The use of micro-organisms for L-ascorbic acid production: current status and future perspectives View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-09

AUTHORS

R. Hancock, R. Viola

ABSTRACT

L-Ascorbic acid (L-AA) has been industrially produced for around 60 years in a primarily chemical process utilising D-glucose (D-glc) as starting material. Current world production is estimated at approximately 80,000 tonnes per annum with a worldwide market in excess of U.S. $600 million. We present a brief overview of research geared to exploiting micro-organisms for the industrial production of vitamin C, with emphasis on recent approaches using genetically engineered bacterial strains. We also discuss the potential for direct production of L-AA exploiting novel biochemical pathways with particular reference to yeast fermentations. The potential advantages of these novel approaches over current chemical and biotechnological processes are outlined. More... »

PAGES

567-576

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s002530100723

DOI

http://dx.doi.org/10.1007/s002530100723

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040953250

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11601603


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