Immune checkpoint blockade therapy of mesothelioma: a clinical and radiological challenge View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-08

AUTHORS

Luana Calabrò, Aldo Morra, Robin Cornelissen, Joachim Aerts, Michele Maio

ABSTRACT

Treatment of malignant pleural mesothelioma (MPM) represents a highly unmet medical need. Here, we discuss the results and therapeutic potential of first- and second-generation immunomodulatory antibodies targeting distinct immune checkpoints for the treatment of MPM, as well as their prospective therapeutic role in combination strategies. We also discuss the role of appropriate radiological criteria of response for MPM and the potential need of ad hoc criteria of disease evaluation in MPM patients undergoing treatment with immunotherapeutic agents. More... »

PAGES

1317-1324

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00262-018-2191-3

DOI

http://dx.doi.org/10.1007/s00262-018-2191-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105126702

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29943157


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