Comparison of image noise and image quality between full-dose abdominal computed tomography scans reconstructed with weighted filtered back projection and ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-07-06

AUTHORS

Stephen Choy, Dennis Parhar, Kevin Lian, Heiko Schmiedeskamp, Luck Louis, Timothy O’Connell, Patrick McLaughlin, Savvas Nicolaou

ABSTRACT

PurposeTo retrospectively compare the image noise, signal-to-noise ratio (SNR), and subjective image quality between CT images acquired with a dual-source, split-dose imaging protocol reconstructed at full and half doses with weighted filtered back projection (wFBP) and an improved sinogram-affirmed iterative reconstruction algorithm (SAFIRE*).MethodsFifty-three consecutive patients underwent contrast-enhanced CT of the abdomen using a standardized dual-source, single energy CT protocol. Half-dose images were retrospectively generated using data from one detector only. Full-dose datasets were reconstructed with wFBP, while half-dose datasets were reconstructed with wFBP and SAFIRE* strengths 1–5. Region of interest analysis was performed to assess SNR and noise. Diagnostic acceptability, subjective noise, and spatial resolution were graded on a 10-point scale by two readers. Statistical analysis was carried out with repeated measures analysis of variance, Wilcoxon signed rank test, and Cohen’s κ test.ResultsWith the increasing strengths of SAFIRE*, a progressive reduction in noise and increase in SNR (p < 0.01) was observed. There was a statistically significant decrease in objective noise and increase in SNR in half-dose SAFIRE* strength 4 and 5 reconstructions compared to full-dose reconstructions using wFBP (p < 0.01). Qualitative analysis revealed a progressive increase in diagnostic acceptability, decrease in subjective noise and increase in spatial resolution for half-dose images reconstructed with the increasing strengths of SAFIRE* (p < 0.01).ConclusionsHalf-dose CT images reconstructed with SAFIRE* at strength 4 and 5 have superior image quality compared to full-dose images reconstructed with wFBP. SAFIRE* potentially allows dose reductions in the order of 50% over wFBP. More... »

PAGES

355-361

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00261-018-1687-9

DOI

http://dx.doi.org/10.1007/s00261-018-1687-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105338782

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29980828


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