Ontology type: schema:ScholarlyArticle
2015-12-19
AUTHORSSophie Laffont, Yan Rolland, Valérie Ardisson, Julien Edeline, Marc Pracht, Samuel Le Sourd, Tanguy Rohou, Laurence Lenoir, Nicolas Lepareur, Etienne Garin
ABSTRACTPurposeRadioembolization of liver cancer with 90Y-loaded microspheres is increasingly used but data regarding hospital staff exposure are scarce. We evaluated the radiation exposure of medical staff while preparing and injecting 90Y-loaded glass and resin microspheres especially in view of the increasing use of these products.MethodsExposure of the chest and finger of the radiopharmacist, nuclear medicine physician and interventional radiologist during preparation and injection of 78 glass microsphere preparations and 16 resin microsphere preparations was monitored. Electronic dosimeters were used to measure chest exposure and ring dosimeters were used to measure finger exposure.ResultsChest exposure was very low for both products used (<10 μSv from preparation and injection). In our experience, finger exposure was significantly lower than the annual limit of 500 mSv for both products. With glass microspheres, the mean finger exposure was 13.7 ± 5.2 μSv/GBq for the radiopharmacist, and initially 17.9 ± 5.4 μSv/GBq for the nuclear medicine physician reducing to 13.97 ± 7.9 μSv/GBq with increasing experience. With resin microspheres, finger exposure was more significant: mean finger exposure for the radiopharmacist was 295.1 ± 271.9 μSv/GBq but with a reduction with increasing experience to 97.5 ± 35.2 μSv/GBq for the six most recent dose preparations. For administration of resin microspheres, the greatest mean finger exposure for the nuclear medicine physician (the most exposed operator) was 235.5 ± 156 μSv/GBq.ConclusionMedical staff performing 90Y-loaded microsphere radioembolization procedures are exposed to safe levels of radiation. Exposure is lower than that from treatments using 131I-lipiodol. The lowest finger exposure is from glass microspheres. With resin microspheres finger exposure is acceptable but could be optimized in accordance with the ALARA principle, and especially in view of the increasing use of radioembolization. More... »
PAGES824-831
http://scigraph.springernature.com/pub.10.1007/s00259-015-3277-1
DOIhttp://dx.doi.org/10.1007/s00259-015-3277-1
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1039917945
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/26686335
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