Biotechnological production of itaconic acid View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-08

AUTHORS

Th. Willke, K.-D. Vorlop

ABSTRACT

Itaconic acid (IA) is an unsaturated dicarbonic organic acid. It can easily be incorporated into polymers and may serve as a substitute for petrochemical-based acrylic or methacrylic acid. It is used at 1-5% as a co-monomer in resins and also in the manufacture of synthetic fibres, in coatings, adhesives, thickeners and binders. The favoured production process is fermentation of carbohydrates by fungi, with a current market volume of about 15,000 t/a. Due to the high price of about US$ 4/kg, the use of IA is restricted. At present, the production rates do not exceed 1 g l(-1) h(-1), accompanied by product concentrations of about 80 g l(-1). New biotechnology approaches, such as immobilisation techniques, screening programmes and genetic engineering, could lead to higher productivity. Also, the use of alternative substrates may reduce costs and thus open the market for new and increased applications. More... »

PAGES

289-295

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s002530100685

DOI

http://dx.doi.org/10.1007/s002530100685

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023793698

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11548996


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