Regulation of immunity and oncogenesis by the IRF transcription factor family View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-04

AUTHORS

David Savitsky, Tomohiko Tamura, Hideyuki Yanai, Tadatsugu Taniguchi

ABSTRACT

Nine interferon regulatory factors (IRFs) compose a family of transcription factors in mammals. Although this family was originally identified in the context of the type I interferon system, subsequent studies have revealed much broader functions performed by IRF members in host defense. In this review, we provide an update on the current knowledge of their roles in immune responses, immune cell development, and regulation of oncogenesis. More... »

PAGES

489-510

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00262-009-0804-6

    DOI

    http://dx.doi.org/10.1007/s00262-009-0804-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1046770909

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20049431


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