Diagnostic accuracy of CT colonography and optical colonoscopy evaluated using surgically resected specimens View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-07-09

AUTHORS

Yutaka J. Kawamura, Shinichiro Okada, Junichi Sasaki, Naoshi Tajima, Osamu Tanaka, Fumio Konishi

ABSTRACT

ObjectiveThe aim of this study was to clarify the diagnostic ability of CT colonography (CTC) using surgically resected specimens to avoid inaccuracy associated with optical colonoscopy (OC).Subjects and methodsCTC and OC were performed in 152 consecutive patients with colorectal cancer. Forty patients had simultaneous lesions other than the ones for which the surgery was intended, and these lesions were used as the gold standard. In 24 patients without stenosis, the sensitivity and positive predictive values (PPV) of CTC and OC were evaluated. In 16 patients with stenosis, the diagnostic ability of CTC for lesions located proximal to the stenosis was assessed.ResultsSensitivity of CTC and OC was 81% and 66% (P = 0.16), and PPV was 90% and 100% (P = 0.13), respectively. For 22 lesions larger than 5 mm, the sensitivity of CTC and OCS was 96% and 91% (P > 0.50), and PPV was 100% and 100%, respectively. In patients with stenosis, sensitivity and PPV were 89% and 80%, respectively. These results were not significantly different from those in patients without stenosis.ConclusionsCTC is a reliable modality for the diagnosis of colorectal polyps. It is also useful to evaluate the colon proximal to severe stenosis which could not be observed by OC. More... »

PAGES

584-588

References to SciGraph publications

  • 1999-01-01. The colonoscopic miss rate and true one-year recurrence of colorectal neoplastic polyps in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2006-02-01. Polyp Miss Rate Determined by Tandem Colonoscopy: A Systematic Review in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2002-12-01. Colonoscopic miss rates determined by direct comparison of colonoscopy with colon resection specimens in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00261-009-9558-z

    DOI

    http://dx.doi.org/10.1007/s00261-009-9558-z

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1049397382

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19588188


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