Influence of the shape of phospholipid vesicles on the measurement of their size by photon correlation spectroscopy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-09

AUTHORS

Laurent Beney, Elodie Linares, Eric Ferret, P. Gervais

ABSTRACT

The influence of shape transformation of large unilamellar vesicles (LUV) on their size measurement by photon correlation spectroscopy (PCS) has been investigated. The experimental size of vesicles after hyperosmotic contractions of increasing intensities have been compared to the theoretical volume decrease determined by applying Boyle Van't Hoff's law. The main observation is that PCS size measurement gives overestimated values when LUV have been subjected to a volume decrease of more than 20% of their initial volume. The PCS size overestimation is related to the influence of the shape transformation of the vesicles on their diffusion coefficient (D) as shown by modelling the evolution of D of a sphere which is transformed into an ellipsoid by internal volume reduction under constant area. More... »

PAGES

567-574

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s002490050167

DOI

http://dx.doi.org/10.1007/s002490050167

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043497221

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9791939


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