Significant clinical impact and prognostic stratification provided by FDG-PET in the staging of oesophageal cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-07

AUTHORS

Cuong P. Duong, Helen Demitriou, LeAnn Weih, Anne Thompson, David Williams, Robert J. S. Thomas, Rodney J. Hicks

ABSTRACT

PURPOSE: To evaluate the clinical impact of FDG-PET in staging oesophageal cancer and whether this information improves prognostic stratification. METHODS: Impact was based on comparison of a prospectively recorded pre-PET plan with post-PET treatment in 68 consecutive patients undergoing primary staging. Survival was analysed using the Kaplan-Meier product limit method and the Cox proportional hazards regression model. RESULTS: FDG-PET findings impacted on the management of 27/68 patients (40%): in 12 therapy was changed from curative to palliative and in three from palliative to curative, while in 12 other patients there was a change in the treatment modality or delivery but not in the treatment intent. The median survival was 21 months, with post-PET stage and treatment intent both strongly associated with survival (p<0.001). Conventional stage was not able to clearly stratify this population. CONCLUSION: The use of FDG-PET for primary staging of oesophageal cancer changed the clinical management of more than one-third of patients and provided superior prognostic stratification compared with conventional investigations. More... »

PAGES

759-769

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00259-005-0028-8

DOI

http://dx.doi.org/10.1007/s00259-005-0028-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050640083

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16470369


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00259-005-0028-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00259-005-0028-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00259-005-0028-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00259-005-0028-8'


 

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310 Division of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Vic., Australia
311 Statistical Center, Peter MacCallum Cancer Centre, Melbourne, Vic., Australia
312 rdf:type schema:Organization
 




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