were 80% and 33% at 5 years, respectively, while 8 patients with two or more LN metastasis failed to survive beyond 2 years. Multivariate analysis revealed the presence of intrahepatic metastasis to be an independent prognostic factor of poor survival. Hepatectomy with resection of the extrahepatic bile duct and systematic lymphadenectomy yields a good chance for prolonged survival for patients with mass-forming ICC when the lesion is singular and LN metastasis is limited to a regional LN. Because the presence of intrahepatic metastasis was closely related to a poor prognosis in patients with mass-forming ICC, efficacious chemotherapy would be needed to control development of the lesion.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s00268-001-0291-1", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1086446", 
            "issn": [
              "0364-2313", 
              "1432-2323"
            ], 
            "name": "World Journal of Surgery", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "6", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "26"
          }
        ], 
        "name": "Clinicopathological prognostic factors and impact of surgical treatment of mass-forming intrahepatic cholangiocarcinoma", 
        "pagination": "687-693", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "16e15ca0558e978707b66d40089b3c88c22d95de06532fcf76418b7f35230fa7"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "12053220"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "7704052"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00268-001-0291-1"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1004801848"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00268-001-0291-1", 
          "https://app.dimensions.ai/details/publication/pub.1004801848"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T14:33", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13106_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007%2Fs00268-001-0291-1"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00268-001-0291-1'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00268-001-0291-1'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00268-001-0291-1'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00268-001-0291-1'


     

    This table displays all metadata directly associated to this object as RDF triples.

    264 TRIPLES      21 PREDICATES      67 URIs      36 LITERALS      24 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00268-001-0291-1 schema:about N01d6d5c509b94e9b9697c6c15f636f68
    2 N02dd8b457558437c8c5440035491a531
    3 N191f998a579f4a53b1d3c3f3198d18cf
    4 N30870949f14845008942bf288d32f07c
    5 N42641aee0d1045a593f8f343899bcec1
    6 N53c3771acec549008f932823cab16959
    7 N57a818b0c3e5441eb736848af7d3a3a8
    8 N5cc003eaa77e43d7b78ac24821f558e1
    9 N6a7299b8005b4c56805488668e68fe1c
    10 N6f46cbf7d8784c1d9b37c9e482b4b6ae
    11 N77320208c35a46c9b5de927ce5aaf963
    12 N77f789d2426b4cf186ca0c970bd66ee5
    13 N87127f0f6c774c3f865995155290d2f7
    14 N93f8b9c9e6cf477dad92fac4122c32ce
    15 Ne33d8b1875ee49ce9fd9c1637c509ef9
    16 anzsrc-for:11
    17 anzsrc-for:1112
    18 schema:author N979385e451d44e139697a8af1f016d1d
    19 schema:citation sg:pub.10.1007/bf00316984
    20 sg:pub.10.1007/pl00009949
    21 sg:pub.10.1007/s005340050092
    22 sg:pub.10.1007/s005340050094
    23 sg:pub.10.1007/s005340050097
    24 https://app.dimensions.ai/details/publication/pub.1075519418
    25 https://app.dimensions.ai/details/publication/pub.1078393934
    26 https://app.dimensions.ai/details/publication/pub.1078400637
    27 https://doi.org/10.1001/archsurg.1995.01430100051011
    28 https://doi.org/10.1002/(sici)1097-0142(19981101)83:9<1923::aid-cncr7>3.0.co;2-#
    29 https://doi.org/10.1002/1097-0142(197701)39:1<232::aid-cncr2820390137>3.0.co;2-y
    30 https://doi.org/10.1002/1097-0142(19891201)64:11<2226::aid-cncr2820641107>3.0.co;2-1
    31 https://doi.org/10.1002/1097-0142(19951215)76:12<2449::aid-cncr2820761208>3.0.co;2-v
    32 https://doi.org/10.1002/bjs.1800831108
    33 https://doi.org/10.1002/jso.2930590111
    34 https://doi.org/10.1016/s0046-8177(88)80156-4
    35 https://doi.org/10.1016/s0748-7983(96)90853-7
    36 https://doi.org/10.1046/j.1365-2168.1998.00815.x
    37 https://doi.org/10.1097/00000658-199204000-00007
    38 https://doi.org/10.1097/00000658-199610000-00005
    39 https://doi.org/10.1097/00000658-199801000-00011
    40 https://doi.org/10.1111/j.1440-1746.1994.tb01271.x
    41 https://doi.org/10.1155/1992/93976
    42 schema:datePublished 2002-06
    43 schema:datePublishedReg 2002-06-01
    44 schema:description The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Two or more segmentectomies of the liver with systematic lymphadenectomy were performed in 18 patients. Resection of the extrahepatic bile duct was performed in 14 patients, and reconstruction of the portal vein was accomplished in 5 patients. Stage IVA or IVB tumors were seen in 13 patients, and lymph node (LN) metastasis was present in 14 patients. The estimated 5-year survival rate after surgery for mass-forming ICC was 28%, with median survival time of 18 months. In univariate analysis, five variables were determined to be significantly correlated with poor survival of patients with mass-forming ICC after surgery. These variables include mass-forming ICC with periductal infiltration, perineural invasion, portal vein invasion, presence of intrahepatic metastasis, and two or more LN metastases. Survival rates of 5 patients without LN metastasis and 6 patients with a single LN metastasis were 80% and 33% at 5 years, respectively, while 8 patients with two or more LN metastasis failed to survive beyond 2 years. Multivariate analysis revealed the presence of intrahepatic metastasis to be an independent prognostic factor of poor survival. Hepatectomy with resection of the extrahepatic bile duct and systematic lymphadenectomy yields a good chance for prolonged survival for patients with mass-forming ICC when the lesion is singular and LN metastasis is limited to a regional LN. Because the presence of intrahepatic metastasis was closely related to a poor prognosis in patients with mass-forming ICC, efficacious chemotherapy would be needed to control development of the lesion.
    45 schema:genre research_article
    46 schema:inLanguage en
    47 schema:isAccessibleForFree false
    48 schema:isPartOf N24392a599e374a4c9c094d1c6fd894a6
    49 N7f66a36cf9c64defb69582d45681e249
    50 sg:journal.1086446
    51 schema:name Clinicopathological prognostic factors and impact of surgical treatment of mass-forming intrahepatic cholangiocarcinoma
    52 schema:pagination 687-693
    53 schema:productId N08648a92e2c94b0897cb1c70571ff07b
    54 N2f1cde8dbfe04778a58f3ff608b7c978
    55 N70297f0ee56444c39f2482ea69270683
    56 Nab61a9fe220145669a787cff367e371b
    57 Nbe1a381110a14efcafc290ca547d9384
    58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004801848
    59 https://doi.org/10.1007/s00268-001-0291-1
    60 schema:sdDatePublished 2019-04-11T14:33
    61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    62 schema:sdPublisher N63f41e9384a64867b5917583d07a482e
    63 schema:url http://link.springer.com/10.1007%2Fs00268-001-0291-1
    64 sgo:license sg:explorer/license/
    65 sgo:sdDataset articles
    66 rdf:type schema:ScholarlyArticle
    67 N01d6d5c509b94e9b9697c6c15f636f68 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    68 schema:name Neoplasm Invasiveness
    69 rdf:type schema:DefinedTerm
    70 N02dd8b457558437c8c5440035491a531 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    71 schema:name Liver Neoplasms
    72 rdf:type schema:DefinedTerm
    73 N08648a92e2c94b0897cb1c70571ff07b schema:name pubmed_id
    74 schema:value 12053220
    75 rdf:type schema:PropertyValue
    76 N141966e46ec240e3bc423d25c22f4813 rdf:first sg:person.01132117403.41
    77 rdf:rest N3b726495f0c14e26bece98ab446ed810
    78 N191f998a579f4a53b1d3c3f3198d18cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    79 schema:name Survivors
    80 rdf:type schema:DefinedTerm
    81 N24392a599e374a4c9c094d1c6fd894a6 schema:issueNumber 6
    82 rdf:type schema:PublicationIssue
    83 N2d758841ce244f098b612ae0bcd6c788 rdf:first sg:person.0730101772.16
    84 rdf:rest N88ff87d4ada0407b88179fd6e103eba2
    85 N2f1cde8dbfe04778a58f3ff608b7c978 schema:name nlm_unique_id
    86 schema:value 7704052
    87 rdf:type schema:PropertyValue
    88 N30870949f14845008942bf288d32f07c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    89 schema:name Female
    90 rdf:type schema:DefinedTerm
    91 N3b726495f0c14e26bece98ab446ed810 rdf:first sg:person.01356133636.70
    92 rdf:rest Ne9769eb55187430dade99019df360041
    93 N42641aee0d1045a593f8f343899bcec1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    94 schema:name Prognosis
    95 rdf:type schema:DefinedTerm
    96 N53c3771acec549008f932823cab16959 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    97 schema:name Neoplasm Recurrence, Local
    98 rdf:type schema:DefinedTerm
    99 N57a818b0c3e5441eb736848af7d3a3a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    100 schema:name Risk Factors
    101 rdf:type schema:DefinedTerm
    102 N5ba523a18bbc4e129583b4c7b30ac8d8 rdf:first sg:person.01226740305.50
    103 rdf:rest N141966e46ec240e3bc423d25c22f4813
    104 N5cc003eaa77e43d7b78ac24821f558e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    105 schema:name Cholangiocarcinoma
    106 rdf:type schema:DefinedTerm
    107 N63f41e9384a64867b5917583d07a482e schema:name Springer Nature - SN SciGraph project
    108 rdf:type schema:Organization
    109 N6a7299b8005b4c56805488668e68fe1c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    110 schema:name Humans
    111 rdf:type schema:DefinedTerm
    112 N6f46cbf7d8784c1d9b37c9e482b4b6ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    113 schema:name Survival Analysis
    114 rdf:type schema:DefinedTerm
    115 N70297f0ee56444c39f2482ea69270683 schema:name dimensions_id
    116 schema:value pub.1004801848
    117 rdf:type schema:PropertyValue
    118 N77320208c35a46c9b5de927ce5aaf963 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    119 schema:name Hepatectomy
    120 rdf:type schema:DefinedTerm
    121 N77f789d2426b4cf186ca0c970bd66ee5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    122 schema:name Retrospective Studies
    123 rdf:type schema:DefinedTerm
    124 N7f66a36cf9c64defb69582d45681e249 schema:volumeNumber 26
    125 rdf:type schema:PublicationVolume
    126 N870dcee769024981b08db28982fac210 rdf:first sg:person.01252464703.38
    127 rdf:rest N2d758841ce244f098b612ae0bcd6c788
    128 N87127f0f6c774c3f865995155290d2f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    129 schema:name Male
    130 rdf:type schema:DefinedTerm
    131 N88ff87d4ada0407b88179fd6e103eba2 rdf:first sg:person.015605373132.05
    132 rdf:rest Nedd180a2c52b46b1a9c62145ed829f04
    133 N93f8b9c9e6cf477dad92fac4122c32ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    134 schema:name Aged
    135 rdf:type schema:DefinedTerm
    136 N979385e451d44e139697a8af1f016d1d rdf:first sg:person.016543515244.33
    137 rdf:rest Ncf51de86310748f3bb81703adcd4f56f
    138 Nab61a9fe220145669a787cff367e371b schema:name doi
    139 schema:value 10.1007/s00268-001-0291-1
    140 rdf:type schema:PropertyValue
    141 Nbe1a381110a14efcafc290ca547d9384 schema:name readcube_id
    142 schema:value 16e15ca0558e978707b66d40089b3c88c22d95de06532fcf76418b7f35230fa7
    143 rdf:type schema:PropertyValue
    144 Ncf51de86310748f3bb81703adcd4f56f rdf:first sg:person.0733465475.45
    145 rdf:rest N5ba523a18bbc4e129583b4c7b30ac8d8
    146 Ne33d8b1875ee49ce9fd9c1637c509ef9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    147 schema:name Middle Aged
    148 rdf:type schema:DefinedTerm
    149 Ne9769eb55187430dade99019df360041 rdf:first sg:person.01136236303.05
    150 rdf:rest N870dcee769024981b08db28982fac210
    151 Nedd180a2c52b46b1a9c62145ed829f04 rdf:first sg:person.015555041242.12
    152 rdf:rest rdf:nil
    153 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    154 schema:name Medical and Health Sciences
    155 rdf:type schema:DefinedTerm
    156 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    157 schema:name Oncology and Carcinogenesis
    158 rdf:type schema:DefinedTerm
    159 sg:journal.1086446 schema:issn 0364-2313
    160 1432-2323
    161 schema:name World Journal of Surgery
    162 rdf:type schema:Periodical
    163 sg:person.01132117403.41 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    164 schema:familyName Okamoto
    165 schema:givenName Kazuya
    166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132117403.41
    167 rdf:type schema:Person
    168 sg:person.01136236303.05 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    169 schema:familyName Tsuchiya
    170 schema:givenName Yasuo
    171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136236303.05
    172 rdf:type schema:Person
    173 sg:person.01226740305.50 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    174 schema:familyName Yokoi
    175 schema:givenName Yoshihiro
    176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226740305.50
    177 rdf:type schema:Person
    178 sg:person.01252464703.38 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    179 schema:familyName Okumura
    180 schema:givenName Takuya
    181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252464703.38
    182 rdf:type schema:Person
    183 sg:person.01356133636.70 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    184 schema:familyName Kurachi
    185 schema:givenName Kiyotaka
    186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356133636.70
    187 rdf:type schema:Person
    188 sg:person.015555041242.12 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    189 schema:familyName Nakamura
    190 schema:givenName Satoshi
    191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015555041242.12
    192 rdf:type schema:Person
    193 sg:person.015605373132.05 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    194 schema:familyName Baba
    195 schema:givenName Satoshi
    196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015605373132.05
    197 rdf:type schema:Person
    198 sg:person.016543515244.33 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    199 schema:familyName Suzuki
    200 schema:givenName Shohachi
    201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016543515244.33
    202 rdf:type schema:Person
    203 sg:person.0730101772.16 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    204 schema:familyName Konno
    205 schema:givenName Hiroyuki
    206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730101772.16
    207 rdf:type schema:Person
    208 sg:person.0733465475.45 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
    209 schema:familyName Sakaguchi
    210 schema:givenName Takanori
    211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733465475.45
    212 rdf:type schema:Person
    213 sg:pub.10.1007/bf00316984 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037973793
    214 https://doi.org/10.1007/bf00316984
    215 rdf:type schema:CreativeWork
    216 sg:pub.10.1007/pl00009949 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043509058
    217 https://doi.org/10.1007/pl00009949
    218 rdf:type schema:CreativeWork
    219 sg:pub.10.1007/s005340050092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014759806
    220 https://doi.org/10.1007/s005340050092
    221 rdf:type schema:CreativeWork
    222 sg:pub.10.1007/s005340050094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026704955
    223 https://doi.org/10.1007/s005340050094
    224 rdf:type schema:CreativeWork
    225 sg:pub.10.1007/s005340050097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018557923
    226 https://doi.org/10.1007/s005340050097
    227 rdf:type schema:CreativeWork
    228 https://app.dimensions.ai/details/publication/pub.1075519418 schema:CreativeWork
    229 https://app.dimensions.ai/details/publication/pub.1078393934 schema:CreativeWork
    230 https://app.dimensions.ai/details/publication/pub.1078400637 schema:CreativeWork
    231 https://doi.org/10.1001/archsurg.1995.01430100051011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026507049
    232 rdf:type schema:CreativeWork
    233 https://doi.org/10.1002/(sici)1097-0142(19981101)83:9<1923::aid-cncr7>3.0.co;2-# schema:sameAs https://app.dimensions.ai/details/publication/pub.1024123175
    234 rdf:type schema:CreativeWork
    235 https://doi.org/10.1002/1097-0142(197701)39:1<232::aid-cncr2820390137>3.0.co;2-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1007431890
    236 rdf:type schema:CreativeWork
    237 https://doi.org/10.1002/1097-0142(19891201)64:11<2226::aid-cncr2820641107>3.0.co;2-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003826236
    238 rdf:type schema:CreativeWork
    239 https://doi.org/10.1002/1097-0142(19951215)76:12<2449::aid-cncr2820761208>3.0.co;2-v schema:sameAs https://app.dimensions.ai/details/publication/pub.1035044975
    240 rdf:type schema:CreativeWork
    241 https://doi.org/10.1002/bjs.1800831108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017704377
    242 rdf:type schema:CreativeWork
    243 https://doi.org/10.1002/jso.2930590111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051295820
    244 rdf:type schema:CreativeWork
    245 https://doi.org/10.1016/s0046-8177(88)80156-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014348394
    246 rdf:type schema:CreativeWork
    247 https://doi.org/10.1016/s0748-7983(96)90853-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030817398
    248 rdf:type schema:CreativeWork
    249 https://doi.org/10.1046/j.1365-2168.1998.00815.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017420888
    250 rdf:type schema:CreativeWork
    251 https://doi.org/10.1097/00000658-199204000-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028029505
    252 rdf:type schema:CreativeWork
    253 https://doi.org/10.1097/00000658-199610000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060134367
    254 rdf:type schema:CreativeWork
    255 https://doi.org/10.1097/00000658-199801000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060134679
    256 rdf:type schema:CreativeWork
    257 https://doi.org/10.1111/j.1440-1746.1994.tb01271.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1011117396
    258 rdf:type schema:CreativeWork
    259 https://doi.org/10.1155/1992/93976 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040346068
    260 rdf:type schema:CreativeWork
    261 https://www.grid.ac/institutes/grid.411951.9 schema:alternateName Hamamatsu University
    262 schema:name Department of Pathology II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan
    263 Department of Surgery II, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan
    264 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...