Osteosarcoma associated with hyperparathyroidism View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-05-25

AUTHORS

Paul C. Jutte, Renato Rosso, Massimiliano de Paolis, Costatino Errani, Elisabetta Pasini, Laura Campanacci, Gaetano Bacci, Franco Bertoni, Mario Mercuri

ABSTRACT

The fourth case in the literature is presented of a patient with the rare association of hyperparathyroidism and osteosarcoma. A 56-year-old woman presented with hyperparathyroidism and a lesion in the tibia. Initial diagnosis was brown tumor. Histology, however, revealed osteosarcoma, and the patient was treated accordingly. The experimental induction of osteosarcoma by parathormone in rodent studies makes this finding alarming, considering the increasing use of parathormone in the treatment of osteoporosis. The mechanism by which osteosarcoma is induced in humans cannot be explained based on current knowledge of mechanisms of action of parathyroid hormone. More... »

PAGES

473-476

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00256-004-0771-0

DOI

http://dx.doi.org/10.1007/s00256-004-0771-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018540296

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15160256


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192 rdf:type schema:Organization
193 grid-institutes:grid.8982.b schema:alternateName Anatomia Patologica Università di Pavia, via Forlanini 16, 27100, Pavia, Italy
194 schema:name Anatomia Patologica Università di Pavia, via Forlanini 16, 27100, Pavia, Italy
195 rdf:type schema:Organization
 




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