Fumaric acid production by fermentation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-03

AUTHORS

Carol A. Roa Engel, Adrie J. J. Straathof, Tiemen W. Zijlmans, Walter M. van Gulik, Luuk A. M. van der Wielen

ABSTRACT

The potential of fumaric acid as a raw material in the polymer industry and the increment of cost of petroleum-based fumaric acid raises interest in fermentation processes for production of this compound from renewable resources. Although the chemical process yields 112% w/w fumaric acid from maleic anhydride and the fermentation process yields only 85% w/w from glucose, the latter raw material is three times cheaper. Besides, the fermentation fixes CO2. Production of fumaric acid by Rhizopus species and the involved metabolic pathways are reviewed. Submerged fermentation systems coupled with product recovery techniques seem to have achieved economically attractive yields and productivities. Future prospects for improvement of fumaric acid production include metabolic engineering approaches to achieve low pH fermentations. More... »

PAGES

379-389

References to SciGraph publications

  • 1991-10. Optimization of fumaric acid production from potato flour by Rhizopus arrhizus in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 1989-10. Transport of l(-)malic acid and other dicarboxylic acids in the yeast Candida sphaerica in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 2000-07. Direct ammonium fumarate production by Rhizopus arrhizus under phosphorous limitation in BIOTECHNOLOGY LETTERS
  • 2004. Organic Acid Production by Filamentous Fungi in ADVANCES IN FUNGAL BIOTECHNOLOGY FOR INDUSTRY, AGRICULTURE, AND MEDICINE
  • 1989-12. Isoenzyme pattern and subcellular localisation of enzymes involved in fumaric acid accumulation by Rhizopus oryzae in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 2000-12. Differential uptake of fumarate by Candida utilis and Schizosaccharomyces pombe in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 1999-05. Biotechnology of succinic acid production and markets for derived industrial products in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 1990-03. Economic comparison of calcium fumarate and sodium fumarate production byRhizopus arrhizus in APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
  • 1989-10. Fumaric acid production from xylose by immobilized Rhizopus arrhizus cells in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 1997-03. Fumaric acid production in airlift loop reactor with porous sparger in APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
  • 1997. Production of Fumaric Acid by Immobilized Rhizopus Using Rotary Biofilm Contactor in BIOTECHNOLOGY FOR FUELS AND CHEMICALS
  • 1997-03. Production of fumaric acid by immobilized rhizopus using rotary biofilm contactor in APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
  • 2007-09. Prospects for a bio-based succinate industry in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 2004-12. Industrial bioconversion of renewable resources as an alternative to conventional chemistry in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 2002-09. Comparison of fumaric acid production by Rhizopus oryzae using different neutralizing agents in BIOPROCESS AND BIOSYSTEMS ENGINEERING
  • 2007-02. Production of lactic acid and byproducts from waste potato starch by Rhizopus arrhizus: role of nitrogen sources in WORLD JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
  • 2000-03. Mycelial pellet formation by Rhizopus oryzae ATCC 20344 in APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
  • Journal

    TITLE

    Applied Microbiology and Biotechnology

    ISSUE

    3

    VOLUME

    78

    Author Affiliations

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00253-007-1341-x

    DOI

    http://dx.doi.org/10.1007/s00253-007-1341-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1012233424

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/18214471


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