Remarkable diversification of bacterial azoreductases: primary sequences, structures, substrates, physiological roles, and biotechnological applications View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-03

AUTHORS

Hirokazu Suzuki

ABSTRACT

Azoreductases reductively cleave azo linkages by using NAD(P)H as an electron donor. The enzymes are widely found in bacteria and act on numerous azo dyes, which allow various unique applications. This review describes primary amino acid sequences, structures, substrates, physiological roles, and biotechnological applications of bacterial azoreductases to discuss their remarkable diversification. According to primary sequences, azoreductases were classified phylogenetically into four main clades. Most members of clades I-III are flavoproteins, whereas clade IV members include flavin-free azoreductases. Clades I and II prefer NADPH and NADH, respectively, as electron donors, whereas other members generally use both. Several enzymes formed no clades; moreover, some bacteria produce azoreductases with longer primary structures than those hitherto identified, which implies further diversification of bacterial azoreductases. The crystal structures commonly reveal the Rossmann folds; however, ternary structures are moderately varied with different quaternary conformation. Although physiological roles are obscure, several azoreductases have been shown to act on metabolites such as flavins, quinones, and metal ions more efficiently than on azo dyes. Considering that many homologs exclusively act on these metabolites, it is possible that azoreductases are actually side activities of versatile reductases that act on various substrates with different specificities. In parallel, this idea raises the possibility that homologous enzymes, even if these are already defined as other types of reductases, widely harbor azoreductase activities. Although azoreductases for which their genes have been identified are not abundant, it may be simple to identify azoreductases of biotechnological importance that have novel substrate specificities. More... »

PAGES

1-14

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00253-019-09775-2

DOI

http://dx.doi.org/10.1007/s00253-019-09775-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113179814

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30941462


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Tottori University", 
          "id": "https://www.grid.ac/institutes/grid.265107.7", 
          "name": [
            "Faculty of Engineering, Tottori University, 4-101 Koyama-Minami, 680-8552, Tottori, Japan", 
            "Center for Research on Green Sustainable Chemistry, Tottori University, 4-101 Koyama-Minami, 680-8552, Tottori, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suzuki", 
        "givenName": "Hirokazu", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1271/bbb.110397", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002348122"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.anaerobe.2011.12.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002673741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10529-013-1338-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002710013", 
          "https://doi.org/10.1007/s10529-013-1338-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-009-2351-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003156970", 
          "https://doi.org/10.1007/s00253-009-2351-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-009-2351-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003156970", 
          "https://doi.org/10.1007/s00253-009-2351-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-009-2351-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003156970", 
          "https://doi.org/10.1007/s00253-009-2351-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s1744309109044741", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003707387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s1744309109044741", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003707387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1110/ps.073029607", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004120803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/mcp.m500394-mcp200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004263446"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biortech.2013.09.124", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004732136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2091-11-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007202118", 
          "https://doi.org/10.1186/1471-2091-11-13"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m710070200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007412399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.addr.2004.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007961659"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-007-1212-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010809249", 
          "https://doi.org/10.1007/s00253-007-1212-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-007-1212-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010809249", 
          "https://doi.org/10.1007/s00253-007-1212-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-014-5896-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013552693", 
          "https://doi.org/10.1007/s00253-014-5896-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/bph.13571", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013570100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6976.2008.00107.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014835876"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmcl.2011.09.071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015281843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijpharm.2008.09.058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015877692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-009-1911-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015970605", 
          "https://doi.org/10.1007/s00253-009-1911-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-009-1911-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015970605", 
          "https://doi.org/10.1007/s00253-009-1911-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11274-012-1198-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016227358", 
          "https://doi.org/10.1007/s11274-012-1198-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcatb.2016.04.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016484839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m002617200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016518933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/dddt.s48636", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017008022"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-007-1087-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017167527", 
          "https://doi.org/10.1007/s00253-007-1087-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-007-1087-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017167527", 
          "https://doi.org/10.1007/s00253-007-1087-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s1399004713030988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019675446"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0098551", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020002736"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10930-013-9522-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020271951", 
          "https://doi.org/10.1007/s10930-013-9522-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13238-010-0090-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021614383", 
          "https://doi.org/10.1007/s13238-010-0090-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13238-010-0090-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021614383", 
          "https://doi.org/10.1007/s13238-010-0090-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10529-007-9627-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023103702", 
          "https://doi.org/10.1007/s10529-007-9627-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10529-007-9627-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023103702", 
          "https://doi.org/10.1007/s10529-007-9627-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6968.2004.tb09638.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024112428"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6968.2004.tb09638.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024112428"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb.60014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024924022"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m405404200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025193067"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biortech.2012.12.106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025200509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2007.07.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025542436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-008-1555-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025631611", 
          "https://doi.org/10.1007/s00253-008-1555-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-008-1555-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025631611", 
          "https://doi.org/10.1007/s00253-008-1555-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jmb.2007.08.048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026821642"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jmb.2007.08.048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026821642"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pep.2003.12.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026909006"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/febs.12568", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027333167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m104483200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027899557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.anaerobe.2015.04.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028092395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.anaerobe.2015.04.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028092395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb.60548", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029001926"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m008083200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029722528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-014-6161-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029837562", 
          "https://doi.org/10.1007/s00253-014-6161-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijbiomac.2015.12.065", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030624980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aem.68.8.3948-3955.2002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034061998"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmcl.2012.10.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034144258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-011-3366-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034733401", 
          "https://doi.org/10.1007/s00253-011-3366-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jam.12294", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035044619"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.abb.2012.02.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035705989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-010-2669-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036504566", 
          "https://doi.org/10.1007/s00253-010-2669-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-010-2669-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036504566", 
          "https://doi.org/10.1007/s00253-010-2669-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00552-09", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037292406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jmb.2010.04.023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039673133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.compbiolchem.2008.03.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041211696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2958.2007.05891.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041252718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m513345200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041284313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep00063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041618792", 
          "https://doi.org/10.1038/srep00063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-3659(01)00405-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042043899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m804092200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042739951"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2013.02.070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044227226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2013.02.070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044227226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aem.69.8.4390-4395.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044760089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1018911316021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045210100", 
          "https://doi.org/10.1023/a:1018911316021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb.80872", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045628596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb.80872", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045628596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aem.71.12.7955-7960.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045790444"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11356-012-1221-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047501178", 
          "https://doi.org/10.1007/s11356-012-1221-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-006-0836-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048273076", 
          "https://doi.org/10.1007/s00253-006-0836-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-006-0836-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048273076", 
          "https://doi.org/10.1007/s00253-006-0836-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/07388551.2015.1004518", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049715506"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(90)90081-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050513446"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(90)90081-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050513446"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aem.02289-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051272574"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.abb.2007.03.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051344978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/193229681100500507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051355727"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/193229681100500507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051355727"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-003-1316-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052637966", 
          "https://doi.org/10.1007/s00253-003-1316-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biortech.2007.05.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052781465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aem.70.2.837-844.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053534084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0016-5085(98)70627-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053743702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acschembio.6b00852", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055135367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi052478r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055201503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi052478r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055201503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi1007194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055203297"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi1007194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055203297"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja407514z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055855229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja501632r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055856228"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm010852p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055946831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm010852p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055946831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm8016317", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055956241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm8016317", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055956241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/pr060502x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056291272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20150856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056717165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20150856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056717165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/00207713-51-5-1831", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060350641"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/00207713-51-5-1867", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060350645"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/mic.0.2008/019877-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060396469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/mic.0.27805-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060397382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/138920306776359786", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069179116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.21775/cimb.011.059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069253017"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.21775/cimb.012.043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069253034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2741/e400", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070917877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075767522", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078466598", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082759430", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.enzmictec.2017.02.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083750135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12866-017-1033-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085595865", 
          "https://doi.org/10.1186/s12866-017-1033-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12866-017-1033-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085595865", 
          "https://doi.org/10.1186/s12866-017-1033-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jmgm.2017.10.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092461311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.analchem.8b00554", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101825314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.analchem.8b00554", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101825314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40643-018-0206-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103666772", 
          "https://doi.org/10.1186/s40643-018-0206-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40643-018-0206-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103666772", 
          "https://doi.org/10.1186/s40643-018-0206-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jconrel.2018.05.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103906052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jconrel.2018.05.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103906052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2018.05.112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104123922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-018-9284-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106131234", 
          "https://doi.org/10.1007/s00253-018-9284-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11274-018-2530-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106912546", 
          "https://doi.org/10.1007/s11274-018-2530-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-018-9422-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107552997", 
          "https://doi.org/10.1007/s00253-018-9422-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-018-9422-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107552997", 
          "https://doi.org/10.1007/s00253-018-9422-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10529-019-02647-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1111365852", 
          "https://doi.org/10.1007/s10529-019-02647-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10529-019-02647-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1111365852", 
          "https://doi.org/10.1007/s10529-019-02647-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10529-019-02647-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1111365852", 
          "https://doi.org/10.1007/s10529-019-02647-9"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-04-03", 
    "datePublishedReg": "2019-04-03", 
    "description": "Azoreductases reductively cleave azo linkages by using NAD(P)H as an electron donor. The enzymes are widely found in bacteria and act on numerous azo dyes, which allow various unique applications. This review describes primary amino acid sequences, structures, substrates, physiological roles, and biotechnological applications of bacterial azoreductases to discuss their remarkable diversification. According to primary sequences, azoreductases were classified phylogenetically into four main clades. Most members of clades I-III are flavoproteins, whereas clade IV members include flavin-free azoreductases. Clades I and II prefer NADPH and NADH, respectively, as electron donors, whereas other members generally use both. Several enzymes formed no clades; moreover, some bacteria produce azoreductases with longer primary structures than those hitherto identified, which implies further diversification of bacterial azoreductases. The crystal structures commonly reveal the Rossmann folds; however, ternary structures are moderately varied with different quaternary conformation. Although physiological roles are obscure, several azoreductases have been shown to act on metabolites such as flavins, quinones, and metal ions more efficiently than on azo dyes. Considering that many homologs exclusively act on these metabolites, it is possible that azoreductases are actually side activities of versatile reductases that act on various substrates with different specificities. In parallel, this idea raises the possibility that homologous enzymes, even if these are already defined as other types of reductases, widely harbor azoreductase activities. Although azoreductases for which their genes have been identified are not abundant, it may be simple to identify azoreductases of biotechnological importance that have novel substrate specificities.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00253-019-09775-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1083533", 
        "issn": [
          "0175-7598", 
          "1432-0614"
        ], 
        "name": "Applied Microbiology and Biotechnology", 
        "type": "Periodical"
      }
    ], 
    "name": "Remarkable diversification of bacterial azoreductases: primary sequences, structures, substrates, physiological roles, and biotechnological applications", 
    "pagination": "1-14", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00253-019-09775-2"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d9a2aadeac7b9b5957ef769b10ab564fed2594b718a1653a2766c32e56daa620"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113179814"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8406612"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30941462"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00253-019-09775-2", 
      "https://app.dimensions.ai/details/publication/pub.1113179814"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T09:22", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000376_0000000376/records_56182_00000006.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00253-019-09775-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00253-019-09775-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00253-019-09775-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00253-019-09775-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00253-019-09775-2'


 

This table displays all metadata directly associated to this object as RDF triples.

398 TRIPLES      21 PREDICATES      130 URIs      18 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00253-019-09775-2 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author N55a9c53aac1844ac8244a933548182db
4 schema:citation sg:pub.10.1007/s00253-003-1316-5
5 sg:pub.10.1007/s00253-006-0836-1
6 sg:pub.10.1007/s00253-007-1087-5
7 sg:pub.10.1007/s00253-007-1212-5
8 sg:pub.10.1007/s00253-008-1555-6
9 sg:pub.10.1007/s00253-009-1911-1
10 sg:pub.10.1007/s00253-009-2351-7
11 sg:pub.10.1007/s00253-010-2669-1
12 sg:pub.10.1007/s00253-011-3366-4
13 sg:pub.10.1007/s00253-014-5896-z
14 sg:pub.10.1007/s00253-014-6161-1
15 sg:pub.10.1007/s00253-018-9284-y
16 sg:pub.10.1007/s00253-018-9422-6
17 sg:pub.10.1007/s10529-007-9627-8
18 sg:pub.10.1007/s10529-013-1338-8
19 sg:pub.10.1007/s10529-019-02647-9
20 sg:pub.10.1007/s10930-013-9522-1
21 sg:pub.10.1007/s11274-012-1198-8
22 sg:pub.10.1007/s11274-018-2530-8
23 sg:pub.10.1007/s11356-012-1221-5
24 sg:pub.10.1007/s13238-010-0090-2
25 sg:pub.10.1023/a:1018911316021
26 sg:pub.10.1038/srep00063
27 sg:pub.10.1186/1471-2091-11-13
28 sg:pub.10.1186/s12866-017-1033-3
29 sg:pub.10.1186/s40643-018-0206-8
30 https://app.dimensions.ai/details/publication/pub.1075767522
31 https://app.dimensions.ai/details/publication/pub.1078466598
32 https://app.dimensions.ai/details/publication/pub.1082759430
33 https://doi.org/10.1016/0006-2952(90)90081-u
34 https://doi.org/10.1016/j.abb.2007.03.003
35 https://doi.org/10.1016/j.abb.2012.02.010
36 https://doi.org/10.1016/j.addr.2004.08.008
37 https://doi.org/10.1016/j.anaerobe.2011.12.006
38 https://doi.org/10.1016/j.anaerobe.2015.04.007
39 https://doi.org/10.1016/j.bbrc.2018.05.112
40 https://doi.org/10.1016/j.biomaterials.2013.02.070
41 https://doi.org/10.1016/j.biortech.2007.05.027
42 https://doi.org/10.1016/j.biortech.2012.12.106
43 https://doi.org/10.1016/j.biortech.2013.09.124
44 https://doi.org/10.1016/j.bmcl.2011.09.071
45 https://doi.org/10.1016/j.bmcl.2012.10.006
46 https://doi.org/10.1016/j.compbiolchem.2008.03.003
47 https://doi.org/10.1016/j.enzmictec.2017.02.003
48 https://doi.org/10.1016/j.febslet.2007.07.039
49 https://doi.org/10.1016/j.ijbiomac.2015.12.065
50 https://doi.org/10.1016/j.ijpharm.2008.09.058
51 https://doi.org/10.1016/j.jconrel.2018.05.007
52 https://doi.org/10.1016/j.jmb.2007.08.048
53 https://doi.org/10.1016/j.jmb.2010.04.023
54 https://doi.org/10.1016/j.jmgm.2017.10.020
55 https://doi.org/10.1016/j.molcatb.2016.04.012
56 https://doi.org/10.1016/j.pep.2003.12.016
57 https://doi.org/10.1016/s0016-5085(98)70627-4
58 https://doi.org/10.1016/s0168-3659(01)00405-9
59 https://doi.org/10.1021/acs.analchem.8b00554
60 https://doi.org/10.1021/acschembio.6b00852
61 https://doi.org/10.1021/bi052478r
62 https://doi.org/10.1021/bi1007194
63 https://doi.org/10.1021/ja407514z
64 https://doi.org/10.1021/ja501632r
65 https://doi.org/10.1021/jm010852p
66 https://doi.org/10.1021/jm8016317
67 https://doi.org/10.1021/pr060502x
68 https://doi.org/10.1042/bj20150856
69 https://doi.org/10.1074/jbc.m002617200
70 https://doi.org/10.1074/jbc.m008083200
71 https://doi.org/10.1074/jbc.m104483200
72 https://doi.org/10.1074/jbc.m405404200
73 https://doi.org/10.1074/jbc.m513345200
74 https://doi.org/10.1074/jbc.m710070200
75 https://doi.org/10.1074/jbc.m804092200
76 https://doi.org/10.1074/mcp.m500394-mcp200
77 https://doi.org/10.1099/00207713-51-5-1831
78 https://doi.org/10.1099/00207713-51-5-1867
79 https://doi.org/10.1099/mic.0.2008/019877-0
80 https://doi.org/10.1099/mic.0.27805-0
81 https://doi.org/10.1107/s1399004713030988
82 https://doi.org/10.1107/s1744309109044741
83 https://doi.org/10.1110/ps.073029607
84 https://doi.org/10.1111/bph.13571
85 https://doi.org/10.1111/febs.12568
86 https://doi.org/10.1111/j.1365-2958.2007.05891.x
87 https://doi.org/10.1111/j.1574-6968.2004.tb09638.x
88 https://doi.org/10.1111/j.1574-6976.2008.00107.x
89 https://doi.org/10.1111/jam.12294
90 https://doi.org/10.1128/aem.02289-10
91 https://doi.org/10.1128/aem.68.8.3948-3955.2002
92 https://doi.org/10.1128/aem.69.8.4390-4395.2003
93 https://doi.org/10.1128/aem.70.2.837-844.2004
94 https://doi.org/10.1128/aem.71.12.7955-7960.2005
95 https://doi.org/10.1128/jb.00552-09
96 https://doi.org/10.1177/193229681100500507
97 https://doi.org/10.1271/bbb.110397
98 https://doi.org/10.1271/bbb.60014
99 https://doi.org/10.1271/bbb.60548
100 https://doi.org/10.1271/bbb.80872
101 https://doi.org/10.1371/journal.pone.0098551
102 https://doi.org/10.2147/dddt.s48636
103 https://doi.org/10.2174/138920306776359786
104 https://doi.org/10.21775/cimb.011.059
105 https://doi.org/10.21775/cimb.012.043
106 https://doi.org/10.2741/e400
107 https://doi.org/10.3109/07388551.2015.1004518
108 schema:datePublished 2019-04-03
109 schema:datePublishedReg 2019-04-03
110 schema:description Azoreductases reductively cleave azo linkages by using NAD(P)H as an electron donor. The enzymes are widely found in bacteria and act on numerous azo dyes, which allow various unique applications. This review describes primary amino acid sequences, structures, substrates, physiological roles, and biotechnological applications of bacterial azoreductases to discuss their remarkable diversification. According to primary sequences, azoreductases were classified phylogenetically into four main clades. Most members of clades I-III are flavoproteins, whereas clade IV members include flavin-free azoreductases. Clades I and II prefer NADPH and NADH, respectively, as electron donors, whereas other members generally use both. Several enzymes formed no clades; moreover, some bacteria produce azoreductases with longer primary structures than those hitherto identified, which implies further diversification of bacterial azoreductases. The crystal structures commonly reveal the Rossmann folds; however, ternary structures are moderately varied with different quaternary conformation. Although physiological roles are obscure, several azoreductases have been shown to act on metabolites such as flavins, quinones, and metal ions more efficiently than on azo dyes. Considering that many homologs exclusively act on these metabolites, it is possible that azoreductases are actually side activities of versatile reductases that act on various substrates with different specificities. In parallel, this idea raises the possibility that homologous enzymes, even if these are already defined as other types of reductases, widely harbor azoreductase activities. Although azoreductases for which their genes have been identified are not abundant, it may be simple to identify azoreductases of biotechnological importance that have novel substrate specificities.
111 schema:genre research_article
112 schema:inLanguage en
113 schema:isAccessibleForFree false
114 schema:isPartOf sg:journal.1083533
115 schema:name Remarkable diversification of bacterial azoreductases: primary sequences, structures, substrates, physiological roles, and biotechnological applications
116 schema:pagination 1-14
117 schema:productId N34052cffc289406f8fcf7692598cacc2
118 N56008792193745afbd2fd2f29e6d5da0
119 Nd8bd211fdb8a47a19d21b14674b0b665
120 Ndee88aafaceb424cb8c79f2ff4fada0e
121 Neab5c0bd3c7a41cfbc19fb814a1fe243
122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113179814
123 https://doi.org/10.1007/s00253-019-09775-2
124 schema:sdDatePublished 2019-04-15T09:22
125 schema:sdLicense https://scigraph.springernature.com/explorer/license/
126 schema:sdPublisher Nee596d6bfbd949bc9663f7bf186cf29e
127 schema:url https://link.springer.com/10.1007%2Fs00253-019-09775-2
128 sgo:license sg:explorer/license/
129 sgo:sdDataset articles
130 rdf:type schema:ScholarlyArticle
131 N34052cffc289406f8fcf7692598cacc2 schema:name nlm_unique_id
132 schema:value 8406612
133 rdf:type schema:PropertyValue
134 N346f35c28069481c96fae3db0d402059 schema:affiliation https://www.grid.ac/institutes/grid.265107.7
135 schema:familyName Suzuki
136 schema:givenName Hirokazu
137 rdf:type schema:Person
138 N55a9c53aac1844ac8244a933548182db rdf:first N346f35c28069481c96fae3db0d402059
139 rdf:rest rdf:nil
140 N56008792193745afbd2fd2f29e6d5da0 schema:name dimensions_id
141 schema:value pub.1113179814
142 rdf:type schema:PropertyValue
143 Nd8bd211fdb8a47a19d21b14674b0b665 schema:name doi
144 schema:value 10.1007/s00253-019-09775-2
145 rdf:type schema:PropertyValue
146 Ndee88aafaceb424cb8c79f2ff4fada0e schema:name pubmed_id
147 schema:value 30941462
148 rdf:type schema:PropertyValue
149 Neab5c0bd3c7a41cfbc19fb814a1fe243 schema:name readcube_id
150 schema:value d9a2aadeac7b9b5957ef769b10ab564fed2594b718a1653a2766c32e56daa620
151 rdf:type schema:PropertyValue
152 Nee596d6bfbd949bc9663f7bf186cf29e schema:name Springer Nature - SN SciGraph project
153 rdf:type schema:Organization
154 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
155 schema:name Biological Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
158 schema:name Biochemistry and Cell Biology
159 rdf:type schema:DefinedTerm
160 sg:journal.1083533 schema:issn 0175-7598
161 1432-0614
162 schema:name Applied Microbiology and Biotechnology
163 rdf:type schema:Periodical
164 sg:pub.10.1007/s00253-003-1316-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052637966
165 https://doi.org/10.1007/s00253-003-1316-5
166 rdf:type schema:CreativeWork
167 sg:pub.10.1007/s00253-006-0836-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048273076
168 https://doi.org/10.1007/s00253-006-0836-1
169 rdf:type schema:CreativeWork
170 sg:pub.10.1007/s00253-007-1087-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017167527
171 https://doi.org/10.1007/s00253-007-1087-5
172 rdf:type schema:CreativeWork
173 sg:pub.10.1007/s00253-007-1212-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010809249
174 https://doi.org/10.1007/s00253-007-1212-5
175 rdf:type schema:CreativeWork
176 sg:pub.10.1007/s00253-008-1555-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025631611
177 https://doi.org/10.1007/s00253-008-1555-6
178 rdf:type schema:CreativeWork
179 sg:pub.10.1007/s00253-009-1911-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015970605
180 https://doi.org/10.1007/s00253-009-1911-1
181 rdf:type schema:CreativeWork
182 sg:pub.10.1007/s00253-009-2351-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003156970
183 https://doi.org/10.1007/s00253-009-2351-7
184 rdf:type schema:CreativeWork
185 sg:pub.10.1007/s00253-010-2669-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036504566
186 https://doi.org/10.1007/s00253-010-2669-1
187 rdf:type schema:CreativeWork
188 sg:pub.10.1007/s00253-011-3366-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034733401
189 https://doi.org/10.1007/s00253-011-3366-4
190 rdf:type schema:CreativeWork
191 sg:pub.10.1007/s00253-014-5896-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1013552693
192 https://doi.org/10.1007/s00253-014-5896-z
193 rdf:type schema:CreativeWork
194 sg:pub.10.1007/s00253-014-6161-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029837562
195 https://doi.org/10.1007/s00253-014-6161-1
196 rdf:type schema:CreativeWork
197 sg:pub.10.1007/s00253-018-9284-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1106131234
198 https://doi.org/10.1007/s00253-018-9284-y
199 rdf:type schema:CreativeWork
200 sg:pub.10.1007/s00253-018-9422-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107552997
201 https://doi.org/10.1007/s00253-018-9422-6
202 rdf:type schema:CreativeWork
203 sg:pub.10.1007/s10529-007-9627-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023103702
204 https://doi.org/10.1007/s10529-007-9627-8
205 rdf:type schema:CreativeWork
206 sg:pub.10.1007/s10529-013-1338-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002710013
207 https://doi.org/10.1007/s10529-013-1338-8
208 rdf:type schema:CreativeWork
209 sg:pub.10.1007/s10529-019-02647-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111365852
210 https://doi.org/10.1007/s10529-019-02647-9
211 rdf:type schema:CreativeWork
212 sg:pub.10.1007/s10930-013-9522-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020271951
213 https://doi.org/10.1007/s10930-013-9522-1
214 rdf:type schema:CreativeWork
215 sg:pub.10.1007/s11274-012-1198-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016227358
216 https://doi.org/10.1007/s11274-012-1198-8
217 rdf:type schema:CreativeWork
218 sg:pub.10.1007/s11274-018-2530-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106912546
219 https://doi.org/10.1007/s11274-018-2530-8
220 rdf:type schema:CreativeWork
221 sg:pub.10.1007/s11356-012-1221-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047501178
222 https://doi.org/10.1007/s11356-012-1221-5
223 rdf:type schema:CreativeWork
224 sg:pub.10.1007/s13238-010-0090-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021614383
225 https://doi.org/10.1007/s13238-010-0090-2
226 rdf:type schema:CreativeWork
227 sg:pub.10.1023/a:1018911316021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045210100
228 https://doi.org/10.1023/a:1018911316021
229 rdf:type schema:CreativeWork
230 sg:pub.10.1038/srep00063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041618792
231 https://doi.org/10.1038/srep00063
232 rdf:type schema:CreativeWork
233 sg:pub.10.1186/1471-2091-11-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007202118
234 https://doi.org/10.1186/1471-2091-11-13
235 rdf:type schema:CreativeWork
236 sg:pub.10.1186/s12866-017-1033-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085595865
237 https://doi.org/10.1186/s12866-017-1033-3
238 rdf:type schema:CreativeWork
239 sg:pub.10.1186/s40643-018-0206-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103666772
240 https://doi.org/10.1186/s40643-018-0206-8
241 rdf:type schema:CreativeWork
242 https://app.dimensions.ai/details/publication/pub.1075767522 schema:CreativeWork
243 https://app.dimensions.ai/details/publication/pub.1078466598 schema:CreativeWork
244 https://app.dimensions.ai/details/publication/pub.1082759430 schema:CreativeWork
245 https://doi.org/10.1016/0006-2952(90)90081-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1050513446
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1016/j.abb.2007.03.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051344978
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1016/j.abb.2012.02.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035705989
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/j.addr.2004.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007961659
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/j.anaerobe.2011.12.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002673741
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/j.anaerobe.2015.04.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028092395
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/j.bbrc.2018.05.112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1104123922
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/j.biomaterials.2013.02.070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044227226
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/j.biortech.2007.05.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052781465
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/j.biortech.2012.12.106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025200509
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1016/j.biortech.2013.09.124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004732136
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/j.bmcl.2011.09.071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015281843
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/j.bmcl.2012.10.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034144258
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/j.compbiolchem.2008.03.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041211696
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1016/j.enzmictec.2017.02.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083750135
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1016/j.febslet.2007.07.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025542436
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1016/j.ijbiomac.2015.12.065 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030624980
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1016/j.ijpharm.2008.09.058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015877692
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1016/j.jconrel.2018.05.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103906052
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1016/j.jmb.2007.08.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026821642
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1016/j.jmb.2010.04.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039673133
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1016/j.jmgm.2017.10.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092461311
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1016/j.molcatb.2016.04.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016484839
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1016/j.pep.2003.12.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026909006
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1016/s0016-5085(98)70627-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053743702
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1016/s0168-3659(01)00405-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042043899
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1021/acs.analchem.8b00554 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101825314
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1021/acschembio.6b00852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055135367
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1021/bi052478r schema:sameAs https://app.dimensions.ai/details/publication/pub.1055201503
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1021/bi1007194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055203297
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1021/ja407514z schema:sameAs https://app.dimensions.ai/details/publication/pub.1055855229
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1021/ja501632r schema:sameAs https://app.dimensions.ai/details/publication/pub.1055856228
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1021/jm010852p schema:sameAs https://app.dimensions.ai/details/publication/pub.1055946831
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1021/jm8016317 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055956241
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1021/pr060502x schema:sameAs https://app.dimensions.ai/details/publication/pub.1056291272
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1042/bj20150856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056717165
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1074/jbc.m002617200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016518933
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1074/jbc.m008083200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029722528
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1074/jbc.m104483200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027899557
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1074/jbc.m405404200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025193067
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1074/jbc.m513345200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041284313
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1074/jbc.m710070200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007412399
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1074/jbc.m804092200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042739951
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1074/mcp.m500394-mcp200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004263446
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1099/00207713-51-5-1831 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060350641
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1099/00207713-51-5-1867 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060350645
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1099/mic.0.2008/019877-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060396469
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1099/mic.0.27805-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060397382
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1107/s1399004713030988 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019675446
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1107/s1744309109044741 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003707387
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1110/ps.073029607 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004120803
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1111/bph.13571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013570100
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1111/febs.12568 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027333167
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1111/j.1365-2958.2007.05891.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041252718
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1111/j.1574-6968.2004.tb09638.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024112428
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1111/j.1574-6976.2008.00107.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014835876
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1111/jam.12294 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035044619
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1128/aem.02289-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051272574
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1128/aem.68.8.3948-3955.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034061998
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1128/aem.69.8.4390-4395.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044760089
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1128/aem.70.2.837-844.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053534084
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1128/aem.71.12.7955-7960.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045790444
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1128/jb.00552-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037292406
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1177/193229681100500507 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051355727
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1271/bbb.110397 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002348122
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1271/bbb.60014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024924022
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1271/bbb.60548 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029001926
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1271/bbb.80872 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045628596
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1371/journal.pone.0098551 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020002736
382 rdf:type schema:CreativeWork
383 https://doi.org/10.2147/dddt.s48636 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017008022
384 rdf:type schema:CreativeWork
385 https://doi.org/10.2174/138920306776359786 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069179116
386 rdf:type schema:CreativeWork
387 https://doi.org/10.21775/cimb.011.059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069253017
388 rdf:type schema:CreativeWork
389 https://doi.org/10.21775/cimb.012.043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069253034
390 rdf:type schema:CreativeWork
391 https://doi.org/10.2741/e400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070917877
392 rdf:type schema:CreativeWork
393 https://doi.org/10.3109/07388551.2015.1004518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049715506
394 rdf:type schema:CreativeWork
395 https://www.grid.ac/institutes/grid.265107.7 schema:alternateName Tottori University
396 schema:name Center for Research on Green Sustainable Chemistry, Tottori University, 4-101 Koyama-Minami, 680-8552, Tottori, Japan
397 Faculty of Engineering, Tottori University, 4-101 Koyama-Minami, 680-8552, Tottori, Japan
398 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...