Use of iodine-123 metaiodobenzylguanidine scintigraphy to assess cardiac sympathetic denervation and the impact of hypertension in patients with non-insulin-dependent diabetes ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-09

AUTHORS

Koji Tamura, Keita Utsunomiya, Yuko Nakatani, Yoshinori Saika, Satoshi Onishi, Toshiji Iwasaka

ABSTRACT

. The objectives of this clinical study using iodine-123 metaiodobenzylguanidine (MIBG) scintigraphy were (a) to evaluate cardiac sympathetic denervation in non-insulin-dependent diabetes mellitus (NIDDM) patients with and without hypertension and (b) to investigate the relation between cardiac sympathetic denervation and prognosis in NIDDM patients. We compared clinical characteristics and MIBG data [heart to mediastinum (H/M) ratio and % washout rate (WR)] in a control group and NIDDM patients with and without hypertension. MIBG scintigraphy was performed in 11 controls and 82 NIDDM patients without overt cardiovascular disease except for hypertension (systolic blood pressure ≥140 and/or diastolic blood pressure ≥90 mmHg). After MIBG examination, blood pressure was measured regularly in all NIDDM patients. There were significant differences between 65 normotensive and 17 hypertensive NIDDM patients with respect to age (55±11 vs 63±12 years, respectively, P<0.05), prevalence of diabetic retinopathy (12% vs 35%, respectively, P<0.05) and systolic blood pressure (120±12 vs 145±16 mmHg, respectively, P<0.001). The H/M ratio in hypertensive NIDDM patients was significantly lower than in the control group (1.81±0.29 vs 2.27±0.20, respectively, P<0.01). During the follow-up period (18± 12 months), 17 NIDDM patients newly developed hypertension after MIBG examination. There were no significant differences in their clinical characteristics compared with persistently normotensive or hypertensive NIDDM patients. %WR in patients with new onset hypertension was significantly higher than in the control group (30.88%±16.87% vs 12.89%±11.94%, respectively, P<0.05). Moreover, in these patients %WR correlated with duration from the date of MIBG scintigraphy to the onset of hypertension (r=-0.512, P<0.05). Five NIDDM patients died during the follow-up period (four newly hypertensive patients and one normotensive patient). There were significant statistical differences between the control group and non-survivors in terms of age (54±11 vs 73±11 years, respectively, P<0.01), H/M ratio (2.27± 0.20 vs 1.64±0.36, respectively, P<0.01) and %WR (12.89%±11.94% vs 42.52%±22.39%, respectively, P<0.01). In conclusion, cardiac sympathetic denervation using MIBG scintigraphy observed in hypertensive NIDDM patients, and was more profound in non-survivors. MIBG scintigraphy proved useful for the evaluation of NIDDM patients with new onset hypertension, and it was found that NIDDM patients with abnormalities on MIBG scintigraphy needed to be observe carefully. More... »

PAGES

1310-1316

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s002590050588

DOI

http://dx.doi.org/10.1007/s002590050588

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040674720

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10541830


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "3-Iodobenzylguanidine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Autonomic Nervous System Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Pressure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Body Mass Index", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus, Type 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hemoglobin A", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypertension", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Radionuclide Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Radiopharmaceuticals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sympathetic Nervous System", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, Keihanna Hospital, Hirakata City, Osaka, Japan, JP", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Internal Medicine, Keihanna Hospital, Hirakata City, Osaka, Japan, JP"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tamura", 
        "givenName": "Koji", 
        "id": "sg:person.01016424677.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016424677.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Radiology, Keihanna Hospital, Hirakata city, Japan, JP", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Radiology, Keihanna Hospital, Hirakata city, Japan, JP"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Utsunomiya", 
        "givenName": "Keita", 
        "id": "sg:person.01147716751.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147716751.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, Keihanna Hospital, Hirakata City, Osaka, Japan, JP", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Internal Medicine, Keihanna Hospital, Hirakata City, Osaka, Japan, JP"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakatani", 
        "givenName": "Yuko", 
        "id": "sg:person.01006067432.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006067432.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Radiology, Keihanna Hospital, Hirakata city, Japan, JP", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Radiology, Keihanna Hospital, Hirakata city, Japan, JP"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saika", 
        "givenName": "Yoshinori", 
        "id": "sg:person.0714253726.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0714253726.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, Keihanna Hospital, Hirakata City, Osaka, Japan, JP", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Internal Medicine, Keihanna Hospital, Hirakata City, Osaka, Japan, JP"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Onishi", 
        "givenName": "Satoshi", 
        "id": "sg:person.01236544432.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236544432.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cardiovascular Center, Kansai Medical University, Osaka, Japan, JP", 
          "id": "http://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "Cardiovascular Center, Kansai Medical University, Osaka, Japan, JP"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwasaka", 
        "givenName": "Toshiji", 
        "id": "sg:person.01027604020.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027604020.40"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00843703", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026377699", 
          "https://doi.org/10.1007/bf00843703"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00399929", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020782741", 
          "https://doi.org/10.1007/bf00399929"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00401768", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029782596", 
          "https://doi.org/10.1007/bf00401768"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1999-09", 
    "datePublishedReg": "1999-09-01", 
    "description": "Abstract. The objectives of this clinical study using iodine-123 metaiodobenzylguanidine (MIBG) scintigraphy were (a) to evaluate cardiac sympathetic denervation in non-insulin-dependent diabetes mellitus (NIDDM) patients with and without hypertension and (b) to investigate the relation between cardiac sympathetic denervation and prognosis in NIDDM patients. We compared clinical characteristics and MIBG data [heart to mediastinum (H/M) ratio and % washout rate (WR)] in a control group and NIDDM patients with and without hypertension. MIBG scintigraphy was performed in 11 controls and 82 NIDDM patients without overt cardiovascular disease except for hypertension (systolic blood pressure \u2265140 and/or diastolic blood pressure \u226590 mmHg). After MIBG examination, blood pressure was measured regularly in all NIDDM patients. There were significant differences between 65 normotensive and 17 hypertensive NIDDM patients with respect to age (55\u00b111 vs 63\u00b112 years, respectively, P<0.05), prevalence of diabetic retinopathy (12% vs 35%, respectively, P<0.05) and systolic blood pressure (120\u00b112 vs 145\u00b116 mmHg, respectively, P<0.001). The H/M ratio in hypertensive NIDDM patients was significantly lower than in the control group (1.81\u00b10.29 vs 2.27\u00b10.20, respectively, P<0.01). During the follow-up period (18\u00b1 12 months), 17 NIDDM patients newly developed hypertension after MIBG examination. There were no significant differences in their clinical characteristics compared with persistently normotensive or hypertensive NIDDM patients. %WR in patients with new onset hypertension was significantly higher than in the control group (30.88%\u00b116.87% vs 12.89%\u00b111.94%, respectively, P<0.05). Moreover, in these patients %WR correlated with duration from the date of MIBG scintigraphy to the onset of hypertension (r=-0.512, P<0.05). Five NIDDM patients died during the follow-up period (four newly hypertensive patients and one normotensive patient). There were significant statistical differences between the control group and non-survivors in terms of age (54\u00b111 vs 73\u00b111 years, respectively, P<0.01), H/M ratio (2.27\u00b1 0.20 vs 1.64\u00b10.36, respectively, P<0.01) and %WR (12.89%\u00b111.94% vs 42.52%\u00b122.39%, respectively, P<0.01). In conclusion, cardiac sympathetic denervation using MIBG scintigraphy observed in hypertensive NIDDM patients, and was more profound in non-survivors. MIBG scintigraphy proved useful for the evaluation of NIDDM patients with new onset hypertension, and it was found that NIDDM patients with abnormalities on MIBG scintigraphy needed to be observe carefully.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s002590050588", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1297401", 
        "issn": [
          "1619-7070", 
          "1619-7089"
        ], 
        "name": "European Journal of Nuclear Medicine and Molecular Imaging", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "keywords": [
      "cardiac sympathetic denervation", 
      "hypertensive NIDDM patients", 
      "iodine-123 metaiodobenzylguanidine scintigraphy", 
      "NIDDM patients", 
      "MIBG scintigraphy", 
      "new onset hypertension", 
      "sympathetic denervation", 
      "control group", 
      "MIBG examinations", 
      "metaiodobenzylguanidine scintigraphy", 
      "clinical characteristics", 
      "blood pressure", 
      "onset hypertension", 
      "dependent diabetes mellitus (NIDDM) patients", 
      "overt cardiovascular disease", 
      "systolic blood pressure", 
      "impact of hypertension", 
      "diabetes mellitus patients", 
      "onset of hypertension", 
      "dependent diabetes mellitus", 
      "significant differences", 
      "terms of age", 
      "MIBG data", 
      "mellitus patients", 
      "diabetes mellitus", 
      "diabetic retinopathy", 
      "cardiovascular disease", 
      "hypertension", 
      "significant statistical difference", 
      "clinical studies", 
      "scintigraphy", 
      "patients", 
      "denervation", 
      "statistical difference", 
      "age", 
      "group", 
      "examination", 
      "mellitus", 
      "retinopathy", 
      "prognosis", 
      "prevalence", 
      "abnormalities", 
      "disease", 
      "differences", 
      "period", 
      "onset", 
      "duration", 
      "conclusion", 
      "pressure", 
      "control", 
      "study", 
      "evaluation", 
      "ratio", 
      "date", 
      "WR", 
      "objective", 
      "use", 
      "characteristics", 
      "data", 
      "impact", 
      "relation", 
      "respect", 
      "terms"
    ], 
    "name": "Use of iodine-123 metaiodobenzylguanidine scintigraphy to assess cardiac sympathetic denervation and the impact of hypertension in patients with non-insulin-dependent diabetes mellitus", 
    "pagination": "1310-1316", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1040674720"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s002590050588"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10541830"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s002590050588", 
      "https://app.dimensions.ai/details/publication/pub.1040674720"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:13", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_332.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s002590050588"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s002590050588'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s002590050588'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s002590050588'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s002590050588'


 

This table displays all metadata directly associated to this object as RDF triples.

261 TRIPLES      22 PREDICATES      114 URIs      102 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s002590050588 schema:about N11fe3aa54bc94a0a9148549d9d59a526
2 N1801620c8d6a433bbd28b2cf391b989f
3 N3bf279ce2eec49809c7597614860f51e
4 N51670ad1cd3f424ebba4ae54934d03c4
5 N555461ef8d654b09b32e49d9525e1727
6 N5d6e37338ebb46328483bfc5264cba16
7 N62900bc5b6a743fc85cc8fcc32a390ca
8 N78ab61ed441f4507b7575ff50ce69ab0
9 N799abb5c5b7141e48c532d0785c2115e
10 N84174a358fb5416584573e89e9a570e2
11 N8cb859709f394b55b162e7f70a333ce9
12 N8e77bf15026c431fb36fa9865470b62e
13 N98e36026a9644382ac2bae22c6e19d84
14 Nb3d9cdcdc90e43da8c72e535efd13e72
15 Nbafcfa53c482436da69cce02910f15c2
16 Nce01cab07f8b4aabbb80c58a3f24ccde
17 Nd5cf4d3fde724978bf13fa6442489128
18 Nd604bc4be0834e56aa9c4040256fea02
19 Nde347e36df6c444090378ed64f3f5744
20 Nf7ae94d909ad4c878c1c1414e7f00bac
21 anzsrc-for:11
22 anzsrc-for:1102
23 anzsrc-for:1103
24 schema:author Ne2929b3facd546188dc6fedf47fab569
25 schema:citation sg:pub.10.1007/bf00399929
26 sg:pub.10.1007/bf00401768
27 sg:pub.10.1007/bf00843703
28 schema:datePublished 1999-09
29 schema:datePublishedReg 1999-09-01
30 schema:description Abstract. The objectives of this clinical study using iodine-123 metaiodobenzylguanidine (MIBG) scintigraphy were (a) to evaluate cardiac sympathetic denervation in non-insulin-dependent diabetes mellitus (NIDDM) patients with and without hypertension and (b) to investigate the relation between cardiac sympathetic denervation and prognosis in NIDDM patients. We compared clinical characteristics and MIBG data [heart to mediastinum (H/M) ratio and % washout rate (WR)] in a control group and NIDDM patients with and without hypertension. MIBG scintigraphy was performed in 11 controls and 82 NIDDM patients without overt cardiovascular disease except for hypertension (systolic blood pressure ≥140 and/or diastolic blood pressure ≥90 mmHg). After MIBG examination, blood pressure was measured regularly in all NIDDM patients. There were significant differences between 65 normotensive and 17 hypertensive NIDDM patients with respect to age (55±11 vs 63±12 years, respectively, P<0.05), prevalence of diabetic retinopathy (12% vs 35%, respectively, P<0.05) and systolic blood pressure (120±12 vs 145±16 mmHg, respectively, P<0.001). The H/M ratio in hypertensive NIDDM patients was significantly lower than in the control group (1.81±0.29 vs 2.27±0.20, respectively, P<0.01). During the follow-up period (18± 12 months), 17 NIDDM patients newly developed hypertension after MIBG examination. There were no significant differences in their clinical characteristics compared with persistently normotensive or hypertensive NIDDM patients. %WR in patients with new onset hypertension was significantly higher than in the control group (30.88%±16.87% vs 12.89%±11.94%, respectively, P<0.05). Moreover, in these patients %WR correlated with duration from the date of MIBG scintigraphy to the onset of hypertension (r=-0.512, P<0.05). Five NIDDM patients died during the follow-up period (four newly hypertensive patients and one normotensive patient). There were significant statistical differences between the control group and non-survivors in terms of age (54±11 vs 73±11 years, respectively, P<0.01), H/M ratio (2.27± 0.20 vs 1.64±0.36, respectively, P<0.01) and %WR (12.89%±11.94% vs 42.52%±22.39%, respectively, P<0.01). In conclusion, cardiac sympathetic denervation using MIBG scintigraphy observed in hypertensive NIDDM patients, and was more profound in non-survivors. MIBG scintigraphy proved useful for the evaluation of NIDDM patients with new onset hypertension, and it was found that NIDDM patients with abnormalities on MIBG scintigraphy needed to be observe carefully.
31 schema:genre article
32 schema:inLanguage en
33 schema:isAccessibleForFree false
34 schema:isPartOf N1b0d1849373749408a5e9909f78e4e93
35 N6927b93ac3d0491f840a29296dd7341f
36 sg:journal.1297401
37 schema:keywords MIBG data
38 MIBG examinations
39 MIBG scintigraphy
40 NIDDM patients
41 WR
42 abnormalities
43 age
44 blood pressure
45 cardiac sympathetic denervation
46 cardiovascular disease
47 characteristics
48 clinical characteristics
49 clinical studies
50 conclusion
51 control
52 control group
53 data
54 date
55 denervation
56 dependent diabetes mellitus
57 dependent diabetes mellitus (NIDDM) patients
58 diabetes mellitus
59 diabetes mellitus patients
60 diabetic retinopathy
61 differences
62 disease
63 duration
64 evaluation
65 examination
66 group
67 hypertension
68 hypertensive NIDDM patients
69 impact
70 impact of hypertension
71 iodine-123 metaiodobenzylguanidine scintigraphy
72 mellitus
73 mellitus patients
74 metaiodobenzylguanidine scintigraphy
75 new onset hypertension
76 objective
77 onset
78 onset hypertension
79 onset of hypertension
80 overt cardiovascular disease
81 patients
82 period
83 pressure
84 prevalence
85 prognosis
86 ratio
87 relation
88 respect
89 retinopathy
90 scintigraphy
91 significant differences
92 significant statistical difference
93 statistical difference
94 study
95 sympathetic denervation
96 systolic blood pressure
97 terms
98 terms of age
99 use
100 schema:name Use of iodine-123 metaiodobenzylguanidine scintigraphy to assess cardiac sympathetic denervation and the impact of hypertension in patients with non-insulin-dependent diabetes mellitus
101 schema:pagination 1310-1316
102 schema:productId N12cd81a8c6a441f8b71699289282681d
103 N1c128848854d4b4db48805b14ce11b1b
104 N6bbe848ac81d44ed93bc31d901d1f760
105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040674720
106 https://doi.org/10.1007/s002590050588
107 schema:sdDatePublished 2021-12-01T19:13
108 schema:sdLicense https://scigraph.springernature.com/explorer/license/
109 schema:sdPublisher N09ee5142fe754491866e7f932b59bb20
110 schema:url https://doi.org/10.1007/s002590050588
111 sgo:license sg:explorer/license/
112 sgo:sdDataset articles
113 rdf:type schema:ScholarlyArticle
114 N09ee5142fe754491866e7f932b59bb20 schema:name Springer Nature - SN SciGraph project
115 rdf:type schema:Organization
116 N11fe3aa54bc94a0a9148549d9d59a526 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Radiopharmaceuticals
118 rdf:type schema:DefinedTerm
119 N12cd81a8c6a441f8b71699289282681d schema:name doi
120 schema:value 10.1007/s002590050588
121 rdf:type schema:PropertyValue
122 N1801620c8d6a433bbd28b2cf391b989f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Adult
124 rdf:type schema:DefinedTerm
125 N1b0d1849373749408a5e9909f78e4e93 schema:volumeNumber 26
126 rdf:type schema:PublicationVolume
127 N1c128848854d4b4db48805b14ce11b1b schema:name pubmed_id
128 schema:value 10541830
129 rdf:type schema:PropertyValue
130 N267743029cc748258834ec5bdf727190 rdf:first sg:person.01236544432.55
131 rdf:rest N6338e4285ccb4c56943ea4140d3e5ec2
132 N3bf279ce2eec49809c7597614860f51e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Humans
134 rdf:type schema:DefinedTerm
135 N51670ad1cd3f424ebba4ae54934d03c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Body Mass Index
137 rdf:type schema:DefinedTerm
138 N555461ef8d654b09b32e49d9525e1727 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Heart
140 rdf:type schema:DefinedTerm
141 N5d6e37338ebb46328483bfc5264cba16 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Hemoglobin A
143 rdf:type schema:DefinedTerm
144 N62900bc5b6a743fc85cc8fcc32a390ca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Prognosis
146 rdf:type schema:DefinedTerm
147 N6338e4285ccb4c56943ea4140d3e5ec2 rdf:first sg:person.01027604020.40
148 rdf:rest rdf:nil
149 N6927b93ac3d0491f840a29296dd7341f schema:issueNumber 10
150 rdf:type schema:PublicationIssue
151 N6bbe848ac81d44ed93bc31d901d1f760 schema:name dimensions_id
152 schema:value pub.1040674720
153 rdf:type schema:PropertyValue
154 N78ab61ed441f4507b7575ff50ce69ab0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Aged
156 rdf:type schema:DefinedTerm
157 N799abb5c5b7141e48c532d0785c2115e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Blood Pressure
159 rdf:type schema:DefinedTerm
160 N80a8429127744cb69612b630695b003c rdf:first sg:person.0714253726.86
161 rdf:rest N267743029cc748258834ec5bdf727190
162 N84174a358fb5416584573e89e9a570e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Follow-Up Studies
164 rdf:type schema:DefinedTerm
165 N875869f142234a9688104f2972b04d33 rdf:first sg:person.01006067432.06
166 rdf:rest N80a8429127744cb69612b630695b003c
167 N8cb859709f394b55b162e7f70a333ce9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Female
169 rdf:type schema:DefinedTerm
170 N8e77bf15026c431fb36fa9865470b62e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Hypertension
172 rdf:type schema:DefinedTerm
173 N98e36026a9644382ac2bae22c6e19d84 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Autonomic Nervous System Diseases
175 rdf:type schema:DefinedTerm
176 Na4d4857ffbc34edfbebe4d35c361321b rdf:first sg:person.01147716751.68
177 rdf:rest N875869f142234a9688104f2972b04d33
178 Nb3d9cdcdc90e43da8c72e535efd13e72 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Radionuclide Imaging
180 rdf:type schema:DefinedTerm
181 Nbafcfa53c482436da69cce02910f15c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Sympathetic Nervous System
183 rdf:type schema:DefinedTerm
184 Nce01cab07f8b4aabbb80c58a3f24ccde schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Aged, 80 and over
186 rdf:type schema:DefinedTerm
187 Nd5cf4d3fde724978bf13fa6442489128 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Male
189 rdf:type schema:DefinedTerm
190 Nd604bc4be0834e56aa9c4040256fea02 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name 3-Iodobenzylguanidine
192 rdf:type schema:DefinedTerm
193 Nde347e36df6c444090378ed64f3f5744 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Middle Aged
195 rdf:type schema:DefinedTerm
196 Ne2929b3facd546188dc6fedf47fab569 rdf:first sg:person.01016424677.17
197 rdf:rest Na4d4857ffbc34edfbebe4d35c361321b
198 Nf7ae94d909ad4c878c1c1414e7f00bac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Diabetes Mellitus, Type 2
200 rdf:type schema:DefinedTerm
201 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
202 schema:name Medical and Health Sciences
203 rdf:type schema:DefinedTerm
204 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
205 schema:name Cardiorespiratory Medicine and Haematology
206 rdf:type schema:DefinedTerm
207 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
208 schema:name Clinical Sciences
209 rdf:type schema:DefinedTerm
210 sg:journal.1297401 schema:issn 1619-7070
211 1619-7089
212 schema:name European Journal of Nuclear Medicine and Molecular Imaging
213 schema:publisher Springer Nature
214 rdf:type schema:Periodical
215 sg:person.01006067432.06 schema:affiliation grid-institutes:None
216 schema:familyName Nakatani
217 schema:givenName Yuko
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006067432.06
219 rdf:type schema:Person
220 sg:person.01016424677.17 schema:affiliation grid-institutes:None
221 schema:familyName Tamura
222 schema:givenName Koji
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016424677.17
224 rdf:type schema:Person
225 sg:person.01027604020.40 schema:affiliation grid-institutes:grid.410783.9
226 schema:familyName Iwasaka
227 schema:givenName Toshiji
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027604020.40
229 rdf:type schema:Person
230 sg:person.01147716751.68 schema:affiliation grid-institutes:None
231 schema:familyName Utsunomiya
232 schema:givenName Keita
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147716751.68
234 rdf:type schema:Person
235 sg:person.01236544432.55 schema:affiliation grid-institutes:None
236 schema:familyName Onishi
237 schema:givenName Satoshi
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236544432.55
239 rdf:type schema:Person
240 sg:person.0714253726.86 schema:affiliation grid-institutes:None
241 schema:familyName Saika
242 schema:givenName Yoshinori
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0714253726.86
244 rdf:type schema:Person
245 sg:pub.10.1007/bf00399929 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020782741
246 https://doi.org/10.1007/bf00399929
247 rdf:type schema:CreativeWork
248 sg:pub.10.1007/bf00401768 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029782596
249 https://doi.org/10.1007/bf00401768
250 rdf:type schema:CreativeWork
251 sg:pub.10.1007/bf00843703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026377699
252 https://doi.org/10.1007/bf00843703
253 rdf:type schema:CreativeWork
254 grid-institutes:None schema:alternateName Department of Internal Medicine, Keihanna Hospital, Hirakata City, Osaka, Japan, JP
255 Department of Radiology, Keihanna Hospital, Hirakata city, Japan, JP
256 schema:name Department of Internal Medicine, Keihanna Hospital, Hirakata City, Osaka, Japan, JP
257 Department of Radiology, Keihanna Hospital, Hirakata city, Japan, JP
258 rdf:type schema:Organization
259 grid-institutes:grid.410783.9 schema:alternateName Cardiovascular Center, Kansai Medical University, Osaka, Japan, JP
260 schema:name Cardiovascular Center, Kansai Medical University, Osaka, Japan, JP
261 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...