MR imaging of clear cell sarcoma (malignant melanoma of the soft parts): a multicenter correlative MRI-pathology study of 21 cases ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2000-04

AUTHORS

L. H. De Beuckeleer, A. M. De Schepper, J. E. Vandevenne, J. L. Bloem, A. M. Davies, M. Oudkerk, E. Hauben, E. Van Marck, J. Somville, D. Vanel, L. S. Steinbach, J. M. Guinebretière, P. C. W. Hogendoorn, W. J. Mooi, K. Verstraete, C. Zaloudek, H. Jones

ABSTRACT

OBJECTIVE: To evaluate MR imaging and pathology findings in order to define the characteristic features of clear cell sarcoma of the soft tissues (malignant melanoma of the soft parts). DESIGN AND PATIENTS: MR examinations of 21 patients with histologically proven clear cell sarcoma of the musculoskeletal system were retrospectively reviewed and assessed for shape, homogeneity, delineation, signal intensities on T1- and T2-weighted images, contrast enhancement, relationship with adjacent fascia or tendon, secondary bone involvement, and intratumoral necrosis. In 19 cases the pathology findings were available for review and for a comparative MR-pathology study. RESULTS: On T1-weighted images, lesions were isointense (n=3), hypointense (n=7) or slightly hyperintense to muscle (n=11). Immunohistochemical examination was performed in 17 patients. All 17 specimens showed positivity for HMB-45 antibody. In nine of 11 lesions with slightly increased signal intensity on T1-weighted images, a correlative MR imaging-pathology study was possible. All nine were positive to HMB-45 antibody. CONCLUSIONS: Clear cell sarcoma of the musculoskeletal system often has a benign-looking appearance on MR images. In up to 52% of patients, this lesion with melanocytic differentiation has slightly increased signal intensity on T1-weighted images compared with muscle. As the presence of this relative higher signal intensity on T1-weighted images is rather specific for tumors displaying melanocytic differentiation, radiologists should familiarize themselves with this rare entity and include it in their differential diagnosis when confronted with a well-defined, homogeneous, strongly enhancing mass with slightly higher signal intensity compared with muscle on native T1-weighted images. More... »

PAGES

187-195

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s002560050592

DOI

http://dx.doi.org/10.1007/s002560050592

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010813490

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10855466


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diagnosis, Differential", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sarcoma, Clear Cell", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Soft Tissue Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Antwerp University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411414.5", 
          "name": [
            "Department of Radiology, University Hospital Antwerp (University of Antwerp), Wilrijkstraat 10, 2650 Edegem, Belgium, BE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "De Beuckeleer", 
        "givenName": "L. H.", 
        "id": "sg:person.01164750624.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01164750624.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Antwerp University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411414.5", 
          "name": [
            "Department of Radiology, University Hospital Antwerp (University of Antwerp), Wilrijkstraat 10, 2650 Edegem, Belgium, BE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "De Schepper", 
        "givenName": "A. M.", 
        "id": "sg:person.01037637671.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01037637671.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Antwerp University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411414.5", 
          "name": [
            "Department of Radiology, University Hospital Antwerp (University of Antwerp), Wilrijkstraat 10, 2650 Edegem, Belgium, BE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vandevenne", 
        "givenName": "J. E.", 
        "id": "sg:person.01104252043.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104252043.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leiden University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.10419.3d", 
          "name": [
            "Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands, NL"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bloem", 
        "givenName": "J. L.", 
        "id": "sg:person.0632157120.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632157120.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Orthopaedic Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416189.3", 
          "name": [
            "MRI Center, Royal Orthopaedic Hospital, Birmingham, UK, GB"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Davies", 
        "givenName": "A. M.", 
        "id": "sg:person.01044676202.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044676202.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Erasmus University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.5645.2", 
          "name": [
            "Department of Radiology, Daniel Den Hoed Kliniek (Academisch Ziekenhuis Rotterdam), Rotterdam, The Netherlands, NL"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oudkerk", 
        "givenName": "M.", 
        "id": "sg:person.01313240412.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313240412.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Antwerp University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411414.5", 
          "name": [
            "Department of Pathology, University Hospital Antwerp (University of Antwerp), Edegem, Belgium, BE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hauben", 
        "givenName": "E.", 
        "id": "sg:person.0775060525.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775060525.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Antwerp University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411414.5", 
          "name": [
            "Department of Pathology, University Hospital Antwerp (University of Antwerp), Edegem, Belgium, BE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Van Marck", 
        "givenName": "E.", 
        "id": "sg:person.0613633757.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613633757.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Antwerp University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411414.5", 
          "name": [
            "Department of Orthopaedic Surgery, University Hospital Antwerp (University of Antwerp), Edegem, Belgium, BE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Somville", 
        "givenName": "J.", 
        "id": "sg:person.01163563734.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163563734.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Department of Radiology, Institut Gustave-Roussy, Villejuif, France, FR"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vanel", 
        "givenName": "D.", 
        "id": "sg:person.01036545346.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036545346.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Francisco", 
          "id": "https://www.grid.ac/institutes/grid.266102.1", 
          "name": [
            "Department of Radiology, University of California San Francisco (UCSF), San Francisco, California, USA, US"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Steinbach", 
        "givenName": "L. S.", 
        "id": "sg:person.01212433144.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212433144.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Department of Pathology, Institut Gustave-Roussy, Villejuif, France, FR"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guinebreti\u00e8re", 
        "givenName": "J. M.", 
        "id": "sg:person.01244162220.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244162220.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leiden University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.10419.3d", 
          "name": [
            "Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands, NL"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hogendoorn", 
        "givenName": "P. C. W.", 
        "id": "sg:person.0577703344.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577703344.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Erasmus University Rotterdam", 
          "id": "https://www.grid.ac/institutes/grid.6906.9", 
          "name": [
            "Institute of Pathology, Erasmus University Rotterdam, Rotterdam, The Netherlands, NL"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mooi", 
        "givenName": "W. J.", 
        "id": "sg:person.01005402025.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005402025.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ghent University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410566.0", 
          "name": [
            "Department of Radiology, University Hospital Ghent, Ghent, Belgium, BE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Verstraete", 
        "givenName": "K.", 
        "id": "sg:person.0576505517.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576505517.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Francisco", 
          "id": "https://www.grid.ac/institutes/grid.266102.1", 
          "name": [
            "Department of Pathology, University of California San Francisco (UCSF), San Francisco, California, USA, US"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zaloudek", 
        "givenName": "C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stanford University", 
          "id": "https://www.grid.ac/institutes/grid.168010.e", 
          "name": [
            "Department of Radiology, Stanford University, Stanford, California, USA, US"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jones", 
        "givenName": "H.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00361477", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002902021", 
          "https://doi.org/10.1007/bf00361477"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-662-07859-4_20", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004584324", 
          "https://doi.org/10.1007/978-3-662-07859-4_20"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-4608(92)90012-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006057239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-198307000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006902424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-198307000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006902424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-198307000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006902424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bjo.77.5.297", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021311958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s003300050534", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022186339", 
          "https://doi.org/10.1007/s003300050534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2133.1996.d01-1012.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023451600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002560050063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027489836", 
          "https://doi.org/10.1007/s002560050063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2559.1995.tb00292.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033508428"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2559.1995.tb00292.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033508428"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2559.1993.tb00499.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037923526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199212000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043977166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199212000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043977166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00198412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048622119", 
          "https://doi.org/10.1007/bf00198412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00198412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048622119", 
          "https://doi.org/10.1007/bf00198412"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2000-04", 
    "datePublishedReg": "2000-04-01", 
    "description": "OBJECTIVE: To evaluate MR imaging and pathology findings in order to define the characteristic features of clear cell sarcoma of the soft tissues (malignant melanoma of the soft parts).\nDESIGN AND PATIENTS: MR examinations of 21 patients with histologically proven clear cell sarcoma of the musculoskeletal system were retrospectively reviewed and assessed for shape, homogeneity, delineation, signal intensities on T1- and T2-weighted images, contrast enhancement, relationship with adjacent fascia or tendon, secondary bone involvement, and intratumoral necrosis. In 19 cases the pathology findings were available for review and for a comparative MR-pathology study.\nRESULTS: On T1-weighted images, lesions were isointense (n=3), hypointense (n=7) or slightly hyperintense to muscle (n=11). Immunohistochemical examination was performed in 17 patients. All 17 specimens showed positivity for HMB-45 antibody. In nine of 11 lesions with slightly increased signal intensity on T1-weighted images, a correlative MR imaging-pathology study was possible. All nine were positive to HMB-45 antibody.\nCONCLUSIONS: Clear cell sarcoma of the musculoskeletal system often has a benign-looking appearance on MR images. In up to 52% of patients, this lesion with melanocytic differentiation has slightly increased signal intensity on T1-weighted images compared with muscle. As the presence of this relative higher signal intensity on T1-weighted images is rather specific for tumors displaying melanocytic differentiation, radiologists should familiarize themselves with this rare entity and include it in their differential diagnosis when confronted with a well-defined, homogeneous, strongly enhancing mass with slightly higher signal intensity compared with muscle on native T1-weighted images.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s002560050592", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1086201", 
        "issn": [
          "0364-2348", 
          "1432-2161"
        ], 
        "name": "Skeletal Radiology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "29"
      }
    ], 
    "name": "MR imaging of clear cell sarcoma (malignant melanoma of the soft parts): a multicenter correlative MRI-pathology study of 21 cases and literature review", 
    "pagination": "187-195", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "33844fde861549ac859a6a9172f75c1521568e39e73ef0270628c36ffb6f6cfe"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10855466"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7701953"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s002560050592"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1010813490"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s002560050592", 
      "https://app.dimensions.ai/details/publication/pub.1010813490"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:42", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000511.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs002560050592"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s002560050592'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s002560050592'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s002560050592'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s002560050592'


 

This table displays all metadata directly associated to this object as RDF triples.

301 TRIPLES      21 PREDICATES      54 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s002560050592 schema:about N08f14525a2574bba9f7a1bd6f29a2e90
2 N472a786dd1564f27bc6f088f646979d7
3 N497448a64aae4c7b98a7497964c728c1
4 N4ef67e8a77c3410da9ad44c2483a2995
5 N5102dc1758ef4a269dd814fa4c8d0cf4
6 N60fdecb02feb4ee38c782143460fa5a7
7 N7898934b4f0042e896e0d895a00c6863
8 N7c10db6891664d27a44cbbef8904bd18
9 N82c1f0c779734c7d93416809ddd5fd89
10 N872c9d0c9108450b88b485ec5e44a692
11 Na79428c3e2254c6a9bd4085d69a5c295
12 Nc5f87a09c8d94b708cf66675f101e804
13 Nf5012eca08fb4af2b47aafc6523e47fb
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author Nb4170b94f5b04b42b81324733b0334d1
17 schema:citation sg:pub.10.1007/978-3-662-07859-4_20
18 sg:pub.10.1007/bf00198412
19 sg:pub.10.1007/bf00361477
20 sg:pub.10.1007/s002560050063
21 sg:pub.10.1007/s003300050534
22 https://doi.org/10.1016/0165-4608(92)90012-w
23 https://doi.org/10.1046/j.1365-2133.1996.d01-1012.x
24 https://doi.org/10.1097/00000478-198307000-00003
25 https://doi.org/10.1097/00000478-199212000-00006
26 https://doi.org/10.1111/j.1365-2559.1993.tb00499.x
27 https://doi.org/10.1111/j.1365-2559.1995.tb00292.x
28 https://doi.org/10.1136/bjo.77.5.297
29 schema:datePublished 2000-04
30 schema:datePublishedReg 2000-04-01
31 schema:description OBJECTIVE: To evaluate MR imaging and pathology findings in order to define the characteristic features of clear cell sarcoma of the soft tissues (malignant melanoma of the soft parts). DESIGN AND PATIENTS: MR examinations of 21 patients with histologically proven clear cell sarcoma of the musculoskeletal system were retrospectively reviewed and assessed for shape, homogeneity, delineation, signal intensities on T1- and T2-weighted images, contrast enhancement, relationship with adjacent fascia or tendon, secondary bone involvement, and intratumoral necrosis. In 19 cases the pathology findings were available for review and for a comparative MR-pathology study. RESULTS: On T1-weighted images, lesions were isointense (n=3), hypointense (n=7) or slightly hyperintense to muscle (n=11). Immunohistochemical examination was performed in 17 patients. All 17 specimens showed positivity for HMB-45 antibody. In nine of 11 lesions with slightly increased signal intensity on T1-weighted images, a correlative MR imaging-pathology study was possible. All nine were positive to HMB-45 antibody. CONCLUSIONS: Clear cell sarcoma of the musculoskeletal system often has a benign-looking appearance on MR images. In up to 52% of patients, this lesion with melanocytic differentiation has slightly increased signal intensity on T1-weighted images compared with muscle. As the presence of this relative higher signal intensity on T1-weighted images is rather specific for tumors displaying melanocytic differentiation, radiologists should familiarize themselves with this rare entity and include it in their differential diagnosis when confronted with a well-defined, homogeneous, strongly enhancing mass with slightly higher signal intensity compared with muscle on native T1-weighted images.
32 schema:genre research_article
33 schema:inLanguage en
34 schema:isAccessibleForFree true
35 schema:isPartOf Nb12f72f6710244edae845517c681ed82
36 Nfd7fb5943f6b471a906d447d316b6995
37 sg:journal.1086201
38 schema:name MR imaging of clear cell sarcoma (malignant melanoma of the soft parts): a multicenter correlative MRI-pathology study of 21 cases and literature review
39 schema:pagination 187-195
40 schema:productId N66e1165b017a4f48936678125f9a9cc8
41 N9400213e108a4224813e1e61d163d6c3
42 N9b3b34b041ef4e9cb83acd57368abf64
43 Nf17ac3215bdf42d985a97d93910eccca
44 Nf5ebd2b2073444e2bb8066c274ed794f
45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010813490
46 https://doi.org/10.1007/s002560050592
47 schema:sdDatePublished 2019-04-10T16:42
48 schema:sdLicense https://scigraph.springernature.com/explorer/license/
49 schema:sdPublisher N40cadab7856e4cdb9b750a42de0f64cd
50 schema:url http://link.springer.com/10.1007%2Fs002560050592
51 sgo:license sg:explorer/license/
52 sgo:sdDataset articles
53 rdf:type schema:ScholarlyArticle
54 N08f14525a2574bba9f7a1bd6f29a2e90 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
55 schema:name Aged
56 rdf:type schema:DefinedTerm
57 N0f6965c7cfd34607befa673776f8bd30 rdf:first sg:person.01244162220.06
58 rdf:rest Nb6631695d0144cac8ad65850e4d5a262
59 N3917e9ad52d64ef0b2dd0d09b82d39b4 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
60 schema:familyName Jones
61 schema:givenName H.
62 rdf:type schema:Person
63 N40cadab7856e4cdb9b750a42de0f64cd schema:name Springer Nature - SN SciGraph project
64 rdf:type schema:Organization
65 N472a786dd1564f27bc6f088f646979d7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
66 schema:name Middle Aged
67 rdf:type schema:DefinedTerm
68 N497448a64aae4c7b98a7497964c728c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Humans
70 rdf:type schema:DefinedTerm
71 N49884ba831f0442c9d03fd3d5976b4f4 rdf:first sg:person.0775060525.36
72 rdf:rest Nae6422699ece409b96e26e152e8449e2
73 N4d234202a4864acf8ab455a2c9b19920 rdf:first sg:person.01044676202.23
74 rdf:rest Ndd82a0f682544a0d822b18709909d41f
75 N4ef67e8a77c3410da9ad44c2483a2995 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Retrospective Studies
77 rdf:type schema:DefinedTerm
78 N5102dc1758ef4a269dd814fa4c8d0cf4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Sarcoma, Clear Cell
80 rdf:type schema:DefinedTerm
81 N5d1143c4cdff45d1ac78ed2f9f2d7a96 rdf:first sg:person.01005402025.94
82 rdf:rest Ndd4c60eeea6c49049321148a368b7707
83 N60fdecb02feb4ee38c782143460fa5a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Adolescent
85 rdf:type schema:DefinedTerm
86 N66e1165b017a4f48936678125f9a9cc8 schema:name nlm_unique_id
87 schema:value 7701953
88 rdf:type schema:PropertyValue
89 N7898934b4f0042e896e0d895a00c6863 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Soft Tissue Neoplasms
91 rdf:type schema:DefinedTerm
92 N7c10db6891664d27a44cbbef8904bd18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Magnetic Resonance Imaging
94 rdf:type schema:DefinedTerm
95 N81779b8c26eb4e20b6623207b3a3afd8 rdf:first N3917e9ad52d64ef0b2dd0d09b82d39b4
96 rdf:rest rdf:nil
97 N82c1f0c779734c7d93416809ddd5fd89 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Immunohistochemistry
99 rdf:type schema:DefinedTerm
100 N872c9d0c9108450b88b485ec5e44a692 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Diagnosis, Differential
102 rdf:type schema:DefinedTerm
103 N9400213e108a4224813e1e61d163d6c3 schema:name pubmed_id
104 schema:value 10855466
105 rdf:type schema:PropertyValue
106 N9b3b34b041ef4e9cb83acd57368abf64 schema:name readcube_id
107 schema:value 33844fde861549ac859a6a9172f75c1521568e39e73ef0270628c36ffb6f6cfe
108 rdf:type schema:PropertyValue
109 Na0a2b6612687421eb8e5a47f8b994123 rdf:first sg:person.01163563734.69
110 rdf:rest Nd423ec03d0c145ae89035a64ee56a15a
111 Na79428c3e2254c6a9bd4085d69a5c295 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Adult
113 rdf:type schema:DefinedTerm
114 Nae6422699ece409b96e26e152e8449e2 rdf:first sg:person.0613633757.65
115 rdf:rest Na0a2b6612687421eb8e5a47f8b994123
116 Naf8cb77b077946eaa0af52cd6b2ef3d8 rdf:first sg:person.0632157120.50
117 rdf:rest N4d234202a4864acf8ab455a2c9b19920
118 Nb12f72f6710244edae845517c681ed82 schema:volumeNumber 29
119 rdf:type schema:PublicationVolume
120 Nb215837b1a6f42509ea5613121e63f25 rdf:first sg:person.01037637671.32
121 rdf:rest Ne0469ce58a8343d6947c75c3d67dce6f
122 Nb25ec69ff60f40bbb1d245dab837f828 rdf:first sg:person.01212433144.08
123 rdf:rest N0f6965c7cfd34607befa673776f8bd30
124 Nb4170b94f5b04b42b81324733b0334d1 rdf:first sg:person.01164750624.48
125 rdf:rest Nb215837b1a6f42509ea5613121e63f25
126 Nb6631695d0144cac8ad65850e4d5a262 rdf:first sg:person.0577703344.59
127 rdf:rest N5d1143c4cdff45d1ac78ed2f9f2d7a96
128 Nb822d7840035427f81b48baf971275ec schema:affiliation https://www.grid.ac/institutes/grid.266102.1
129 schema:familyName Zaloudek
130 schema:givenName C.
131 rdf:type schema:Person
132 Nc5f87a09c8d94b708cf66675f101e804 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Male
134 rdf:type schema:DefinedTerm
135 Nd423ec03d0c145ae89035a64ee56a15a rdf:first sg:person.01036545346.36
136 rdf:rest Nb25ec69ff60f40bbb1d245dab837f828
137 Ndd4c60eeea6c49049321148a368b7707 rdf:first sg:person.0576505517.03
138 rdf:rest Nea1589fe2d0d420b979146b467628dc5
139 Ndd82a0f682544a0d822b18709909d41f rdf:first sg:person.01313240412.78
140 rdf:rest N49884ba831f0442c9d03fd3d5976b4f4
141 Ne0469ce58a8343d6947c75c3d67dce6f rdf:first sg:person.01104252043.75
142 rdf:rest Naf8cb77b077946eaa0af52cd6b2ef3d8
143 Nea1589fe2d0d420b979146b467628dc5 rdf:first Nb822d7840035427f81b48baf971275ec
144 rdf:rest N81779b8c26eb4e20b6623207b3a3afd8
145 Nf17ac3215bdf42d985a97d93910eccca schema:name doi
146 schema:value 10.1007/s002560050592
147 rdf:type schema:PropertyValue
148 Nf5012eca08fb4af2b47aafc6523e47fb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Female
150 rdf:type schema:DefinedTerm
151 Nf5ebd2b2073444e2bb8066c274ed794f schema:name dimensions_id
152 schema:value pub.1010813490
153 rdf:type schema:PropertyValue
154 Nfd7fb5943f6b471a906d447d316b6995 schema:issueNumber 4
155 rdf:type schema:PublicationIssue
156 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
157 schema:name Medical and Health Sciences
158 rdf:type schema:DefinedTerm
159 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
160 schema:name Clinical Sciences
161 rdf:type schema:DefinedTerm
162 sg:journal.1086201 schema:issn 0364-2348
163 1432-2161
164 schema:name Skeletal Radiology
165 rdf:type schema:Periodical
166 sg:person.01005402025.94 schema:affiliation https://www.grid.ac/institutes/grid.6906.9
167 schema:familyName Mooi
168 schema:givenName W. J.
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005402025.94
170 rdf:type schema:Person
171 sg:person.01036545346.36 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
172 schema:familyName Vanel
173 schema:givenName D.
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036545346.36
175 rdf:type schema:Person
176 sg:person.01037637671.32 schema:affiliation https://www.grid.ac/institutes/grid.411414.5
177 schema:familyName De Schepper
178 schema:givenName A. M.
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01037637671.32
180 rdf:type schema:Person
181 sg:person.01044676202.23 schema:affiliation https://www.grid.ac/institutes/grid.416189.3
182 schema:familyName Davies
183 schema:givenName A. M.
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044676202.23
185 rdf:type schema:Person
186 sg:person.01104252043.75 schema:affiliation https://www.grid.ac/institutes/grid.411414.5
187 schema:familyName Vandevenne
188 schema:givenName J. E.
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104252043.75
190 rdf:type schema:Person
191 sg:person.01163563734.69 schema:affiliation https://www.grid.ac/institutes/grid.411414.5
192 schema:familyName Somville
193 schema:givenName J.
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163563734.69
195 rdf:type schema:Person
196 sg:person.01164750624.48 schema:affiliation https://www.grid.ac/institutes/grid.411414.5
197 schema:familyName De Beuckeleer
198 schema:givenName L. H.
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01164750624.48
200 rdf:type schema:Person
201 sg:person.01212433144.08 schema:affiliation https://www.grid.ac/institutes/grid.266102.1
202 schema:familyName Steinbach
203 schema:givenName L. S.
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212433144.08
205 rdf:type schema:Person
206 sg:person.01244162220.06 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
207 schema:familyName Guinebretière
208 schema:givenName J. M.
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244162220.06
210 rdf:type schema:Person
211 sg:person.01313240412.78 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
212 schema:familyName Oudkerk
213 schema:givenName M.
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313240412.78
215 rdf:type schema:Person
216 sg:person.0576505517.03 schema:affiliation https://www.grid.ac/institutes/grid.410566.0
217 schema:familyName Verstraete
218 schema:givenName K.
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576505517.03
220 rdf:type schema:Person
221 sg:person.0577703344.59 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
222 schema:familyName Hogendoorn
223 schema:givenName P. C. W.
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577703344.59
225 rdf:type schema:Person
226 sg:person.0613633757.65 schema:affiliation https://www.grid.ac/institutes/grid.411414.5
227 schema:familyName Van Marck
228 schema:givenName E.
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613633757.65
230 rdf:type schema:Person
231 sg:person.0632157120.50 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
232 schema:familyName Bloem
233 schema:givenName J. L.
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632157120.50
235 rdf:type schema:Person
236 sg:person.0775060525.36 schema:affiliation https://www.grid.ac/institutes/grid.411414.5
237 schema:familyName Hauben
238 schema:givenName E.
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775060525.36
240 rdf:type schema:Person
241 sg:pub.10.1007/978-3-662-07859-4_20 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004584324
242 https://doi.org/10.1007/978-3-662-07859-4_20
243 rdf:type schema:CreativeWork
244 sg:pub.10.1007/bf00198412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048622119
245 https://doi.org/10.1007/bf00198412
246 rdf:type schema:CreativeWork
247 sg:pub.10.1007/bf00361477 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002902021
248 https://doi.org/10.1007/bf00361477
249 rdf:type schema:CreativeWork
250 sg:pub.10.1007/s002560050063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027489836
251 https://doi.org/10.1007/s002560050063
252 rdf:type schema:CreativeWork
253 sg:pub.10.1007/s003300050534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022186339
254 https://doi.org/10.1007/s003300050534
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1016/0165-4608(92)90012-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1006057239
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1046/j.1365-2133.1996.d01-1012.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1023451600
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1097/00000478-198307000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006902424
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1097/00000478-199212000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043977166
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1111/j.1365-2559.1993.tb00499.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037923526
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1111/j.1365-2559.1995.tb00292.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033508428
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1136/bjo.77.5.297 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021311958
269 rdf:type schema:CreativeWork
270 https://www.grid.ac/institutes/grid.10419.3d schema:alternateName Leiden University Medical Center
271 schema:name Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands, NL
272 Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands, NL
273 rdf:type schema:Organization
274 https://www.grid.ac/institutes/grid.14925.3b schema:alternateName Institut Gustave Roussy
275 schema:name Department of Pathology, Institut Gustave-Roussy, Villejuif, France, FR
276 Department of Radiology, Institut Gustave-Roussy, Villejuif, France, FR
277 rdf:type schema:Organization
278 https://www.grid.ac/institutes/grid.168010.e schema:alternateName Stanford University
279 schema:name Department of Radiology, Stanford University, Stanford, California, USA, US
280 rdf:type schema:Organization
281 https://www.grid.ac/institutes/grid.266102.1 schema:alternateName University of California, San Francisco
282 schema:name Department of Pathology, University of California San Francisco (UCSF), San Francisco, California, USA, US
283 Department of Radiology, University of California San Francisco (UCSF), San Francisco, California, USA, US
284 rdf:type schema:Organization
285 https://www.grid.ac/institutes/grid.410566.0 schema:alternateName Ghent University Hospital
286 schema:name Department of Radiology, University Hospital Ghent, Ghent, Belgium, BE
287 rdf:type schema:Organization
288 https://www.grid.ac/institutes/grid.411414.5 schema:alternateName Antwerp University Hospital
289 schema:name Department of Orthopaedic Surgery, University Hospital Antwerp (University of Antwerp), Edegem, Belgium, BE
290 Department of Pathology, University Hospital Antwerp (University of Antwerp), Edegem, Belgium, BE
291 Department of Radiology, University Hospital Antwerp (University of Antwerp), Wilrijkstraat 10, 2650 Edegem, Belgium, BE
292 rdf:type schema:Organization
293 https://www.grid.ac/institutes/grid.416189.3 schema:alternateName Royal Orthopaedic Hospital
294 schema:name MRI Center, Royal Orthopaedic Hospital, Birmingham, UK, GB
295 rdf:type schema:Organization
296 https://www.grid.ac/institutes/grid.5645.2 schema:alternateName Erasmus University Medical Center
297 schema:name Department of Radiology, Daniel Den Hoed Kliniek (Academisch Ziekenhuis Rotterdam), Rotterdam, The Netherlands, NL
298 rdf:type schema:Organization
299 https://www.grid.ac/institutes/grid.6906.9 schema:alternateName Erasmus University Rotterdam
300 schema:name Institute of Pathology, Erasmus University Rotterdam, Rotterdam, The Netherlands, NL
301 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...