Persistent Pulmonary Hypertension and Histologic Chorioamnionitis in Preterm Infants: Controlled Study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-04

AUTHORS

N. Katz, Y. Bar-Or, A. Raucher-Sterrnfeld, A. Tamir, D. Kohelet

ABSTRACT

Persistent pulmonary hypertension (PPHN) of the newborn is one of the most challenging acute disorders of postnatal transition with substantial morbidity and mortality. The aim of the study was to find if there is an association between persistent pulmonary hypertension and histologic chorioamnionitis in preterm infants. 27 preterm infants with echocardiographic evidence of PPHN within the first 3 days of life were eligible for the study. A matched control group of 27 patients was chosen according to gestational age, date of birth, and gender. Data collection included the need for respiratory support, use of nitric oxide oxygen supplementation, duration of rupture of membranes, blood culture, blood count, and C-reactive protein levels at birth and 12 h. Maternal clinical and laboratory data suggesting clinical chorioamnionitis Placentas of both groups were examined. Differences between groups were analyzed using two-tail t test, Kolmogorov-Smirnov test, Chi-square test. No statistically differences were found in all parameters compared between groups, except for a higher number of patients in the PPHN group who were treated by oxygen supplementation. An association was not found between the incidence of HCA and echocardiographic PPHN in preterm infants in the first 3 days of life. More... »

PAGES

705-708

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00246-018-1809-8

DOI

http://dx.doi.org/10.1007/s00246-018-1809-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101082817

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29453682


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