Myocardial delayed-enhancement CT: initial experience in children and young adults View Full Text


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Article Info

DATE

2017-10

AUTHORS

Hyun Woo Goo

ABSTRACT

BACKGROUND: Clinical utility of myocardial delayed enhancement CT has not been reported in children and young adults. OBJECTIVE: To describe initial experience of myocardial delayed enhancement CT regarding image quality, radiation dose and identification of myocardial lesions in children and young adults. MATERIALS AND METHODS: Between August 2013 and November 2016, 29 consecutive children and young adults (median age 16 months) with suspected coronary artery or myocardial abnormality underwent arterial- and delayed-phase cardiac CT at our institution. We measured CT densities in normal myocardium, left ventricular cavity, and arterial and delayed hypo-enhancing and delayed hyperenhancing myocardial lesions. We then compared the extent of delayed hyperenhancing lesions with delayed-enhancement MRI or thallium single-photon emission CT. RESULTS: Normal myocardium and left ventricular cavity showed significantly higher CT numbers on arterial-phase CT than on delayed-phase CT (t-test, P<0.0001). Contrast-to-noise ratios of the arterial and delayed hypo-enhancing and delayed hyperenhancing lesions on CT were 26.7, 17.6 and 18.7, respectively. Delayed-phase CT findings were equivalent to those of delayed-enhancement MRI in all cases (7/7) and to those of thallium single-photon emission CT in 70% (7/10). CONCLUSION: Myocardial delayed-enhancement CT can be added to evaluate myocardial lesions in select children and young adults with suspected coronary artery or myocardial abnormality. More... »

PAGES

1452-1462

References to SciGraph publications

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  • 2011-07. Individualized volume CT dose index determined by cross-sectional area and mean density of the body to achieve uniform image noise of contrast-enhanced pediatric chest CT obtained at variable kV levels and with combined tube current modulation in PEDIATRIC RADIOLOGY
  • 2015-12. Semiautomatic three-dimensional CT ventricular volumetry in patients with congenital heart disease: agreement between two methods with different user interaction in THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
  • 2010-10. Coronary artery visibility in free-breathing young children with congenital heart disease on cardiac 64-slice CT: dual-source ECG-triggered sequential scan vs. single-source non-ECG-synchronized spiral scan in PEDIATRIC RADIOLOGY
  • 2010-12. The culprit lesion and its consequences: combined visualization of the coronary arteries and delayed myocardial enhancement in dual-source CT: a pilot study in EUROPEAN RADIOLOGY
  • 2009-03. Coronary artery anomalies and clinically important anatomy in patients with congenital heart disease: multislice CT findings in PEDIATRIC RADIOLOGY
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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00247-017-3889-7

    DOI

    http://dx.doi.org/10.1007/s00247-017-3889-7

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1085560677

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28534155


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    55 schema:description BACKGROUND: Clinical utility of myocardial delayed enhancement CT has not been reported in children and young adults. OBJECTIVE: To describe initial experience of myocardial delayed enhancement CT regarding image quality, radiation dose and identification of myocardial lesions in children and young adults. MATERIALS AND METHODS: Between August 2013 and November 2016, 29 consecutive children and young adults (median age 16 months) with suspected coronary artery or myocardial abnormality underwent arterial- and delayed-phase cardiac CT at our institution. We measured CT densities in normal myocardium, left ventricular cavity, and arterial and delayed hypo-enhancing and delayed hyperenhancing myocardial lesions. We then compared the extent of delayed hyperenhancing lesions with delayed-enhancement MRI or thallium single-photon emission CT. RESULTS: Normal myocardium and left ventricular cavity showed significantly higher CT numbers on arterial-phase CT than on delayed-phase CT (t-test, P<0.0001). Contrast-to-noise ratios of the arterial and delayed hypo-enhancing and delayed hyperenhancing lesions on CT were 26.7, 17.6 and 18.7, respectively. Delayed-phase CT findings were equivalent to those of delayed-enhancement MRI in all cases (7/7) and to those of thallium single-photon emission CT in 70% (7/10). CONCLUSION: Myocardial delayed-enhancement CT can be added to evaluate myocardial lesions in select children and young adults with suspected coronary artery or myocardial abnormality.
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