Systematic Literature Review on the Incidence and Prevalence of Heart Failure in Children and Adolescents View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-03

AUTHORS

Robert E. Shaddy, Aneesh Thomas George, Thomas Jaecklin, Eimear Nic Lochlainn, Lalit Thakur, Rumjhum Agrawal, Susan Solar-Yohay, Fabian Chen, Joseph W. Rossano, Thomas Severin, Michael Burch

ABSTRACT

While the epidemiology of adult heart failure has been extensively researched, this systematic review addresses the less well characterized incidence and prevalence of pediatric HF. The search strategy used Cochrane methodology and identified 83 unique studies for inclusion. Studies were categorized according to whether the HF diagnosis was reported as primary (n = 10); associated with other cardiovascular diseases (CVDs) (n = 49); or associated with non-CVDs (n = 24). A narrative synthesis of the evidence is presented. For primary HF, the incidence ranged from 0.87/100,000 (UK and Ireland) to 7.4/100,000 (Taiwan). A prevalence of 83.3/100,000 was reported in one large population-based study from Spain. HF etiology varied across regions with lower respiratory tract infections and severe anemia predominating in lower income countries, and cardiomyopathies and congenital heart disease major causes in higher income countries. Key findings for the other categories included a prevalence of HF associated with cardiomyopathies ranging from 36.1% (Japan) to 79% (US); associated with congenital heart disease from 8% (Norway) to 82.2% (Nigeria); associated with rheumatic heart diseases from 1.5% (Turkey) to 74% (Zimbabwe); associated with renal disorders from 3.8% (India) to 24.1% (Nigeria); and associated with HIV from 1% (US) to 29.3% (Brazil). To our knowledge, this is the first systematic review of the topic and strengthens current knowledge of pediatric HF epidemiology. Although a large body of research was identified, heterogeneity in study design and diagnostic criteria limited the ability to compare regional data. Standardized definitions of pediatric HF are required to facilitate cross-regional comparisons of epidemiological data. More... »

PAGES

1-22

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00246-017-1787-2

DOI

http://dx.doi.org/10.1007/s00246-017-1787-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1099719421

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29260263


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Failure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Incidence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prevalence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Children's Hospital of Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.239546.f", 
          "name": [
            "Children\u2019s Hospital Los Angeles, 4650 Sunset Blvd. MS#126, 90027, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shaddy", 
        "givenName": "Robert E.", 
        "id": "sg:person.01340024275.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340024275.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Novartis (India)", 
          "id": "https://www.grid.ac/institutes/grid.464975.d", 
          "name": [
            "Novartis Healthcare Pvt. Ltd., Hyderabad, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "George", 
        "givenName": "Aneesh Thomas", 
        "id": "sg:person.01361046253.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361046253.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Shire International GmbH, Global Clinical Development, Z\u00e4hlerweg 10, 6300, Zug, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jaecklin", 
        "givenName": "Thomas", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Novartis (Switzerland)", 
          "id": "https://www.grid.ac/institutes/grid.419481.1", 
          "name": [
            "Novartis Pharma AG, Basel, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lochlainn", 
        "givenName": "Eimear Nic", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Novartis (India)", 
          "id": "https://www.grid.ac/institutes/grid.464975.d", 
          "name": [
            "Novartis Healthcare Pvt. Ltd., Hyderabad, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thakur", 
        "givenName": "Lalit", 
        "id": "sg:person.07644365400.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07644365400.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Novartis (India)", 
          "id": "https://www.grid.ac/institutes/grid.464975.d", 
          "name": [
            "Novartis Healthcare Pvt. Ltd., Hyderabad, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Agrawal", 
        "givenName": "Rumjhum", 
        "id": "sg:person.01065353245.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065353245.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Novartis (United States)", 
          "id": "https://www.grid.ac/institutes/grid.418424.f", 
          "name": [
            "Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Solar-Yohay", 
        "givenName": "Susan", 
        "id": "sg:person.01045675533.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045675533.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Novartis (United States)", 
          "id": "https://www.grid.ac/institutes/grid.418424.f", 
          "name": [
            "Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Fabian", 
        "id": "sg:person.012511143557.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012511143557.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Children\u2019s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rossano", 
        "givenName": "Joseph W.", 
        "id": "sg:person.01304646603.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304646603.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Novartis (Switzerland)", 
          "id": "https://www.grid.ac/institutes/grid.419481.1", 
          "name": [
            "Novartis Pharma AG, Basel, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Severin", 
        "givenName": "Thomas", 
        "id": "sg:person.01360035425.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360035425.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Great Ormond Street Hospital", 
          "id": "https://www.grid.ac/institutes/grid.420468.c", 
          "name": [
            "Cardiorespiratory Division, Great Ormond Street Hospital for Children, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Burch", 
        "givenName": "Michael", 
        "id": "sg:person.01307205424.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307205424.50"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1159/000121603", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000109739"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehs104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000908658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1047951104002069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001233136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1047951104002069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001233136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/clc.20262", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001729016"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.vaccine.2010.07.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002005258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s0041-87811999000300004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003548314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.97.13.1246", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003797339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1651-2227.2008.00854.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004842550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.106.671735", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004935382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.athoracsur.2013.01.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005357543"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00246-013-0665-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005444468", 
          "https://doi.org/10.1007/s00246-013-0665-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrcardio.2016.25", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005645110", 
          "https://doi.org/10.1038/nrcardio.2016.25"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ahj.2005.06.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005742702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00431-011-1555-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006131552", 
          "https://doi.org/10.1007/s00431-011-1555-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3923/tcard.2010.18.22", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006616936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-5273(01)00374-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007289878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-5273(12)70011-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008373886"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2004.04.035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010780974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1442-200x.1997.tb03579.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014196568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1179/146532807x220271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015534856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.2009.173195", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016218621"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1047951100008398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017105327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4103/0972-5229.118412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017467354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4103/0972-5229.118412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017467354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4103/0972-5229.118412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017467354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002469910017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017485881", 
          "https://doi.org/10.1007/s002469910017"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.112.104638", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019281982"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.112.104638", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019281982"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00059-013-3955-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020114653", 
          "https://doi.org/10.1007/s00059-013-3955-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1586/14779072.4.1.33", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022079926"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-009-1325-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022318455", 
          "https://doi.org/10.1007/s00467-009-1325-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-009-1325-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022318455", 
          "https://doi.org/10.1007/s00467-009-1325-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-009-1325-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022318455", 
          "https://doi.org/10.1007/s00467-009-1325-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2013.11.059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022360672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.296.15.1867", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023230258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.77.4.342", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023698689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa021737", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025603462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jech.50.1.62", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025732997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jsha.2009.10.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026910415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/pde.12656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028022315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.2009.176644", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028182306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.cj-11-1032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028591787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-010-1541-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029336005", 
          "https://doi.org/10.1007/s00467-010-1541-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-010-1541-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029336005", 
          "https://doi.org/10.1007/s00467-010-1541-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4314/wajm.v22i1.27978", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031211126"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4314/wajm.v22i1.27978", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031211126"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1442-200x.2000.01180.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031238609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.healun.2009.07.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032008203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s0066-782x2005001700002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032174105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijsu.2010.02.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032308193"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12098-015-1752-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032685576", 
          "https://doi.org/10.1007/s12098-015-1752-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.106.621185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033352324"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s0066-782x2008000100003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036457426"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s0066-782x2003000300007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036863255"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mhj.2001.119423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037071637"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5223(96)70129-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037817834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jech.52.6.377", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038147349"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cardfail.2010.04.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039078088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2013.05.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040198753"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1047951115000943", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041382238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ndt/gfr477", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042727754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jpc.12295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044704333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0003-4975(98)00607-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046433222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3345/kjp.2012.55.10.377", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046803987"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cjca.2013.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047843288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijporl.2009.08.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048527602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1532-5415.2010.02755.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049299204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4314/ahs.v13i3.13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049758284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4314/ahs.v13i3.13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049758284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.110.973826", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050080573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mpd.2002.126301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050346323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mpd.2002.126301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050346323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1442-200x.2004.01858.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050524608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12098-009-0050-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050780789", 
          "https://doi.org/10.1007/s12098-009-0050-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12098-009-0050-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050780789", 
          "https://doi.org/10.1007/s12098-009-0050-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/hv.27152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051171542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1047951110000417", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051354570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2006.08.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053511317"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/tropej/fml064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060060494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/tropej/fmr009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060060985"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.104.2.e14", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067820170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.2006-0557", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067825166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/pir.31-1-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067833987"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/or.8.3.611", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071536429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7196/samj.9076", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073645268"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074730353", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075100938", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075181513", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076636823", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077224681", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077250538", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077670882", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077688572", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3238/arztebl.2009.0269", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077917837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078632977", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7196/samj.7898", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079128459"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-03", 
    "datePublishedReg": "2018-03-01", 
    "description": "While the epidemiology of adult heart failure has been extensively researched, this systematic review addresses the less well characterized incidence and prevalence of pediatric HF. The search strategy used Cochrane methodology and identified 83 unique studies for inclusion. Studies were categorized according to whether the HF diagnosis was reported as primary (n\u2009=\u200910); associated with other cardiovascular diseases (CVDs) (n\u2009=\u200949); or associated with non-CVDs (n\u2009=\u200924). A narrative synthesis of the evidence is presented. For primary HF, the incidence ranged from 0.87/100,000 (UK and Ireland) to 7.4/100,000 (Taiwan). A prevalence of 83.3/100,000 was reported in one large population-based study from Spain. HF etiology varied across regions with lower respiratory tract infections and severe anemia predominating in lower income countries, and cardiomyopathies and congenital heart disease major causes in higher income countries. Key findings for the other categories included a prevalence of HF associated with cardiomyopathies ranging from 36.1% (Japan) to 79% (US); associated with congenital heart disease from 8% (Norway) to 82.2% (Nigeria); associated with rheumatic heart diseases from 1.5% (Turkey) to 74% (Zimbabwe); associated with renal disorders from 3.8% (India) to 24.1% (Nigeria); and associated with HIV from 1% (US) to 29.3% (Brazil). To our knowledge, this is the first systematic review of the topic and strengthens current knowledge of pediatric HF epidemiology. Although a large body of research was identified, heterogeneity in study design and diagnostic criteria limited the ability to compare regional data. Standardized definitions of pediatric HF are required to facilitate cross-regional comparisons of epidemiological data.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00246-017-1787-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1091102", 
        "issn": [
          "0172-0643", 
          "1432-1971"
        ], 
        "name": "Pediatric Cardiology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "39"
      }
    ], 
    "name": "Systematic Literature Review on the Incidence and Prevalence of Heart Failure in Children and Adolescents", 
    "pagination": "1-22", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4b44a58a38c1fa0f721013c5b70192cf6bbd4ce80fc36e31065f5a8861608d52"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29260263"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8003849"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00246-017-1787-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1099719421"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00246-017-1787-2", 
      "https://app.dimensions.ai/details/publication/pub.1099719421"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T23:18", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000484.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00246-017-1787-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00246-017-1787-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00246-017-1787-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00246-017-1787-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00246-017-1787-2'


 

This table displays all metadata directly associated to this object as RDF triples.

447 TRIPLES      21 PREDICATES      124 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00246-017-1787-2 schema:about N0b3e7c28682a4ccd9aea5f8e1ab55ccd
2 N0fedf8321cf244778d4e4e4fddf7c07c
3 N23f6f577f28a48f5b2e160f48ce7af85
4 N47cd9e1052504bfb820f9e048ed86954
5 N711049b66f0f481eb9174b2c1f654b81
6 Nbc96c9c56c114249a13e4bc8a6715122
7 Nc944aeb2233b4cf4a0d244df5a0c3e9c
8 Ne03b8ad8cfbf453a81d30e4982618667
9 Nfa9c9f3028f54a37ac58b472d195b2bb
10 anzsrc-for:11
11 anzsrc-for:1117
12 schema:author N59ef17d2949745aa99844e4c9f3a4fbe
13 schema:citation sg:pub.10.1007/s00059-013-3955-3
14 sg:pub.10.1007/s00246-013-0665-9
15 sg:pub.10.1007/s002469910017
16 sg:pub.10.1007/s00431-011-1555-x
17 sg:pub.10.1007/s00467-009-1325-4
18 sg:pub.10.1007/s00467-010-1541-y
19 sg:pub.10.1007/s12098-009-0050-0
20 sg:pub.10.1007/s12098-015-1752-0
21 sg:pub.10.1038/nrcardio.2016.25
22 https://app.dimensions.ai/details/publication/pub.1074730353
23 https://app.dimensions.ai/details/publication/pub.1075100938
24 https://app.dimensions.ai/details/publication/pub.1075181513
25 https://app.dimensions.ai/details/publication/pub.1076636823
26 https://app.dimensions.ai/details/publication/pub.1077224681
27 https://app.dimensions.ai/details/publication/pub.1077250538
28 https://app.dimensions.ai/details/publication/pub.1077670882
29 https://app.dimensions.ai/details/publication/pub.1077688572
30 https://app.dimensions.ai/details/publication/pub.1078632977
31 https://doi.org/10.1001/jama.296.15.1867
32 https://doi.org/10.1002/clc.20262
33 https://doi.org/10.1016/j.ahj.2005.06.012
34 https://doi.org/10.1016/j.athoracsur.2013.01.014
35 https://doi.org/10.1016/j.cardfail.2010.04.004
36 https://doi.org/10.1016/j.cjca.2013.08.008
37 https://doi.org/10.1016/j.ejca.2006.08.005
38 https://doi.org/10.1016/j.healun.2009.07.003
39 https://doi.org/10.1016/j.ijporl.2009.08.003
40 https://doi.org/10.1016/j.ijsu.2010.02.007
41 https://doi.org/10.1016/j.jacc.2004.04.035
42 https://doi.org/10.1016/j.jacc.2013.05.019
43 https://doi.org/10.1016/j.jacc.2013.11.059
44 https://doi.org/10.1016/j.jsha.2009.10.004
45 https://doi.org/10.1016/j.vaccine.2010.07.013
46 https://doi.org/10.1016/s0003-4975(98)00607-9
47 https://doi.org/10.1016/s0022-5223(96)70129-0
48 https://doi.org/10.1016/s0167-5273(01)00374-6
49 https://doi.org/10.1016/s0167-5273(12)70011-6
50 https://doi.org/10.1017/s1047951100008398
51 https://doi.org/10.1017/s1047951104002069
52 https://doi.org/10.1017/s1047951110000417
53 https://doi.org/10.1017/s1047951115000943
54 https://doi.org/10.1046/j.1442-200x.2000.01180.x
55 https://doi.org/10.1046/j.1442-200x.2004.01858.x
56 https://doi.org/10.1056/nejmoa021737
57 https://doi.org/10.1067/mhj.2001.119423
58 https://doi.org/10.1067/mpd.2002.126301
59 https://doi.org/10.1093/eurheartj/ehs104
60 https://doi.org/10.1093/ndt/gfr477
61 https://doi.org/10.1093/tropej/fml064
62 https://doi.org/10.1093/tropej/fmr009
63 https://doi.org/10.1111/j.1442-200x.1997.tb03579.x
64 https://doi.org/10.1111/j.1532-5415.2010.02755.x
65 https://doi.org/10.1111/j.1651-2227.2008.00854.x
66 https://doi.org/10.1111/jpc.12295
67 https://doi.org/10.1111/pde.12656
68 https://doi.org/10.1136/adc.2009.173195
69 https://doi.org/10.1136/adc.2009.176644
70 https://doi.org/10.1136/adc.77.4.342
71 https://doi.org/10.1136/jech.50.1.62
72 https://doi.org/10.1136/jech.52.6.377
73 https://doi.org/10.1159/000121603
74 https://doi.org/10.1161/01.cir.97.13.1246
75 https://doi.org/10.1161/circulationaha.106.621185
76 https://doi.org/10.1161/circulationaha.106.671735
77 https://doi.org/10.1161/circulationaha.110.973826
78 https://doi.org/10.1161/circulationaha.112.104638
79 https://doi.org/10.1179/146532807x220271
80 https://doi.org/10.1253/circj.cj-11-1032
81 https://doi.org/10.1542/peds.104.2.e14
82 https://doi.org/10.1542/peds.2006-0557
83 https://doi.org/10.1542/pir.31-1-4
84 https://doi.org/10.1586/14779072.4.1.33
85 https://doi.org/10.1590/s0041-87811999000300004
86 https://doi.org/10.1590/s0066-782x2003000300007
87 https://doi.org/10.1590/s0066-782x2005001700002
88 https://doi.org/10.1590/s0066-782x2008000100003
89 https://doi.org/10.3238/arztebl.2009.0269
90 https://doi.org/10.3345/kjp.2012.55.10.377
91 https://doi.org/10.3892/or.8.3.611
92 https://doi.org/10.3923/tcard.2010.18.22
93 https://doi.org/10.4103/0972-5229.118412
94 https://doi.org/10.4161/hv.27152
95 https://doi.org/10.4314/ahs.v13i3.13
96 https://doi.org/10.4314/wajm.v22i1.27978
97 https://doi.org/10.7196/samj.7898
98 https://doi.org/10.7196/samj.9076
99 schema:datePublished 2018-03
100 schema:datePublishedReg 2018-03-01
101 schema:description While the epidemiology of adult heart failure has been extensively researched, this systematic review addresses the less well characterized incidence and prevalence of pediatric HF. The search strategy used Cochrane methodology and identified 83 unique studies for inclusion. Studies were categorized according to whether the HF diagnosis was reported as primary (n = 10); associated with other cardiovascular diseases (CVDs) (n = 49); or associated with non-CVDs (n = 24). A narrative synthesis of the evidence is presented. For primary HF, the incidence ranged from 0.87/100,000 (UK and Ireland) to 7.4/100,000 (Taiwan). A prevalence of 83.3/100,000 was reported in one large population-based study from Spain. HF etiology varied across regions with lower respiratory tract infections and severe anemia predominating in lower income countries, and cardiomyopathies and congenital heart disease major causes in higher income countries. Key findings for the other categories included a prevalence of HF associated with cardiomyopathies ranging from 36.1% (Japan) to 79% (US); associated with congenital heart disease from 8% (Norway) to 82.2% (Nigeria); associated with rheumatic heart diseases from 1.5% (Turkey) to 74% (Zimbabwe); associated with renal disorders from 3.8% (India) to 24.1% (Nigeria); and associated with HIV from 1% (US) to 29.3% (Brazil). To our knowledge, this is the first systematic review of the topic and strengthens current knowledge of pediatric HF epidemiology. Although a large body of research was identified, heterogeneity in study design and diagnostic criteria limited the ability to compare regional data. Standardized definitions of pediatric HF are required to facilitate cross-regional comparisons of epidemiological data.
102 schema:genre research_article
103 schema:inLanguage en
104 schema:isAccessibleForFree true
105 schema:isPartOf Na36210af2fbe45c283161dd7e14436f1
106 Nd56bd5de73c7497faa837bf3e541fdeb
107 sg:journal.1091102
108 schema:name Systematic Literature Review on the Incidence and Prevalence of Heart Failure in Children and Adolescents
109 schema:pagination 1-22
110 schema:productId N0bf586ccce4843488e9d5889ede8d216
111 N19de31db9a9845e59c8d257ff6a9d427
112 N559c362a4b3f4d7583a04eff49bf32f0
113 N5f3e7109a02140b48b2d473dfaca6208
114 Nb568ec4c600f410d96fdc068773491aa
115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099719421
116 https://doi.org/10.1007/s00246-017-1787-2
117 schema:sdDatePublished 2019-04-10T23:18
118 schema:sdLicense https://scigraph.springernature.com/explorer/license/
119 schema:sdPublisher N8e6fa37eacac472ab376fdd4928e8055
120 schema:url http://link.springer.com/10.1007/s00246-017-1787-2
121 sgo:license sg:explorer/license/
122 sgo:sdDataset articles
123 rdf:type schema:ScholarlyArticle
124 N00cbac59cddc466887157457bd1f75ca rdf:first sg:person.01045675533.74
125 rdf:rest N2b893468f97a42bfaf6bf06da4d2d345
126 N05f7440d229a4d04bce6bbf2763cf55f rdf:first N36ae89888c54408da6117abcaa5655b8
127 rdf:rest N4ced09ad66504f8d82610b23e51c92ca
128 N0b3e7c28682a4ccd9aea5f8e1ab55ccd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Heart Failure
130 rdf:type schema:DefinedTerm
131 N0bf586ccce4843488e9d5889ede8d216 schema:name nlm_unique_id
132 schema:value 8003849
133 rdf:type schema:PropertyValue
134 N0fedf8321cf244778d4e4e4fddf7c07c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Adolescent
136 rdf:type schema:DefinedTerm
137 N19de31db9a9845e59c8d257ff6a9d427 schema:name readcube_id
138 schema:value 4b44a58a38c1fa0f721013c5b70192cf6bbd4ce80fc36e31065f5a8861608d52
139 rdf:type schema:PropertyValue
140 N23f6f577f28a48f5b2e160f48ce7af85 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Humans
142 rdf:type schema:DefinedTerm
143 N2b893468f97a42bfaf6bf06da4d2d345 rdf:first sg:person.012511143557.61
144 rdf:rest N34107127883f4291a62d62e5e5d6a154
145 N316b31ab24594afabbb6ad05bf5ed26c rdf:first sg:person.01065353245.86
146 rdf:rest N00cbac59cddc466887157457bd1f75ca
147 N34107127883f4291a62d62e5e5d6a154 rdf:first sg:person.01304646603.51
148 rdf:rest N561e744132bf498cbe294814e1914836
149 N36ae89888c54408da6117abcaa5655b8 schema:affiliation N610b8ebb8c29465c86cee87a4b0836c2
150 schema:familyName Jaecklin
151 schema:givenName Thomas
152 rdf:type schema:Person
153 N47cd9e1052504bfb820f9e048ed86954 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Prevalence
155 rdf:type schema:DefinedTerm
156 N4ced09ad66504f8d82610b23e51c92ca rdf:first N8ac9a23c9f2e44f9a4241667c06d75fa
157 rdf:rest Nf9750e7b010e428d9a25ab0c06ae027a
158 N559c362a4b3f4d7583a04eff49bf32f0 schema:name dimensions_id
159 schema:value pub.1099719421
160 rdf:type schema:PropertyValue
161 N561e744132bf498cbe294814e1914836 rdf:first sg:person.01360035425.20
162 rdf:rest N950f3f9ed4884fb4b4d8f5d3a5188daa
163 N59ef17d2949745aa99844e4c9f3a4fbe rdf:first sg:person.01340024275.15
164 rdf:rest N65472de35b0c47f38f6a31cf1114563c
165 N5f3e7109a02140b48b2d473dfaca6208 schema:name doi
166 schema:value 10.1007/s00246-017-1787-2
167 rdf:type schema:PropertyValue
168 N610b8ebb8c29465c86cee87a4b0836c2 schema:name Shire International GmbH, Global Clinical Development, Zählerweg 10, 6300, Zug, Switzerland
169 rdf:type schema:Organization
170 N65472de35b0c47f38f6a31cf1114563c rdf:first sg:person.01361046253.86
171 rdf:rest N05f7440d229a4d04bce6bbf2763cf55f
172 N67c56efe11d441a9aacdb22690516305 schema:name Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
173 rdf:type schema:Organization
174 N711049b66f0f481eb9174b2c1f654b81 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Child
176 rdf:type schema:DefinedTerm
177 N8ac9a23c9f2e44f9a4241667c06d75fa schema:affiliation https://www.grid.ac/institutes/grid.419481.1
178 schema:familyName Lochlainn
179 schema:givenName Eimear Nic
180 rdf:type schema:Person
181 N8e6fa37eacac472ab376fdd4928e8055 schema:name Springer Nature - SN SciGraph project
182 rdf:type schema:Organization
183 N950f3f9ed4884fb4b4d8f5d3a5188daa rdf:first sg:person.01307205424.50
184 rdf:rest rdf:nil
185 Na36210af2fbe45c283161dd7e14436f1 schema:volumeNumber 39
186 rdf:type schema:PublicationVolume
187 Nb568ec4c600f410d96fdc068773491aa schema:name pubmed_id
188 schema:value 29260263
189 rdf:type schema:PropertyValue
190 Nbc96c9c56c114249a13e4bc8a6715122 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Incidence
192 rdf:type schema:DefinedTerm
193 Nc944aeb2233b4cf4a0d244df5a0c3e9c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Child, Preschool
195 rdf:type schema:DefinedTerm
196 Nd56bd5de73c7497faa837bf3e541fdeb schema:issueNumber 3
197 rdf:type schema:PublicationIssue
198 Ne03b8ad8cfbf453a81d30e4982618667 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Risk Factors
200 rdf:type schema:DefinedTerm
201 Nf9750e7b010e428d9a25ab0c06ae027a rdf:first sg:person.07644365400.08
202 rdf:rest N316b31ab24594afabbb6ad05bf5ed26c
203 Nfa9c9f3028f54a37ac58b472d195b2bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
204 schema:name Infant
205 rdf:type schema:DefinedTerm
206 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
207 schema:name Medical and Health Sciences
208 rdf:type schema:DefinedTerm
209 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
210 schema:name Public Health and Health Services
211 rdf:type schema:DefinedTerm
212 sg:journal.1091102 schema:issn 0172-0643
213 1432-1971
214 schema:name Pediatric Cardiology
215 rdf:type schema:Periodical
216 sg:person.01045675533.74 schema:affiliation https://www.grid.ac/institutes/grid.418424.f
217 schema:familyName Solar-Yohay
218 schema:givenName Susan
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045675533.74
220 rdf:type schema:Person
221 sg:person.01065353245.86 schema:affiliation https://www.grid.ac/institutes/grid.464975.d
222 schema:familyName Agrawal
223 schema:givenName Rumjhum
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065353245.86
225 rdf:type schema:Person
226 sg:person.012511143557.61 schema:affiliation https://www.grid.ac/institutes/grid.418424.f
227 schema:familyName Chen
228 schema:givenName Fabian
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012511143557.61
230 rdf:type schema:Person
231 sg:person.01304646603.51 schema:affiliation N67c56efe11d441a9aacdb22690516305
232 schema:familyName Rossano
233 schema:givenName Joseph W.
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304646603.51
235 rdf:type schema:Person
236 sg:person.01307205424.50 schema:affiliation https://www.grid.ac/institutes/grid.420468.c
237 schema:familyName Burch
238 schema:givenName Michael
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307205424.50
240 rdf:type schema:Person
241 sg:person.01340024275.15 schema:affiliation https://www.grid.ac/institutes/grid.239546.f
242 schema:familyName Shaddy
243 schema:givenName Robert E.
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340024275.15
245 rdf:type schema:Person
246 sg:person.01360035425.20 schema:affiliation https://www.grid.ac/institutes/grid.419481.1
247 schema:familyName Severin
248 schema:givenName Thomas
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360035425.20
250 rdf:type schema:Person
251 sg:person.01361046253.86 schema:affiliation https://www.grid.ac/institutes/grid.464975.d
252 schema:familyName George
253 schema:givenName Aneesh Thomas
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361046253.86
255 rdf:type schema:Person
256 sg:person.07644365400.08 schema:affiliation https://www.grid.ac/institutes/grid.464975.d
257 schema:familyName Thakur
258 schema:givenName Lalit
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07644365400.08
260 rdf:type schema:Person
261 sg:pub.10.1007/s00059-013-3955-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020114653
262 https://doi.org/10.1007/s00059-013-3955-3
263 rdf:type schema:CreativeWork
264 sg:pub.10.1007/s00246-013-0665-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005444468
265 https://doi.org/10.1007/s00246-013-0665-9
266 rdf:type schema:CreativeWork
267 sg:pub.10.1007/s002469910017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017485881
268 https://doi.org/10.1007/s002469910017
269 rdf:type schema:CreativeWork
270 sg:pub.10.1007/s00431-011-1555-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006131552
271 https://doi.org/10.1007/s00431-011-1555-x
272 rdf:type schema:CreativeWork
273 sg:pub.10.1007/s00467-009-1325-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022318455
274 https://doi.org/10.1007/s00467-009-1325-4
275 rdf:type schema:CreativeWork
276 sg:pub.10.1007/s00467-010-1541-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1029336005
277 https://doi.org/10.1007/s00467-010-1541-y
278 rdf:type schema:CreativeWork
279 sg:pub.10.1007/s12098-009-0050-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050780789
280 https://doi.org/10.1007/s12098-009-0050-0
281 rdf:type schema:CreativeWork
282 sg:pub.10.1007/s12098-015-1752-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032685576
283 https://doi.org/10.1007/s12098-015-1752-0
284 rdf:type schema:CreativeWork
285 sg:pub.10.1038/nrcardio.2016.25 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005645110
286 https://doi.org/10.1038/nrcardio.2016.25
287 rdf:type schema:CreativeWork
288 https://app.dimensions.ai/details/publication/pub.1074730353 schema:CreativeWork
289 https://app.dimensions.ai/details/publication/pub.1075100938 schema:CreativeWork
290 https://app.dimensions.ai/details/publication/pub.1075181513 schema:CreativeWork
291 https://app.dimensions.ai/details/publication/pub.1076636823 schema:CreativeWork
292 https://app.dimensions.ai/details/publication/pub.1077224681 schema:CreativeWork
293 https://app.dimensions.ai/details/publication/pub.1077250538 schema:CreativeWork
294 https://app.dimensions.ai/details/publication/pub.1077670882 schema:CreativeWork
295 https://app.dimensions.ai/details/publication/pub.1077688572 schema:CreativeWork
296 https://app.dimensions.ai/details/publication/pub.1078632977 schema:CreativeWork
297 https://doi.org/10.1001/jama.296.15.1867 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023230258
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1002/clc.20262 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001729016
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1016/j.ahj.2005.06.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005742702
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1016/j.athoracsur.2013.01.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005357543
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1016/j.cardfail.2010.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039078088
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1016/j.cjca.2013.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047843288
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1016/j.ejca.2006.08.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053511317
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1016/j.healun.2009.07.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032008203
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1016/j.ijporl.2009.08.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048527602
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1016/j.ijsu.2010.02.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032308193
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1016/j.jacc.2004.04.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010780974
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1016/j.jacc.2013.05.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040198753
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1016/j.jacc.2013.11.059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022360672
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1016/j.jsha.2009.10.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026910415
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1016/j.vaccine.2010.07.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002005258
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1016/s0003-4975(98)00607-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046433222
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1016/s0022-5223(96)70129-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037817834
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1016/s0167-5273(01)00374-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007289878
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1016/s0167-5273(12)70011-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008373886
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1017/s1047951100008398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017105327
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1017/s1047951104002069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001233136
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1017/s1047951110000417 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051354570
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1017/s1047951115000943 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041382238
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1046/j.1442-200x.2000.01180.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1031238609
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1046/j.1442-200x.2004.01858.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050524608
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1056/nejmoa021737 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025603462
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1067/mhj.2001.119423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037071637
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1067/mpd.2002.126301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050346323
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1093/eurheartj/ehs104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000908658
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1093/ndt/gfr477 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042727754
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1093/tropej/fml064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060060494
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1093/tropej/fmr009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060060985
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1111/j.1442-200x.1997.tb03579.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014196568
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1111/j.1532-5415.2010.02755.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049299204
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1111/j.1651-2227.2008.00854.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004842550
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1111/jpc.12295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044704333
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1111/pde.12656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028022315
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1136/adc.2009.173195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016218621
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1136/adc.2009.176644 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028182306
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1136/adc.77.4.342 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023698689
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1136/jech.50.1.62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025732997
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1136/jech.52.6.377 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038147349
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1159/000121603 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000109739
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1161/01.cir.97.13.1246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003797339
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1161/circulationaha.106.621185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033352324
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1161/circulationaha.106.671735 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004935382
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1161/circulationaha.110.973826 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050080573
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1161/circulationaha.112.104638 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019281982
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1179/146532807x220271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015534856
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1253/circj.cj-11-1032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028591787
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1542/peds.104.2.e14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067820170
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1542/peds.2006-0557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067825166
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1542/pir.31-1-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067833987
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1586/14779072.4.1.33 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022079926
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1590/s0041-87811999000300004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003548314
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1590/s0066-782x2003000300007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036863255
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1590/s0066-782x2005001700002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032174105
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1590/s0066-782x2008000100003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036457426
412 rdf:type schema:CreativeWork
413 https://doi.org/10.3238/arztebl.2009.0269 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077917837
414 rdf:type schema:CreativeWork
415 https://doi.org/10.3345/kjp.2012.55.10.377 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046803987
416 rdf:type schema:CreativeWork
417 https://doi.org/10.3892/or.8.3.611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071536429
418 rdf:type schema:CreativeWork
419 https://doi.org/10.3923/tcard.2010.18.22 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006616936
420 rdf:type schema:CreativeWork
421 https://doi.org/10.4103/0972-5229.118412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017467354
422 rdf:type schema:CreativeWork
423 https://doi.org/10.4161/hv.27152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051171542
424 rdf:type schema:CreativeWork
425 https://doi.org/10.4314/ahs.v13i3.13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049758284
426 rdf:type schema:CreativeWork
427 https://doi.org/10.4314/wajm.v22i1.27978 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031211126
428 rdf:type schema:CreativeWork
429 https://doi.org/10.7196/samj.7898 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079128459
430 rdf:type schema:CreativeWork
431 https://doi.org/10.7196/samj.9076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073645268
432 rdf:type schema:CreativeWork
433 https://www.grid.ac/institutes/grid.239546.f schema:alternateName Children's Hospital of Los Angeles
434 schema:name Children’s Hospital Los Angeles, 4650 Sunset Blvd. MS#126, 90027, Los Angeles, CA, USA
435 rdf:type schema:Organization
436 https://www.grid.ac/institutes/grid.418424.f schema:alternateName Novartis (United States)
437 schema:name Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
438 rdf:type schema:Organization
439 https://www.grid.ac/institutes/grid.419481.1 schema:alternateName Novartis (Switzerland)
440 schema:name Novartis Pharma AG, Basel, Switzerland
441 rdf:type schema:Organization
442 https://www.grid.ac/institutes/grid.420468.c schema:alternateName Great Ormond Street Hospital
443 schema:name Cardiorespiratory Division, Great Ormond Street Hospital for Children, London, UK
444 rdf:type schema:Organization
445 https://www.grid.ac/institutes/grid.464975.d schema:alternateName Novartis (India)
446 schema:name Novartis Healthcare Pvt. Ltd., Hyderabad, India
447 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...