CT-guided corticosteroid injection for solitary eosinophilic granuloma of the spine View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-10-08

AUTHORS

Eugenio Rimondi, Andreas F. Mavrogenis, Giuseppe Rossi, Giuseppe Ussia, Andrea Angelini, Pietro Ruggieri

ABSTRACT

ObjectiveTo evaluate the clinical and imaging outcome of patients with symptomatic eosinophilic granuloma of the spine treated with CT-guided intralesional methylprednisolone injection after biopsy.Materials and methodsPatients (n =19) with symptomatic solitary eosinophilic granuloma of the spine treated by CT-guided intralesional methylprednisolone injection were retrospectively studied. There were 12 males and seven females with a mean age of 17 years (range, 3–43 years). The mean follow-up was 6 years (median, 4 years; range, 0.5–19 years). Spinal location included the cervical (two patients), thoracic (seven patients), lumbar spine (eight patients), and the sacrum (two patients). Vertebra plana was observed in two patients. All patients had biopsies before treatment.ResultsComplete resolution of pain and healing of the lesion was observed in 17 patients (89.5%); none of these patients had recurrence at the latest examination. Reconstitution of the T1 and L1 vertebra plana was observed in both patients. Two patients initially diagnosed and treated for a solitary eosinophilic granuloma had constant pain after the procedure; in these patients, 6 and 12 months after the procedure, respectively, imaging showed multifocal disease and systemic therapy was administered. Complications related to the procedure were not observed. General anesthesia was administered in two patients because of intolerable pain during the procedure.ConclusionsIn view of the benign clinical course of eosinophilic granuloma, in patients with symptomatic lesions, CT-guided intralesional corticosteroid injection is a safe and effective outpatient treatment with a low complication rate. More... »

PAGES

757-764

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00256-010-1045-7

DOI

http://dx.doi.org/10.1007/s00256-010-1045-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044361404

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20931189


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