Ontology type: schema:ScholarlyArticle
1996-03
AUTHORSM. Okada, T. Shirotani, T. Sakurai, T. Yao, M. Seo, Y. Okada, K. Sakamoto, K. Tanaka
ABSTRACT.Background: To clarify the radiographic characteristics of intractable gastric ulcers with H2-receptor antagonists.Methods: The radiographic findings at the time of starting treatment were compared between 42 patients with gastric ulcers that did not heal within eight weeks of starting treatment with H2-receptor antagonists (the intractable group) and 58 patients whose ulcers healed within the eight-week period (the tractable group).Results: The following radiographic findings in the intractable group were observed at a significantly higher incidence than those in the tractable group and included: an ulcer located on the angle, linear ulcers, a greater depth, an uneven mound surrounding an ulcer, prominent folds' convergence, an overhanging gastric mucosa, an irregular ulcer base, a shortening of the lesser curvature and a U-shaped deformity of the angle. A multiple logistic regression analysis showed that the following three factors had a significant and independent delaying effect on healing: a U-shaped deformity of the angle, an uneven mound surrounding an ulcer and prominent folds' convergence. The relative risk of these factors were 12.7, 14.4 and 12.5, respectively.Conclusions: Intractable gastric ulcer with H2-receptor antagonists can be predicted based on the characteristic radiographic findings at the start of treatment. More... »
PAGES133-141
http://scigraph.springernature.com/pub.10.1007/s002619900028
DOIhttp://dx.doi.org/10.1007/s002619900028
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/8661758
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