Critical factors for the replication of mumps virus in primary chicken embryo fibroblasts defined by the use of design of ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-02

AUTHORS

Maja Markusic, Nediljko Pavlović, Maja Šantak, Gorana Marić, Ljerka Kotarski, Dubravko Forcic

ABSTRACT

Live attenuated vaccines against mumps virus (MuV) have been traditionally produced by passaging the virus in the embryonated chicken eggs or primary chicken embryo fibroblasts (CEFs). Virus propagation on these cell substrates enables successful virus attenuation and retains it sufficiently antigenic to induce lasting protective immunity in humans. The aim of this study was to identify critical factors for MuV replication in primary CEFs grown on a small-scale level in order to explore possibilities for improvements in the virus replication and yield. The effect of differently prepared cells, culturing conditions, and infection conditions on virus yield was estimated by employing statistical design of experiments (DoE) methodology. Our results show that the preparation of primary CEFs and the way of their infection substantially impact virus yield and are critical for efficient MuV replication. These process parameters should be considered in further process optimization. We also demonstrate the applicability of DoE in optimization of virus replication as a crucial step in obtaining high virus yields. More... »

PAGES

1533-1541

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00253-012-4394-4

DOI

http://dx.doi.org/10.1007/s00253-012-4394-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001978145

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22996276


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cells, Cultured", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chick Embryo", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fibroblasts", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mumps virus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Research Design", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Virus Cultivation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Virus Replication", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute of Immunology", 
          "id": "https://www.grid.ac/institutes/grid.418761.d", 
          "name": [
            "Molecular Biomedicine Unit, Institute of Immunology, Rockefellerova 10, 10000, Zagreb, Croatia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Markusic", 
        "givenName": "Maja", 
        "id": "sg:person.01065146467.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065146467.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Immunology", 
          "id": "https://www.grid.ac/institutes/grid.418761.d", 
          "name": [
            "Research and Development Department, Institute of Immunology, Rockefellerova 10, 10000, Zagreb, Croatia", 
            "Kutrilin TPV, Radni\u010dka 173p, 10000, Zagreb, Croatia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pavlovi\u0107", 
        "givenName": "Nediljko", 
        "id": "sg:person.01222420345.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222420345.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Immunology", 
          "id": "https://www.grid.ac/institutes/grid.418761.d", 
          "name": [
            "Molecular Biomedicine Unit, Institute of Immunology, Rockefellerova 10, 10000, Zagreb, Croatia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "\u0160antak", 
        "givenName": "Maja", 
        "id": "sg:person.0634471467.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634471467.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Immunology", 
          "id": "https://www.grid.ac/institutes/grid.418761.d", 
          "name": [
            "Vaccine Production Unit, Institute of Immunology, Rockefellerova 5, 10000, Zagreb, Croatia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mari\u0107", 
        "givenName": "Gorana", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Immunology", 
          "id": "https://www.grid.ac/institutes/grid.418761.d", 
          "name": [
            "Vaccine Production Unit, Institute of Immunology, Rockefellerova 5, 10000, Zagreb, Croatia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kotarski", 
        "givenName": "Ljerka", 
        "id": "sg:person.0675600070.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675600070.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Immunology", 
          "id": "https://www.grid.ac/institutes/grid.418761.d", 
          "name": [
            "Molecular Biomedicine Unit, Institute of Immunology, Rockefellerova 10, 10000, Zagreb, Croatia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Forcic", 
        "givenName": "Dubravko", 
        "id": "sg:person.01053320451.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053320451.59"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/1045-1056(91)90036-j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000950387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jviromet.2005.01.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013776215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.micinf.2010.08.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026463454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02624162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041446166", 
          "https://doi.org/10.1007/bf02624162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02624162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041446166", 
          "https://doi.org/10.1007/bf02624162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.vaccine.2009.11.049", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042546296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/btpr.67", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047467599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-1157(89)90031-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047863670"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01641272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049731650", 
          "https://doi.org/10.1007/bf01641272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01641272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049731650", 
          "https://doi.org/10.1007/bf01641272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0731-7085(00)00529-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050104810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.vaccine.2004.10.035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052425980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074369803", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076429877", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077373567", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079819724", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-02", 
    "datePublishedReg": "2013-02-01", 
    "description": "Live attenuated vaccines against mumps virus (MuV) have been traditionally produced by passaging the virus in the embryonated chicken eggs or primary chicken embryo fibroblasts (CEFs). Virus propagation on these cell substrates enables successful virus attenuation and retains it sufficiently antigenic to induce lasting protective immunity in humans. The aim of this study was to identify critical factors for MuV replication in primary CEFs grown on a small-scale level in order to explore possibilities for improvements in the virus replication and yield. The effect of differently prepared cells, culturing conditions, and infection conditions on virus yield was estimated by employing statistical design of experiments (DoE) methodology. Our results show that the preparation of primary CEFs and the way of their infection substantially impact virus yield and are critical for efficient MuV replication. These process parameters should be considered in further process optimization. We also demonstrate the applicability of DoE in optimization of virus replication as a crucial step in obtaining high virus yields.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00253-012-4394-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1083533", 
        "issn": [
          "0175-7598", 
          "1432-0614"
        ], 
        "name": "Applied Microbiology and Biotechnology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "97"
      }
    ], 
    "name": "Critical factors for the replication of mumps virus in primary chicken embryo fibroblasts defined by the use of design of experiments (DoE)", 
    "pagination": "1533-1541", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "096be1803522514e312ddb4648c283d9b50819e3e83a5be1be176a1db19b416f"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "22996276"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8406612"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00253-012-4394-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1001978145"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00253-012-4394-4", 
      "https://app.dimensions.ai/details/publication/pub.1001978145"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000509.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00253-012-4394-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00253-012-4394-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00253-012-4394-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00253-012-4394-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00253-012-4394-4'


 

This table displays all metadata directly associated to this object as RDF triples.

178 TRIPLES      21 PREDICATES      51 URIs      29 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00253-012-4394-4 schema:about N0490ccd9c9404df8a618e1fe56a18cf6
2 N41f256dfb3bf4f06b230e359f2e047bd
3 N83ab821babaf45219b215c374e648e73
4 N9bef11081c24470696f7a46ba0bdcf5b
5 Na3ca977940454b919b7064007afc640f
6 Nb0bcfcfe294c4308aa3936d28761416e
7 Nbb1482ade82e47b99cc323bb3d8b1380
8 Nfb875585bf5647bf9280c9a4432d9b3c
9 anzsrc-for:11
10 anzsrc-for:1108
11 schema:author N0f4ee47b96ac4b109c7fa054eeb1f294
12 schema:citation sg:pub.10.1007/bf01641272
13 sg:pub.10.1007/bf02624162
14 https://app.dimensions.ai/details/publication/pub.1074369803
15 https://app.dimensions.ai/details/publication/pub.1076429877
16 https://app.dimensions.ai/details/publication/pub.1077373567
17 https://app.dimensions.ai/details/publication/pub.1079819724
18 https://doi.org/10.1002/btpr.67
19 https://doi.org/10.1016/0092-1157(89)90031-0
20 https://doi.org/10.1016/1045-1056(91)90036-j
21 https://doi.org/10.1016/j.jviromet.2005.01.032
22 https://doi.org/10.1016/j.micinf.2010.08.004
23 https://doi.org/10.1016/j.vaccine.2004.10.035
24 https://doi.org/10.1016/j.vaccine.2009.11.049
25 https://doi.org/10.1016/s0731-7085(00)00529-x
26 schema:datePublished 2013-02
27 schema:datePublishedReg 2013-02-01
28 schema:description Live attenuated vaccines against mumps virus (MuV) have been traditionally produced by passaging the virus in the embryonated chicken eggs or primary chicken embryo fibroblasts (CEFs). Virus propagation on these cell substrates enables successful virus attenuation and retains it sufficiently antigenic to induce lasting protective immunity in humans. The aim of this study was to identify critical factors for MuV replication in primary CEFs grown on a small-scale level in order to explore possibilities for improvements in the virus replication and yield. The effect of differently prepared cells, culturing conditions, and infection conditions on virus yield was estimated by employing statistical design of experiments (DoE) methodology. Our results show that the preparation of primary CEFs and the way of their infection substantially impact virus yield and are critical for efficient MuV replication. These process parameters should be considered in further process optimization. We also demonstrate the applicability of DoE in optimization of virus replication as a crucial step in obtaining high virus yields.
29 schema:genre research_article
30 schema:inLanguage en
31 schema:isAccessibleForFree false
32 schema:isPartOf Nc78d5f1734384a72abfb58b54d9367c8
33 Ne44e29e4a683421e93e301c5d228d339
34 sg:journal.1083533
35 schema:name Critical factors for the replication of mumps virus in primary chicken embryo fibroblasts defined by the use of design of experiments (DoE)
36 schema:pagination 1533-1541
37 schema:productId N0988035620024ef98183af82cd6b77eb
38 N137f2967520b4816982e5ecc7148daf2
39 N6c5e2ece45a44c2b9cf767f5cc64dd7e
40 N9c5008413d774f1182b5cc329de7c9b2
41 Nfdc2d5c5b3ed40be984d5530a2737b00
42 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001978145
43 https://doi.org/10.1007/s00253-012-4394-4
44 schema:sdDatePublished 2019-04-10T17:31
45 schema:sdLicense https://scigraph.springernature.com/explorer/license/
46 schema:sdPublisher Na11d4bb98b86434d981b72c2d361eefa
47 schema:url http://link.springer.com/10.1007%2Fs00253-012-4394-4
48 sgo:license sg:explorer/license/
49 sgo:sdDataset articles
50 rdf:type schema:ScholarlyArticle
51 N0490ccd9c9404df8a618e1fe56a18cf6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
52 schema:name Research Design
53 rdf:type schema:DefinedTerm
54 N0988035620024ef98183af82cd6b77eb schema:name pubmed_id
55 schema:value 22996276
56 rdf:type schema:PropertyValue
57 N0ccdf7a693d14a45876fea2859545721 rdf:first sg:person.0675600070.30
58 rdf:rest N6138fcfecb99426eb210ccb7dfe43cd9
59 N0f4ee47b96ac4b109c7fa054eeb1f294 rdf:first sg:person.01065146467.82
60 rdf:rest N3c0cb83df5dd4650af7e1d9adc131fa4
61 N11dd8e59911348b4b3af7af6b3e39b96 schema:affiliation https://www.grid.ac/institutes/grid.418761.d
62 schema:familyName Marić
63 schema:givenName Gorana
64 rdf:type schema:Person
65 N137f2967520b4816982e5ecc7148daf2 schema:name readcube_id
66 schema:value 096be1803522514e312ddb4648c283d9b50819e3e83a5be1be176a1db19b416f
67 rdf:type schema:PropertyValue
68 N1592ad6b7ec04bf1a9c6c0fb8b2a7a8f rdf:first N11dd8e59911348b4b3af7af6b3e39b96
69 rdf:rest N0ccdf7a693d14a45876fea2859545721
70 N3c0cb83df5dd4650af7e1d9adc131fa4 rdf:first sg:person.01222420345.88
71 rdf:rest N9924bd738eb741b881630a9577cd6c1f
72 N41f256dfb3bf4f06b230e359f2e047bd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Virus Replication
74 rdf:type schema:DefinedTerm
75 N6138fcfecb99426eb210ccb7dfe43cd9 rdf:first sg:person.01053320451.59
76 rdf:rest rdf:nil
77 N6c5e2ece45a44c2b9cf767f5cc64dd7e schema:name doi
78 schema:value 10.1007/s00253-012-4394-4
79 rdf:type schema:PropertyValue
80 N83ab821babaf45219b215c374e648e73 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Virus Cultivation
82 rdf:type schema:DefinedTerm
83 N9924bd738eb741b881630a9577cd6c1f rdf:first sg:person.0634471467.06
84 rdf:rest N1592ad6b7ec04bf1a9c6c0fb8b2a7a8f
85 N9bef11081c24470696f7a46ba0bdcf5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Cells, Cultured
87 rdf:type schema:DefinedTerm
88 N9c5008413d774f1182b5cc329de7c9b2 schema:name nlm_unique_id
89 schema:value 8406612
90 rdf:type schema:PropertyValue
91 Na11d4bb98b86434d981b72c2d361eefa schema:name Springer Nature - SN SciGraph project
92 rdf:type schema:Organization
93 Na3ca977940454b919b7064007afc640f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Fibroblasts
95 rdf:type schema:DefinedTerm
96 Nb0bcfcfe294c4308aa3936d28761416e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Mumps virus
98 rdf:type schema:DefinedTerm
99 Nbb1482ade82e47b99cc323bb3d8b1380 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Animals
101 rdf:type schema:DefinedTerm
102 Nc78d5f1734384a72abfb58b54d9367c8 schema:volumeNumber 97
103 rdf:type schema:PublicationVolume
104 Ne44e29e4a683421e93e301c5d228d339 schema:issueNumber 4
105 rdf:type schema:PublicationIssue
106 Nfb875585bf5647bf9280c9a4432d9b3c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Chick Embryo
108 rdf:type schema:DefinedTerm
109 Nfdc2d5c5b3ed40be984d5530a2737b00 schema:name dimensions_id
110 schema:value pub.1001978145
111 rdf:type schema:PropertyValue
112 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
113 schema:name Medical and Health Sciences
114 rdf:type schema:DefinedTerm
115 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
116 schema:name Medical Microbiology
117 rdf:type schema:DefinedTerm
118 sg:journal.1083533 schema:issn 0175-7598
119 1432-0614
120 schema:name Applied Microbiology and Biotechnology
121 rdf:type schema:Periodical
122 sg:person.01053320451.59 schema:affiliation https://www.grid.ac/institutes/grid.418761.d
123 schema:familyName Forcic
124 schema:givenName Dubravko
125 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053320451.59
126 rdf:type schema:Person
127 sg:person.01065146467.82 schema:affiliation https://www.grid.ac/institutes/grid.418761.d
128 schema:familyName Markusic
129 schema:givenName Maja
130 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065146467.82
131 rdf:type schema:Person
132 sg:person.01222420345.88 schema:affiliation https://www.grid.ac/institutes/grid.418761.d
133 schema:familyName Pavlović
134 schema:givenName Nediljko
135 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222420345.88
136 rdf:type schema:Person
137 sg:person.0634471467.06 schema:affiliation https://www.grid.ac/institutes/grid.418761.d
138 schema:familyName Šantak
139 schema:givenName Maja
140 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634471467.06
141 rdf:type schema:Person
142 sg:person.0675600070.30 schema:affiliation https://www.grid.ac/institutes/grid.418761.d
143 schema:familyName Kotarski
144 schema:givenName Ljerka
145 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675600070.30
146 rdf:type schema:Person
147 sg:pub.10.1007/bf01641272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049731650
148 https://doi.org/10.1007/bf01641272
149 rdf:type schema:CreativeWork
150 sg:pub.10.1007/bf02624162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041446166
151 https://doi.org/10.1007/bf02624162
152 rdf:type schema:CreativeWork
153 https://app.dimensions.ai/details/publication/pub.1074369803 schema:CreativeWork
154 https://app.dimensions.ai/details/publication/pub.1076429877 schema:CreativeWork
155 https://app.dimensions.ai/details/publication/pub.1077373567 schema:CreativeWork
156 https://app.dimensions.ai/details/publication/pub.1079819724 schema:CreativeWork
157 https://doi.org/10.1002/btpr.67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047467599
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/0092-1157(89)90031-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047863670
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/1045-1056(91)90036-j schema:sameAs https://app.dimensions.ai/details/publication/pub.1000950387
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1016/j.jviromet.2005.01.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013776215
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1016/j.micinf.2010.08.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026463454
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1016/j.vaccine.2004.10.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052425980
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/j.vaccine.2009.11.049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042546296
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/s0731-7085(00)00529-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050104810
172 rdf:type schema:CreativeWork
173 https://www.grid.ac/institutes/grid.418761.d schema:alternateName Institute of Immunology
174 schema:name Kutrilin TPV, Radnička 173p, 10000, Zagreb, Croatia
175 Molecular Biomedicine Unit, Institute of Immunology, Rockefellerova 10, 10000, Zagreb, Croatia
176 Research and Development Department, Institute of Immunology, Rockefellerova 10, 10000, Zagreb, Croatia
177 Vaccine Production Unit, Institute of Immunology, Rockefellerova 5, 10000, Zagreb, Croatia
178 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...