Matrix metalloproteinases in patients with osteoarthritis of the hip View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2000-05

AUTHORS

K. Masuhara, S. Bak Lee, T. Nakai, N. Sugano, T. Ochi, Y. Sasaguri

ABSTRACT

In 78 patients undergoing a total hip replacement we examined the production of matrix metalloproteinases (MMP) by the fibroblasts from the connective tissue of the acetabulum; we then correlated these findings with clinical and radiological characteristics of the same patients. In 53 patients only MMP-2 was produced; in 15 cases MMP-1, -2 and -3 were present; and in 10 cases not only MMP-1, -2, -3 but also MMP-9. Significant differences among the clinical and radiological parameters were found in the 3 subsets. A positive correlation between the production of MMP-9 and a rapid destruction of the hip joint was found. More... »

PAGES

92-96

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s002640000110

DOI

http://dx.doi.org/10.1007/s002640000110

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006302394

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10894378


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