Focal nodular hyperplasia: hepatobiliary enhancement patterns on gadoxetic-acid contrast-enhanced MRI View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-06

AUTHORS

C. S. van Kessel, E. de Boer, F. J. W. ten Kate, L. A. A. Brosens, W. B. Veldhuis, M. S. van Leeuwen

ABSTRACT

OBJECTIVES: To assess the range of hepatobiliary enhancement patterns of focal nodular hyperplasia (FNH) after gadoxetic-acid injection, and to correlate these patterns to specific histological features. MATERIALS AND METHODS: FNH lesions, imaged with Gadoxetic-acid-enhanced MRI, with either typical imaging findings on T1, T2 and dynamic-enhanced sequences or histologically proven, were evaluated for hepatobiliary enhancement patterns and categorized as homogeneously hyperintense, inhomogeneously hyperintense, iso-intense, or hypo-intense-with-ring. Available histological specimens of FNHs (surgical resection or histological biopsy), were re-evaluated to correlate histological features with observed enhancement patterns. RESULTS: 26 FNHs in 20 patients were included; histology was available in six lesions (four resections, two biopsies). The following distribution of enhancement patterns was observed: 10/26 homogeneously hyperintense, 4/26 inhomogeneously hyperintense, 5/26 iso-intense, 6/26 hypointense-with-ring, and 1/26 hypointense, but without enhancing ring. The following histological features associated with gadoxetic-acid uptake were identified: number and type of bile-ducts (pre-existent bile-ducts, proliferation, and metaplasia), extent of fibrosis, the presence of inflammation and extent of vascular proliferation. CONCLUSION: FNH lesions can be categorized into different hepatobiliary enhancement patterns on Gadoxetic-acid-enhanced MRI, which appear to be associated with histological differences in number and type of bile-ducts, and varying the presence of fibrous tissue, inflammation, and vascularization. More... »

PAGES

490-501

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00261-012-9916-0

DOI

http://dx.doi.org/10.1007/s00261-012-9916-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002346660

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22729462


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, CD34", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biliary Tract", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Contrast Media", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Focal Nodular Hyperplasia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gadolinium DTPA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Image Enhancement", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Imaging", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands", 
            "Department of Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Kessel", 
        "givenName": "C. S.", 
        "id": "sg:person.01256666363.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256666363.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Boer", 
        "givenName": "E.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kate", 
        "givenName": "F. J. W. ten", 
        "id": "sg:person.015064055466.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015064055466.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Brosens", 
        "givenName": "L. A. A.", 
        "id": "sg:person.07362307214.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07362307214.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Veldhuis", 
        "givenName": "W. B.", 
        "id": "sg:person.01121666652.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121666652.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Leeuwen", 
        "givenName": "M. S.", 
        "id": "sg:person.0667406735.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667406735.21"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s002689910059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002040921", 
          "https://doi.org/10.1007/s002689910059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1440-1746.2001.02576.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008268003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e3181705cd1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011901269"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e3181705cd1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011901269"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.suc.2010.04.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013238178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0344-0338(98)80117-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013530708"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0016-5085(90)91030-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014735486"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840050622", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019901477"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00261-001-0140-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021041467", 
          "https://doi.org/10.1007/s00261-001-0140-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.10091557", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023582676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-010-1775-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024112823", 
          "https://doi.org/10.1007/s00330-010-1775-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-010-1775-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024112823", 
          "https://doi.org/10.1007/s00330-010-1775-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0676.1989.tb00426.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024861327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0676.1989.tb00426.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024861327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/rg.241035050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029325825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02165858", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030921725", 
          "https://doi.org/10.1007/bf02165858"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02165858", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030921725", 
          "https://doi.org/10.1007/bf02165858"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-005-2668-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032058575", 
          "https://doi.org/10.1007/s00330-005-2668-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-005-2668-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032058575", 
          "https://doi.org/10.1007/s00330-005-2668-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-003-2089-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035230610", 
          "https://doi.org/10.1007/s00330-003-2089-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002689900337", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036966805", 
          "https://doi.org/10.1007/s002689900337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0676.1984.tb00955.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047374690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0676.1984.tb00955.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047374690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2000-7227", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057403551"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199912000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060123008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199912000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060123008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199912000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060123008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.170.2.9456952", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069321423"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.179.6.1791447", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069325108"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiology.184.3.1509052", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076826537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081668017", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiology.199.1.8633143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082886994"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-06", 
    "datePublishedReg": "2013-06-01", 
    "description": "OBJECTIVES: To assess the range of hepatobiliary enhancement patterns of focal nodular hyperplasia (FNH) after gadoxetic-acid injection, and to correlate these patterns to specific histological features.\nMATERIALS AND METHODS: FNH lesions, imaged with Gadoxetic-acid-enhanced MRI, with either typical imaging findings on T1, T2 and dynamic-enhanced sequences or histologically proven, were evaluated for hepatobiliary enhancement patterns and categorized as homogeneously hyperintense, inhomogeneously hyperintense, iso-intense, or hypo-intense-with-ring. Available histological specimens of FNHs (surgical resection or histological biopsy), were re-evaluated to correlate histological features with observed enhancement patterns.\nRESULTS: 26 FNHs in 20 patients were included; histology was available in six lesions (four resections, two biopsies). The following distribution of enhancement patterns was observed: 10/26 homogeneously hyperintense, 4/26 inhomogeneously hyperintense, 5/26 iso-intense, 6/26 hypointense-with-ring, and 1/26 hypointense, but without enhancing ring. The following histological features associated with gadoxetic-acid uptake were identified: number and type of bile-ducts (pre-existent bile-ducts, proliferation, and metaplasia), extent of fibrosis, the presence of inflammation and extent of vascular proliferation.\nCONCLUSION: FNH lesions can be categorized into different hepatobiliary enhancement patterns on Gadoxetic-acid-enhanced MRI, which appear to be associated with histological differences in number and type of bile-ducts, and varying the presence of fibrous tissue, inflammation, and vascularization.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00261-012-9916-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1297457", 
        "issn": [
          "2366-004X", 
          "2366-0058"
        ], 
        "name": "Abdominal Radiology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "38"
      }
    ], 
    "name": "Focal nodular hyperplasia: hepatobiliary enhancement patterns on gadoxetic-acid contrast-enhanced MRI", 
    "pagination": "490-501", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "0b2c250ddd2015b579c1f1cbb9aef94cc3badea1cad649fb22d2252ea3ef54ec"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "22729462"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9303672"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00261-012-9916-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1002346660"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00261-012-9916-0", 
      "https://app.dimensions.ai/details/publication/pub.1002346660"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:46", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000509.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00261-012-9916-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00261-012-9916-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00261-012-9916-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00261-012-9916-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00261-012-9916-0'


 

This table displays all metadata directly associated to this object as RDF triples.

223 TRIPLES      21 PREDICATES      63 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00261-012-9916-0 schema:about N0c7a8a34eb744898b51032a0307d8f2d
2 N19b0ac2068bd4a269c8f07ef3a778948
3 N45aee31e645847e29788526276d1de23
4 N5b6bb2c4c19c441386beb5f2cd358f96
5 N5c0978454dd24249a2bec60ef5ebb4fe
6 N82af58eb091648e3ba522a777d95a49d
7 Nc487c751e82443ceb39bb68207e41217
8 Nc517d04afcef4773b879600fcfb0f5e0
9 Nd690ca46047c41d591f6825decb6b571
10 Nf90727a5ad61445b8b106e52402500fd
11 anzsrc-for:11
12 anzsrc-for:1112
13 schema:author Ne5cbd9812d854ad787874242223d3479
14 schema:citation sg:pub.10.1007/bf02165858
15 sg:pub.10.1007/s00261-001-0140-6
16 sg:pub.10.1007/s002689900337
17 sg:pub.10.1007/s002689910059
18 sg:pub.10.1007/s00330-003-2089-z
19 sg:pub.10.1007/s00330-005-2668-2
20 sg:pub.10.1007/s00330-010-1775-x
21 https://app.dimensions.ai/details/publication/pub.1081668017
22 https://doi.org/10.1002/hep.1840050622
23 https://doi.org/10.1016/0016-5085(90)91030-a
24 https://doi.org/10.1016/j.suc.2010.04.006
25 https://doi.org/10.1016/s0344-0338(98)80117-9
26 https://doi.org/10.1046/j.1440-1746.2001.02576.x
27 https://doi.org/10.1055/s-2000-7227
28 https://doi.org/10.1097/00000478-199912000-00001
29 https://doi.org/10.1097/rli.0b013e3181705cd1
30 https://doi.org/10.1111/j.1600-0676.1984.tb00955.x
31 https://doi.org/10.1111/j.1600-0676.1989.tb00426.x
32 https://doi.org/10.1148/radiol.10091557
33 https://doi.org/10.1148/radiology.184.3.1509052
34 https://doi.org/10.1148/radiology.199.1.8633143
35 https://doi.org/10.1148/rg.241035050
36 https://doi.org/10.2214/ajr.170.2.9456952
37 https://doi.org/10.2214/ajr.179.6.1791447
38 schema:datePublished 2013-06
39 schema:datePublishedReg 2013-06-01
40 schema:description OBJECTIVES: To assess the range of hepatobiliary enhancement patterns of focal nodular hyperplasia (FNH) after gadoxetic-acid injection, and to correlate these patterns to specific histological features. MATERIALS AND METHODS: FNH lesions, imaged with Gadoxetic-acid-enhanced MRI, with either typical imaging findings on T1, T2 and dynamic-enhanced sequences or histologically proven, were evaluated for hepatobiliary enhancement patterns and categorized as homogeneously hyperintense, inhomogeneously hyperintense, iso-intense, or hypo-intense-with-ring. Available histological specimens of FNHs (surgical resection or histological biopsy), were re-evaluated to correlate histological features with observed enhancement patterns. RESULTS: 26 FNHs in 20 patients were included; histology was available in six lesions (four resections, two biopsies). The following distribution of enhancement patterns was observed: 10/26 homogeneously hyperintense, 4/26 inhomogeneously hyperintense, 5/26 iso-intense, 6/26 hypointense-with-ring, and 1/26 hypointense, but without enhancing ring. The following histological features associated with gadoxetic-acid uptake were identified: number and type of bile-ducts (pre-existent bile-ducts, proliferation, and metaplasia), extent of fibrosis, the presence of inflammation and extent of vascular proliferation. CONCLUSION: FNH lesions can be categorized into different hepatobiliary enhancement patterns on Gadoxetic-acid-enhanced MRI, which appear to be associated with histological differences in number and type of bile-ducts, and varying the presence of fibrous tissue, inflammation, and vascularization.
41 schema:genre research_article
42 schema:inLanguage en
43 schema:isAccessibleForFree true
44 schema:isPartOf N6197aefda64b4f559af83c89b2b5ee11
45 N767a08935ef64d768bc770c424846670
46 sg:journal.1297457
47 schema:name Focal nodular hyperplasia: hepatobiliary enhancement patterns on gadoxetic-acid contrast-enhanced MRI
48 schema:pagination 490-501
49 schema:productId N41bced58031242848faa26c5184fc078
50 N4ec5bdd7c4e24e9d989d7ad0d1d7a12b
51 N9be6c2731b274d8ebe03bb75a3aa89d8
52 Nd3514ec8f42f4e39be5893e161cd5b94
53 Nd41d64e9fd16408781543bd90a56b287
54 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002346660
55 https://doi.org/10.1007/s00261-012-9916-0
56 schema:sdDatePublished 2019-04-10T20:46
57 schema:sdLicense https://scigraph.springernature.com/explorer/license/
58 schema:sdPublisher N3fdd759897c04ffeaab614be0c54d0f8
59 schema:url http://link.springer.com/10.1007%2Fs00261-012-9916-0
60 sgo:license sg:explorer/license/
61 sgo:sdDataset articles
62 rdf:type schema:ScholarlyArticle
63 N0c7a8a34eb744898b51032a0307d8f2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
64 schema:name Image Enhancement
65 rdf:type schema:DefinedTerm
66 N19b0ac2068bd4a269c8f07ef3a778948 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Gadolinium DTPA
68 rdf:type schema:DefinedTerm
69 N365fb32686f84587bcb42cac4610e7ec rdf:first sg:person.015064055466.42
70 rdf:rest N8b88a85261eb42f998a776c734986ef1
71 N3fdd759897c04ffeaab614be0c54d0f8 schema:name Springer Nature - SN SciGraph project
72 rdf:type schema:Organization
73 N41bced58031242848faa26c5184fc078 schema:name doi
74 schema:value 10.1007/s00261-012-9916-0
75 rdf:type schema:PropertyValue
76 N45aee31e645847e29788526276d1de23 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Immunohistochemistry
78 rdf:type schema:DefinedTerm
79 N4ec5bdd7c4e24e9d989d7ad0d1d7a12b schema:name nlm_unique_id
80 schema:value 9303672
81 rdf:type schema:PropertyValue
82 N5b6bb2c4c19c441386beb5f2cd358f96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Contrast Media
84 rdf:type schema:DefinedTerm
85 N5c0978454dd24249a2bec60ef5ebb4fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Humans
87 rdf:type schema:DefinedTerm
88 N6197aefda64b4f559af83c89b2b5ee11 schema:issueNumber 3
89 rdf:type schema:PublicationIssue
90 N69db3bbd932f40a098728ae735d17ef9 rdf:first Nc36394ee3c31498b94d7c9a5a9795e35
91 rdf:rest N365fb32686f84587bcb42cac4610e7ec
92 N767a08935ef64d768bc770c424846670 schema:volumeNumber 38
93 rdf:type schema:PublicationVolume
94 N82af58eb091648e3ba522a777d95a49d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Magnetic Resonance Imaging
96 rdf:type schema:DefinedTerm
97 N8b88a85261eb42f998a776c734986ef1 rdf:first sg:person.07362307214.20
98 rdf:rest Nf2947101de6e405da4cc4949f0345c87
99 N9be6c2731b274d8ebe03bb75a3aa89d8 schema:name pubmed_id
100 schema:value 22729462
101 rdf:type schema:PropertyValue
102 Nc36394ee3c31498b94d7c9a5a9795e35 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
103 schema:familyName de Boer
104 schema:givenName E.
105 rdf:type schema:Person
106 Nc487c751e82443ceb39bb68207e41217 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Focal Nodular Hyperplasia
108 rdf:type schema:DefinedTerm
109 Nc517d04afcef4773b879600fcfb0f5e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Biliary Tract
111 rdf:type schema:DefinedTerm
112 Nd3514ec8f42f4e39be5893e161cd5b94 schema:name dimensions_id
113 schema:value pub.1002346660
114 rdf:type schema:PropertyValue
115 Nd41d64e9fd16408781543bd90a56b287 schema:name readcube_id
116 schema:value 0b2c250ddd2015b579c1f1cbb9aef94cc3badea1cad649fb22d2252ea3ef54ec
117 rdf:type schema:PropertyValue
118 Nd690ca46047c41d591f6825decb6b571 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Antigens, CD34
120 rdf:type schema:DefinedTerm
121 Nd9e20f76a7d540348c53bacda4f9284e rdf:first sg:person.0667406735.21
122 rdf:rest rdf:nil
123 Ne5cbd9812d854ad787874242223d3479 rdf:first sg:person.01256666363.77
124 rdf:rest N69db3bbd932f40a098728ae735d17ef9
125 Nf2947101de6e405da4cc4949f0345c87 rdf:first sg:person.01121666652.18
126 rdf:rest Nd9e20f76a7d540348c53bacda4f9284e
127 Nf90727a5ad61445b8b106e52402500fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Liver
129 rdf:type schema:DefinedTerm
130 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
131 schema:name Medical and Health Sciences
132 rdf:type schema:DefinedTerm
133 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
134 schema:name Oncology and Carcinogenesis
135 rdf:type schema:DefinedTerm
136 sg:journal.1297457 schema:issn 2366-004X
137 2366-0058
138 schema:name Abdominal Radiology
139 rdf:type schema:Periodical
140 sg:person.01121666652.18 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
141 schema:familyName Veldhuis
142 schema:givenName W. B.
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121666652.18
144 rdf:type schema:Person
145 sg:person.01256666363.77 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
146 schema:familyName van Kessel
147 schema:givenName C. S.
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256666363.77
149 rdf:type schema:Person
150 sg:person.015064055466.42 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
151 schema:familyName Kate
152 schema:givenName F. J. W. ten
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015064055466.42
154 rdf:type schema:Person
155 sg:person.0667406735.21 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
156 schema:familyName van Leeuwen
157 schema:givenName M. S.
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667406735.21
159 rdf:type schema:Person
160 sg:person.07362307214.20 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
161 schema:familyName Brosens
162 schema:givenName L. A. A.
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07362307214.20
164 rdf:type schema:Person
165 sg:pub.10.1007/bf02165858 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030921725
166 https://doi.org/10.1007/bf02165858
167 rdf:type schema:CreativeWork
168 sg:pub.10.1007/s00261-001-0140-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021041467
169 https://doi.org/10.1007/s00261-001-0140-6
170 rdf:type schema:CreativeWork
171 sg:pub.10.1007/s002689900337 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036966805
172 https://doi.org/10.1007/s002689900337
173 rdf:type schema:CreativeWork
174 sg:pub.10.1007/s002689910059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002040921
175 https://doi.org/10.1007/s002689910059
176 rdf:type schema:CreativeWork
177 sg:pub.10.1007/s00330-003-2089-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1035230610
178 https://doi.org/10.1007/s00330-003-2089-z
179 rdf:type schema:CreativeWork
180 sg:pub.10.1007/s00330-005-2668-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032058575
181 https://doi.org/10.1007/s00330-005-2668-2
182 rdf:type schema:CreativeWork
183 sg:pub.10.1007/s00330-010-1775-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024112823
184 https://doi.org/10.1007/s00330-010-1775-x
185 rdf:type schema:CreativeWork
186 https://app.dimensions.ai/details/publication/pub.1081668017 schema:CreativeWork
187 https://doi.org/10.1002/hep.1840050622 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019901477
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/0016-5085(90)91030-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1014735486
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/j.suc.2010.04.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013238178
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/s0344-0338(98)80117-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013530708
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1046/j.1440-1746.2001.02576.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008268003
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1055/s-2000-7227 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057403551
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1097/00000478-199912000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060123008
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1097/rli.0b013e3181705cd1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011901269
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1111/j.1600-0676.1984.tb00955.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1047374690
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1111/j.1600-0676.1989.tb00426.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024861327
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1148/radiol.10091557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023582676
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1148/radiology.184.3.1509052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076826537
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1148/radiology.199.1.8633143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082886994
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1148/rg.241035050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029325825
214 rdf:type schema:CreativeWork
215 https://doi.org/10.2214/ajr.170.2.9456952 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069321423
216 rdf:type schema:CreativeWork
217 https://doi.org/10.2214/ajr.179.6.1791447 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069325108
218 rdf:type schema:CreativeWork
219 https://www.grid.ac/institutes/grid.7692.a schema:alternateName University Medical Center Utrecht
220 schema:name Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
221 Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
222 Department of Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
223 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...