Magnetic-resonance-guided focused ultrasound treatment of non-spinal osteoid osteoma in children: multicentre experience View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-05-25

AUTHORS

Francesco Arrigoni, Alessandro Napoli, Alberto Bazzocchi, Luigi Zugaro, Roberto Scipione, Federico Bruno, Pierpaolo Palumbo, Michele Anzidei, Daniele Mercatelli, Giovanni Luca Gravina, Carmine Zoccali, Pejman Ghanouni, Antonio Barile, Carlo Catalano, Carlo Masciocchi

ABSTRACT

BackgroundOsteoid osteoma is a benign and painful musculoskeletal tumour that usually affects children. Current standard treatment is CT-guided radiofrequency ablation, a minimally invasive percutaneous procedure, with clinical success rates ranging between 85% and 98%. Though minimally invasive, however, this type of procedure is not free from complications.ObjectiveTo investigate the efficacy and safety of magnetic resonance (MR)-guided focused ultrasound (MRgFUS), a needleless procedure of thermal ablation employed in the treatment of non-spinal osteoid osteoma in paediatric patients.Materials and methodsWe report the results of 33 procedures of ablation of osteoid osteoma performed with MRgFUS in three university hospitals. To ablate a lesion on the bone surface, MRgFUS employs the ultrasound energy transduced along the soft tissue. The follow-up studies lasted 24 months and were performed combining clinical and imaging data.ResultsMean age of the children was 13.8 years. The clinical outcome showed a primary success of 97%. One case alone was submitted to repeat treatment because the first one failed (secondary success). No major or minor complications were recorded. During the investigation time, no relapse of symptomatology or delayed complications were observed.ConclusionAlthough our study is preliminary and limited by a low number of patients, our data show that MRgFUS is effective. This suggests that it might be useful as the first-line treatment in paediatric patients with osteoid osteoma. More... »

PAGES

1209-1216

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00247-019-04426-0

DOI

http://dx.doi.org/10.1007/s00247-019-04426-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1115676270

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/31129699


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "High-Intensity Focused Ultrasound Ablation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Imaging, Interventional", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Osteoma, Osteoid", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Emergency Radiology, San Salvatore Hospital, via Vetoio, 67100, L\u2019Aquila, Italy", 
          "id": "http://www.grid.ac/institutes/grid.415103.2", 
          "name": [
            "Department of Emergency Radiology, San Salvatore Hospital, via Vetoio, 67100, L\u2019Aquila, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arrigoni", 
        "givenName": "Francesco", 
        "id": "sg:person.01161200444.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161200444.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy", 
          "id": "http://www.grid.ac/institutes/grid.7841.a", 
          "name": [
            "Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Napoli", 
        "givenName": "Alessandro", 
        "id": "sg:person.01351075172.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351075172.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Via G. C. Pupilli 1, 40136, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419038.7", 
          "name": [
            "Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Via G. C. Pupilli 1, 40136, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bazzocchi", 
        "givenName": "Alberto", 
        "id": "sg:person.01236303515.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236303515.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Emergency Radiology, San Salvatore Hospital, via Vetoio, 67100, L\u2019Aquila, Italy", 
          "id": "http://www.grid.ac/institutes/grid.415103.2", 
          "name": [
            "Department of Emergency Radiology, San Salvatore Hospital, via Vetoio, 67100, L\u2019Aquila, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zugaro", 
        "givenName": "Luigi", 
        "id": "sg:person.0752660313.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752660313.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy", 
          "id": "http://www.grid.ac/institutes/grid.7841.a", 
          "name": [
            "Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Scipione", 
        "givenName": "Roberto", 
        "id": "sg:person.0734545107.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734545107.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy", 
          "id": "http://www.grid.ac/institutes/grid.158820.6", 
          "name": [
            "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bruno", 
        "givenName": "Federico", 
        "id": "sg:person.01234446237.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234446237.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy", 
          "id": "http://www.grid.ac/institutes/grid.158820.6", 
          "name": [
            "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Palumbo", 
        "givenName": "Pierpaolo", 
        "id": "sg:person.013062315016.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013062315016.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy", 
          "id": "http://www.grid.ac/institutes/grid.7841.a", 
          "name": [
            "Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Anzidei", 
        "givenName": "Michele", 
        "id": "sg:person.0735362216.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735362216.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Via G. C. Pupilli 1, 40136, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419038.7", 
          "name": [
            "Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Via G. C. Pupilli 1, 40136, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mercatelli", 
        "givenName": "Daniele", 
        "id": "sg:person.01365667157.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365667157.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy", 
          "id": "http://www.grid.ac/institutes/grid.158820.6", 
          "name": [
            "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gravina", 
        "givenName": "Giovanni Luca", 
        "id": "sg:person.0703131174.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0703131174.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Oncological Orthopedics Department, Regina Elena National Cancer Institute, Rome, Italy", 
          "id": "http://www.grid.ac/institutes/grid.417520.5", 
          "name": [
            "Oncological Orthopedics Department, Regina Elena National Cancer Institute, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zoccali", 
        "givenName": "Carmine", 
        "id": "sg:person.01255360757.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255360757.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Radiology, Stanford University Medical Center, Stanford, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.240952.8", 
          "name": [
            "Department of Radiology, Stanford University Medical Center, Stanford, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ghanouni", 
        "givenName": "Pejman", 
        "id": "sg:person.0723333404.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723333404.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy", 
          "id": "http://www.grid.ac/institutes/grid.158820.6", 
          "name": [
            "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barile", 
        "givenName": "Antonio", 
        "id": "sg:person.01372177461.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372177461.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy", 
          "id": "http://www.grid.ac/institutes/grid.7841.a", 
          "name": [
            "Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Catalano", 
        "givenName": "Carlo", 
        "id": "sg:person.01250755056.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250755056.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy", 
          "id": "http://www.grid.ac/institutes/grid.158820.6", 
          "name": [
            "Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila Via Giovanni Di Vincenzo, L\u2019Aquila, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Masciocchi", 
        "givenName": "Carlo", 
        "id": "sg:person.01215554212.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215554212.39"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s11547-014-0414-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013490274", 
          "https://doi.org/10.1007/s11547-014-0414-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00270-013-0815-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034766544", 
          "https://doi.org/10.1007/s00270-013-0815-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-017-0909-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083912583", 
          "https://doi.org/10.1007/s12032-017-0909-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-015-4111-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003229122", 
          "https://doi.org/10.1007/s00330-015-4111-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00247-005-0032-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010523694", 
          "https://doi.org/10.1007/s00247-005-0032-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-017-0904-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084033802", 
          "https://doi.org/10.1007/s12032-017-0904-7"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-05-25", 
    "datePublishedReg": "2019-05-25", 
    "description": "BackgroundOsteoid osteoma is a benign and painful musculoskeletal tumour that usually affects children. Current standard treatment is CT-guided radiofrequency ablation, a minimally invasive percutaneous procedure, with clinical success rates ranging between 85% and 98%. Though minimally invasive, however, this type of procedure is not free from complications.ObjectiveTo investigate the efficacy and safety of magnetic resonance (MR)-guided focused ultrasound (MRgFUS), a needleless procedure of thermal ablation employed in the treatment of non-spinal osteoid osteoma in paediatric patients.Materials and methodsWe report the results of 33 procedures of ablation of osteoid osteoma performed with MRgFUS in three university hospitals. To ablate a lesion on the bone surface, MRgFUS employs the ultrasound energy transduced along the soft tissue. The follow-up studies lasted 24\u00a0months and were performed combining clinical and imaging data.ResultsMean age of the children was 13.8\u00a0years. The clinical outcome showed a primary success of 97%. One case alone was submitted to repeat treatment because the first one failed (secondary success). No major or minor complications were recorded. During the investigation time, no relapse of symptomatology or delayed complications were observed.ConclusionAlthough our study is preliminary and limited by a low number of patients, our data show that MRgFUS is effective. This suggests that it might be useful as the first-line treatment in paediatric patients with osteoid osteoma.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00247-019-04426-0", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1016713", 
        "issn": [
          "0301-0449", 
          "1432-1998"
        ], 
        "name": "Pediatric Radiology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "9", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "49"
      }
    ], 
    "keywords": [
      "non-spinal osteoid osteoma", 
      "osteoid osteoma", 
      "pediatric patients", 
      "CT-guided radiofrequency ablation", 
      "first-line treatment", 
      "clinical success rate", 
      "current standard treatment", 
      "type of procedure", 
      "invasive percutaneous procedures", 
      "ResultsMean age", 
      "procedure of ablation", 
      "minor complications", 
      "clinical outcomes", 
      "multicentre experience", 
      "standard treatment", 
      "University Hospital", 
      "focused ultrasound treatment", 
      "musculoskeletal tumors", 
      "radiofrequency ablation", 
      "primary success", 
      "BackgroundOsteoid osteoma", 
      "percutaneous procedures", 
      "osteoma", 
      "complications", 
      "patients", 
      "soft tissue", 
      "MRgFUS", 
      "success rate", 
      "thermal ablation", 
      "treatment", 
      "bone surface", 
      "focused ultrasound", 
      "children", 
      "ablation", 
      "investigation time", 
      "magnetic resonance", 
      "imaging data", 
      "low number", 
      "relapse", 
      "hospital", 
      "ObjectiveTo", 
      "tumors", 
      "lesions", 
      "follow", 
      "MethodsWe", 
      "ConclusionAlthough", 
      "symptomatology", 
      "ultrasound energy", 
      "months", 
      "efficacy", 
      "ultrasound treatment", 
      "ultrasound", 
      "age", 
      "outcomes", 
      "procedure", 
      "study", 
      "tissue", 
      "safety", 
      "years", 
      "data", 
      "cases", 
      "rate", 
      "experience", 
      "number", 
      "types", 
      "success", 
      "time", 
      "results", 
      "resonance", 
      "materials", 
      "surface", 
      "energy", 
      "painful musculoskeletal tumour", 
      "needleless procedure", 
      "relapse of symptomatology"
    ], 
    "name": "Magnetic-resonance-guided focused ultrasound treatment of non-spinal osteoid osteoma in children: multicentre experience", 
    "pagination": "1209-1216", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1115676270"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00247-019-04426-0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "31129699"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00247-019-04426-0", 
      "https://app.dimensions.ai/details/publication/pub.1115676270"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:54", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_823.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00247-019-04426-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00247-019-04426-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00247-019-04426-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00247-019-04426-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00247-019-04426-0'


 

This table displays all metadata directly associated to this object as RDF triples.

310 TRIPLES      22 PREDICATES      116 URIs      102 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00247-019-04426-0 schema:about N0e314ed4e18c4c528f3b43fd1b63036d
2 N10b02ee97fa4435aa3e15e0505343ae6
3 Nb8db8aa63a604646abd4f0ab49bc7d45
4 Nc16fcd00f0894e0184ea60c23229a059
5 Nca402a8bdb934890994e588e1b20fe09
6 Nd452a3aebe5e4465bc831238a80cfee1
7 Ne617fd26afe741e787184d9dbf03abd1
8 Nf15951cab1d4463abcadd9ed86bbd7c8
9 Nf266835d4e46434aaed98d2820559e5d
10 anzsrc-for:11
11 anzsrc-for:1103
12 schema:author N823ec8ae564c41f9b0b41f92aa2aeef3
13 schema:citation sg:pub.10.1007/s00247-005-0032-y
14 sg:pub.10.1007/s00270-013-0815-8
15 sg:pub.10.1007/s00330-015-4111-7
16 sg:pub.10.1007/s11547-014-0414-z
17 sg:pub.10.1007/s12032-017-0904-7
18 sg:pub.10.1007/s12032-017-0909-2
19 schema:datePublished 2019-05-25
20 schema:datePublishedReg 2019-05-25
21 schema:description BackgroundOsteoid osteoma is a benign and painful musculoskeletal tumour that usually affects children. Current standard treatment is CT-guided radiofrequency ablation, a minimally invasive percutaneous procedure, with clinical success rates ranging between 85% and 98%. Though minimally invasive, however, this type of procedure is not free from complications.ObjectiveTo investigate the efficacy and safety of magnetic resonance (MR)-guided focused ultrasound (MRgFUS), a needleless procedure of thermal ablation employed in the treatment of non-spinal osteoid osteoma in paediatric patients.Materials and methodsWe report the results of 33 procedures of ablation of osteoid osteoma performed with MRgFUS in three university hospitals. To ablate a lesion on the bone surface, MRgFUS employs the ultrasound energy transduced along the soft tissue. The follow-up studies lasted 24 months and were performed combining clinical and imaging data.ResultsMean age of the children was 13.8 years. The clinical outcome showed a primary success of 97%. One case alone was submitted to repeat treatment because the first one failed (secondary success). No major or minor complications were recorded. During the investigation time, no relapse of symptomatology or delayed complications were observed.ConclusionAlthough our study is preliminary and limited by a low number of patients, our data show that MRgFUS is effective. This suggests that it might be useful as the first-line treatment in paediatric patients with osteoid osteoma.
22 schema:genre article
23 schema:inLanguage en
24 schema:isAccessibleForFree false
25 schema:isPartOf N875b1d6f2a6049e6a59a28b672c41ece
26 N91521cf5402347cdbe4ce54aeec77a73
27 sg:journal.1016713
28 schema:keywords BackgroundOsteoid osteoma
29 CT-guided radiofrequency ablation
30 ConclusionAlthough
31 MRgFUS
32 MethodsWe
33 ObjectiveTo
34 ResultsMean age
35 University Hospital
36 ablation
37 age
38 bone surface
39 cases
40 children
41 clinical outcomes
42 clinical success rate
43 complications
44 current standard treatment
45 data
46 efficacy
47 energy
48 experience
49 first-line treatment
50 focused ultrasound
51 focused ultrasound treatment
52 follow
53 hospital
54 imaging data
55 invasive percutaneous procedures
56 investigation time
57 lesions
58 low number
59 magnetic resonance
60 materials
61 minor complications
62 months
63 multicentre experience
64 musculoskeletal tumors
65 needleless procedure
66 non-spinal osteoid osteoma
67 number
68 osteoid osteoma
69 osteoma
70 outcomes
71 painful musculoskeletal tumour
72 patients
73 pediatric patients
74 percutaneous procedures
75 primary success
76 procedure
77 procedure of ablation
78 radiofrequency ablation
79 rate
80 relapse
81 relapse of symptomatology
82 resonance
83 results
84 safety
85 soft tissue
86 standard treatment
87 study
88 success
89 success rate
90 surface
91 symptomatology
92 thermal ablation
93 time
94 tissue
95 treatment
96 tumors
97 type of procedure
98 types
99 ultrasound
100 ultrasound energy
101 ultrasound treatment
102 years
103 schema:name Magnetic-resonance-guided focused ultrasound treatment of non-spinal osteoid osteoma in children: multicentre experience
104 schema:pagination 1209-1216
105 schema:productId N5e76dd64f9914936a1706e9090d1c476
106 Na2b0462cbc2e47f1bc2ea361d116a64f
107 Nae5b75b5d12341d193bf174b6e5ec0d9
108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1115676270
109 https://doi.org/10.1007/s00247-019-04426-0
110 schema:sdDatePublished 2022-01-01T18:54
111 schema:sdLicense https://scigraph.springernature.com/explorer/license/
112 schema:sdPublisher N8dfedadfdef14203bef3e561bb953f43
113 schema:url https://doi.org/10.1007/s00247-019-04426-0
114 sgo:license sg:explorer/license/
115 sgo:sdDataset articles
116 rdf:type schema:ScholarlyArticle
117 N00c229cc6cfd49db88743156ccc1bfc4 rdf:first sg:person.0703131174.01
118 rdf:rest N4fd1bd98d3234368b0551421464471cc
119 N0e314ed4e18c4c528f3b43fd1b63036d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Female
121 rdf:type schema:DefinedTerm
122 N10b02ee97fa4435aa3e15e0505343ae6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Child
124 rdf:type schema:DefinedTerm
125 N2e7eb60cfce34986a58c5a8349fe30a8 rdf:first sg:person.0723333404.84
126 rdf:rest N89545a9cc7cb41d9a7ec6915b9033a9e
127 N4815a320dd8b48ebb4ea8da252547341 rdf:first sg:person.01236303515.94
128 rdf:rest Na7e964d8eff94fadb85fec680662b30d
129 N4c399d3cae584135a5dc0ba70db1fc04 rdf:first sg:person.0735362216.50
130 rdf:rest Nb41e498a93c9495ebf4d7594ef27cd97
131 N4cb088cd6bfc4c808db3ee01d915b510 rdf:first sg:person.01215554212.39
132 rdf:rest rdf:nil
133 N4fd1bd98d3234368b0551421464471cc rdf:first sg:person.01255360757.86
134 rdf:rest N2e7eb60cfce34986a58c5a8349fe30a8
135 N5e76dd64f9914936a1706e9090d1c476 schema:name doi
136 schema:value 10.1007/s00247-019-04426-0
137 rdf:type schema:PropertyValue
138 N6bc4eafaa8b642b9a7aa5be809e2f424 rdf:first sg:person.0734545107.11
139 rdf:rest N717e8169d8ae496ebd675a6a5819ce1f
140 N717e8169d8ae496ebd675a6a5819ce1f rdf:first sg:person.01234446237.21
141 rdf:rest N885e66ef2acd43798e08e9add34ad84d
142 N823ec8ae564c41f9b0b41f92aa2aeef3 rdf:first sg:person.01161200444.01
143 rdf:rest N9509cb5a847b497eb5c9d7fa4ff1a030
144 N875b1d6f2a6049e6a59a28b672c41ece schema:volumeNumber 49
145 rdf:type schema:PublicationVolume
146 N885e66ef2acd43798e08e9add34ad84d rdf:first sg:person.013062315016.45
147 rdf:rest N4c399d3cae584135a5dc0ba70db1fc04
148 N89545a9cc7cb41d9a7ec6915b9033a9e rdf:first sg:person.01372177461.45
149 rdf:rest Nebf1f0e5fb0647fcada794b593f5fb9f
150 N8dfedadfdef14203bef3e561bb953f43 schema:name Springer Nature - SN SciGraph project
151 rdf:type schema:Organization
152 N91521cf5402347cdbe4ce54aeec77a73 schema:issueNumber 9
153 rdf:type schema:PublicationIssue
154 N9509cb5a847b497eb5c9d7fa4ff1a030 rdf:first sg:person.01351075172.34
155 rdf:rest N4815a320dd8b48ebb4ea8da252547341
156 Na2b0462cbc2e47f1bc2ea361d116a64f schema:name dimensions_id
157 schema:value pub.1115676270
158 rdf:type schema:PropertyValue
159 Na7e964d8eff94fadb85fec680662b30d rdf:first sg:person.0752660313.39
160 rdf:rest N6bc4eafaa8b642b9a7aa5be809e2f424
161 Nae5b75b5d12341d193bf174b6e5ec0d9 schema:name pubmed_id
162 schema:value 31129699
163 rdf:type schema:PropertyValue
164 Nb41e498a93c9495ebf4d7594ef27cd97 rdf:first sg:person.01365667157.76
165 rdf:rest N00c229cc6cfd49db88743156ccc1bfc4
166 Nb8db8aa63a604646abd4f0ab49bc7d45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Bone Neoplasms
168 rdf:type schema:DefinedTerm
169 Nc16fcd00f0894e0184ea60c23229a059 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Humans
171 rdf:type schema:DefinedTerm
172 Nca402a8bdb934890994e588e1b20fe09 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name High-Intensity Focused Ultrasound Ablation
174 rdf:type schema:DefinedTerm
175 Nd452a3aebe5e4465bc831238a80cfee1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Adolescent
177 rdf:type schema:DefinedTerm
178 Ne617fd26afe741e787184d9dbf03abd1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Male
180 rdf:type schema:DefinedTerm
181 Nebf1f0e5fb0647fcada794b593f5fb9f rdf:first sg:person.01250755056.04
182 rdf:rest N4cb088cd6bfc4c808db3ee01d915b510
183 Nf15951cab1d4463abcadd9ed86bbd7c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Osteoma, Osteoid
185 rdf:type schema:DefinedTerm
186 Nf266835d4e46434aaed98d2820559e5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Magnetic Resonance Imaging, Interventional
188 rdf:type schema:DefinedTerm
189 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
190 schema:name Medical and Health Sciences
191 rdf:type schema:DefinedTerm
192 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
193 schema:name Clinical Sciences
194 rdf:type schema:DefinedTerm
195 sg:journal.1016713 schema:issn 0301-0449
196 1432-1998
197 schema:name Pediatric Radiology
198 schema:publisher Springer Nature
199 rdf:type schema:Periodical
200 sg:person.01161200444.01 schema:affiliation grid-institutes:grid.415103.2
201 schema:familyName Arrigoni
202 schema:givenName Francesco
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161200444.01
204 rdf:type schema:Person
205 sg:person.01215554212.39 schema:affiliation grid-institutes:grid.158820.6
206 schema:familyName Masciocchi
207 schema:givenName Carlo
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215554212.39
209 rdf:type schema:Person
210 sg:person.01234446237.21 schema:affiliation grid-institutes:grid.158820.6
211 schema:familyName Bruno
212 schema:givenName Federico
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234446237.21
214 rdf:type schema:Person
215 sg:person.01236303515.94 schema:affiliation grid-institutes:grid.419038.7
216 schema:familyName Bazzocchi
217 schema:givenName Alberto
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236303515.94
219 rdf:type schema:Person
220 sg:person.01250755056.04 schema:affiliation grid-institutes:grid.7841.a
221 schema:familyName Catalano
222 schema:givenName Carlo
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250755056.04
224 rdf:type schema:Person
225 sg:person.01255360757.86 schema:affiliation grid-institutes:grid.417520.5
226 schema:familyName Zoccali
227 schema:givenName Carmine
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255360757.86
229 rdf:type schema:Person
230 sg:person.013062315016.45 schema:affiliation grid-institutes:grid.158820.6
231 schema:familyName Palumbo
232 schema:givenName Pierpaolo
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013062315016.45
234 rdf:type schema:Person
235 sg:person.01351075172.34 schema:affiliation grid-institutes:grid.7841.a
236 schema:familyName Napoli
237 schema:givenName Alessandro
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351075172.34
239 rdf:type schema:Person
240 sg:person.01365667157.76 schema:affiliation grid-institutes:grid.419038.7
241 schema:familyName Mercatelli
242 schema:givenName Daniele
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365667157.76
244 rdf:type schema:Person
245 sg:person.01372177461.45 schema:affiliation grid-institutes:grid.158820.6
246 schema:familyName Barile
247 schema:givenName Antonio
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372177461.45
249 rdf:type schema:Person
250 sg:person.0703131174.01 schema:affiliation grid-institutes:grid.158820.6
251 schema:familyName Gravina
252 schema:givenName Giovanni Luca
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0703131174.01
254 rdf:type schema:Person
255 sg:person.0723333404.84 schema:affiliation grid-institutes:grid.240952.8
256 schema:familyName Ghanouni
257 schema:givenName Pejman
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723333404.84
259 rdf:type schema:Person
260 sg:person.0734545107.11 schema:affiliation grid-institutes:grid.7841.a
261 schema:familyName Scipione
262 schema:givenName Roberto
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734545107.11
264 rdf:type schema:Person
265 sg:person.0735362216.50 schema:affiliation grid-institutes:grid.7841.a
266 schema:familyName Anzidei
267 schema:givenName Michele
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735362216.50
269 rdf:type schema:Person
270 sg:person.0752660313.39 schema:affiliation grid-institutes:grid.415103.2
271 schema:familyName Zugaro
272 schema:givenName Luigi
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752660313.39
274 rdf:type schema:Person
275 sg:pub.10.1007/s00247-005-0032-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1010523694
276 https://doi.org/10.1007/s00247-005-0032-y
277 rdf:type schema:CreativeWork
278 sg:pub.10.1007/s00270-013-0815-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034766544
279 https://doi.org/10.1007/s00270-013-0815-8
280 rdf:type schema:CreativeWork
281 sg:pub.10.1007/s00330-015-4111-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003229122
282 https://doi.org/10.1007/s00330-015-4111-7
283 rdf:type schema:CreativeWork
284 sg:pub.10.1007/s11547-014-0414-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1013490274
285 https://doi.org/10.1007/s11547-014-0414-z
286 rdf:type schema:CreativeWork
287 sg:pub.10.1007/s12032-017-0904-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084033802
288 https://doi.org/10.1007/s12032-017-0904-7
289 rdf:type schema:CreativeWork
290 sg:pub.10.1007/s12032-017-0909-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083912583
291 https://doi.org/10.1007/s12032-017-0909-2
292 rdf:type schema:CreativeWork
293 grid-institutes:grid.158820.6 schema:alternateName Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila Via Giovanni Di Vincenzo, L’Aquila, Italy
294 schema:name Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila Via Giovanni Di Vincenzo, L’Aquila, Italy
295 rdf:type schema:Organization
296 grid-institutes:grid.240952.8 schema:alternateName Department of Radiology, Stanford University Medical Center, Stanford, CA, USA
297 schema:name Department of Radiology, Stanford University Medical Center, Stanford, CA, USA
298 rdf:type schema:Organization
299 grid-institutes:grid.415103.2 schema:alternateName Department of Emergency Radiology, San Salvatore Hospital, via Vetoio, 67100, L’Aquila, Italy
300 schema:name Department of Emergency Radiology, San Salvatore Hospital, via Vetoio, 67100, L’Aquila, Italy
301 rdf:type schema:Organization
302 grid-institutes:grid.417520.5 schema:alternateName Oncological Orthopedics Department, Regina Elena National Cancer Institute, Rome, Italy
303 schema:name Oncological Orthopedics Department, Regina Elena National Cancer Institute, Rome, Italy
304 rdf:type schema:Organization
305 grid-institutes:grid.419038.7 schema:alternateName Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Via G. C. Pupilli 1, 40136, Bologna, Italy
306 schema:name Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Via G. C. Pupilli 1, 40136, Bologna, Italy
307 rdf:type schema:Organization
308 grid-institutes:grid.7841.a schema:alternateName Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy
309 schema:name Department of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy
310 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...