Distribution of Organohalogen and Synthetic Musk Compounds in Breast Adipose Tissue of Breast Cancer Patients in Ulster County, New York, ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-04

AUTHORS

Adela Jing Li, Sheldon M Feldman, Richard K McNally, Kurunthachalam Kannan

ABSTRACT

We determined the concentrations of 98 halogenated organic compounds and synthetic musks in breast fat tissues of 50 breast cancer patients (age range: 34-77 years) collected during 1996-1998 in Ulster County, New York, USA. Polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated biphenyl 153 (PBB-153), polybrominated diphenyl ethers (PBDEs), and synthetic musk compounds (SMCs) were analyzed in breast fat tissues, and 46 analytes were found at a detection frequency of ≥ 65% and at concentrations in the decreasing order of OCPs > PCBs > SMCs > PBDEs > PBB-153. PCBs (median: 323 ng/g wet wt) and dichlorodiphenyltrichloroethanes (DDTs, median: 293 ng/g wet wt) were the major compounds found in breast fat tissues. Among PCB congeners, hexa- and hepta-chlorobiphenyls (60% of total PCBs) were the abundant ones. p,p'-DDE accounted for more than 99% of the total DDT concentrations. The concentrations of SMCs and PBDEs were 1-2 orders of magnitude lower than those of PCBs and DDTs. 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-r-2-benzopyran (median: 33 ng/g wet wt) was the most abundant SMC, whereas BDE-47 (median: 4.5 ng/g wet wt) was the most dominant PBDE congener present in breast tissues. A significant correlation (p < 0.05) between women's age and concentrations of DDTs, chlordanes, hexachlorobenzene and PCBs in breast tissues was found. Concentrations of PCBs, PBDEs, OCPs, and SMCs were not significantly different between malignant and benign tumor cases. This study adds baseline information on target tissue burdens of persistent organic contaminants in breast cancer patients. More... »

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00244-019-00621-0

DOI

http://dx.doi.org/10.1007/s00244-019-00621-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113185160

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30949744


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY, 12201-0509, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Adela Jing", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Montefiore Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.240283.f", 
          "name": [
            "Department of Surgery, Montefiore Medical Center, The University Hospital for the Albert Einstein College of Medicine, New York, NY, 10461-2374, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Feldman", 
        "givenName": "Sheldon M", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Pathology for Kingston Benedictine Hospital, Kingston, NY, 12401, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "McNally", 
        "givenName": "Richard K", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King Abdulaziz University", 
          "id": "https://www.grid.ac/institutes/grid.412125.1", 
          "name": [
            "Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY, 12201-0509, USA. Kurunthachalam.kannan@health.ny.gov.", 
            "Biochemistry Department, Faculty of Science and Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia. Kurunthachalam.kannan@health.ny.gov."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kannan", 
        "givenName": "Kurunthachalam", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1080/10408440802291521", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000826532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2008.09.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006849414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200007133430201", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007171562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2013.02.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007323691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0045-6535(01)00234-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010460589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ecoenv.2014.09.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011188911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2005.06.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014249711"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2005.06.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014249711"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2015.08.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015539205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2015.12.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015805791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2008.08.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016076510"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2011.05.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016800786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chemosphere.2007.09.064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016894331"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2011.10.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019726672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chemosphere.2004.09.069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019955204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1476-069x-13-14", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022404672", 
          "https://doi.org/10.1186/1476-069x-13-14"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00244-002-1254-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023045863", 
          "https://doi.org/10.1007/s00244-002-1254-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chemosphere.2011.10.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026168668"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1289/ehp.1003271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026543567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chemosphere.2005.10.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032992238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chemosphere.2008.02.059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035213572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00244-011-9679-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036963257", 
          "https://doi.org/10.1007/s00244-011-9679-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00244-004-0234-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037477412", 
          "https://doi.org/10.1007/s00244-004-0234-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00244-004-0234-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037477412", 
          "https://doi.org/10.1007/s00244-004-0234-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chemosphere.2005.03.041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038189306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11356-009-0251-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038511680", 
          "https://doi.org/10.1007/s11356-009-0251-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11356-009-0251-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038511680", 
          "https://doi.org/10.1007/s11356-009-0251-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002440010104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040195047", 
          "https://doi.org/10.1007/s002440010104"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2016.08.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040212014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2016.08.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040212014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2007.06.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041466535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envpol.2009.08.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042852842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2010.09.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045725699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2014.04.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046039460"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10661-009-0797-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046675414", 
          "https://doi.org/10.1007/s10661-009-0797-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chemosphere.2006.04.065", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049234103"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2016.02.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051475442"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2016.02.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051475442"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chemosphere.2005.01.064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052495485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.est.6b03783", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055089602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es050399x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055498051"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es050399x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055498051"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es7021363", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055514238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es7021363", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055514238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es903476t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055517286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es903476t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055517286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076806729", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamaoncol.2016.6326", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083523169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.est.6b05162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083860340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2017.04.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084849622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2017.04.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085373743"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12940-017-0269-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085996293", 
          "https://doi.org/10.1186/s12940-017-0269-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12940-017-0269-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085996293", 
          "https://doi.org/10.1186/s12940-017-0269-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2017.08.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091409903"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envint.2017.08.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091425348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2018.06.040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105171239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2018.06.040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105171239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2018.07.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105324530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/caac.21492", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106916204"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-04-04", 
    "datePublishedReg": "2019-04-04", 
    "description": "We determined the concentrations of 98 halogenated organic compounds and synthetic musks in breast fat tissues of 50 breast cancer patients (age range: 34-77\u00a0years) collected during 1996-1998 in Ulster County, New York, USA. Polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated biphenyl 153 (PBB-153), polybrominated diphenyl ethers (PBDEs), and synthetic musk compounds (SMCs) were analyzed in breast fat tissues, and 46 analytes were found at a detection frequency of\u2009\u2265\u200965% and at concentrations in the decreasing order of OCPs\u2009>\u2009PCBs\u2009>\u2009SMCs\u2009>\u2009PBDEs\u2009>\u2009PBB-153. PCBs (median: 323\u00a0ng/g wet wt) and dichlorodiphenyltrichloroethanes (DDTs, median: 293\u00a0ng/g wet wt) were the major compounds found in breast fat tissues. Among PCB congeners, hexa- and hepta-chlorobiphenyls (60% of total PCBs) were the abundant ones. p,p'-DDE accounted for more than 99% of the total DDT concentrations. The concentrations of SMCs and PBDEs were 1-2 orders of magnitude lower than those of PCBs and DDTs. 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-r-2-benzopyran (median: 33\u00a0ng/g wet wt) was the most abundant SMC, whereas BDE-47 (median: 4.5\u00a0ng/g wet wt) was the most dominant PBDE congener present in breast tissues. A significant correlation (p\u2009<\u20090.05) between women's age and concentrations of DDTs, chlordanes, hexachlorobenzene and PCBs in breast tissues was found. Concentrations of PCBs, PBDEs, OCPs, and SMCs were not significantly different between malignant and benign tumor cases. This study adds baseline information on target tissue burdens of persistent organic contaminants in breast cancer patients.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00244-019-00621-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1016396", 
        "issn": [
          "0090-4341", 
          "1432-0703"
        ], 
        "name": "Archives of Environmental Contamination and Toxicology", 
        "type": "Periodical"
      }
    ], 
    "name": "Distribution of Organohalogen and Synthetic Musk Compounds in Breast Adipose Tissue of Breast Cancer Patients in Ulster County, New York, USA.", 
    "productId": [
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30949744"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0357245"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00244-019-00621-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113185160"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00244-019-00621-0", 
      "https://app.dimensions.ai/details/publication/pub.1113185160"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000372_0000000372/records_117112_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00244-019-00621-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00244-019-00621-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00244-019-00621-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00244-019-00621-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00244-019-00621-0'


 

This table displays all metadata directly associated to this object as RDF triples.

237 TRIPLES      20 PREDICATES      73 URIs      16 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00244-019-00621-0 schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author Nb48096ac0355456b867ea7b8fa9b46be
4 schema:citation sg:pub.10.1007/s00244-002-1254-8
5 sg:pub.10.1007/s00244-004-0234-6
6 sg:pub.10.1007/s00244-011-9679-6
7 sg:pub.10.1007/s002440010104
8 sg:pub.10.1007/s10661-009-0797-9
9 sg:pub.10.1007/s11356-009-0251-0
10 sg:pub.10.1186/1476-069x-13-14
11 sg:pub.10.1186/s12940-017-0269-6
12 https://app.dimensions.ai/details/publication/pub.1076806729
13 https://doi.org/10.1001/jamaoncol.2016.6326
14 https://doi.org/10.1016/j.chemosphere.2004.09.069
15 https://doi.org/10.1016/j.chemosphere.2005.01.064
16 https://doi.org/10.1016/j.chemosphere.2005.03.041
17 https://doi.org/10.1016/j.chemosphere.2005.10.006
18 https://doi.org/10.1016/j.chemosphere.2006.04.065
19 https://doi.org/10.1016/j.chemosphere.2007.09.064
20 https://doi.org/10.1016/j.chemosphere.2008.02.059
21 https://doi.org/10.1016/j.chemosphere.2011.10.008
22 https://doi.org/10.1016/j.ecoenv.2014.09.032
23 https://doi.org/10.1016/j.envint.2007.06.006
24 https://doi.org/10.1016/j.envint.2008.08.001
25 https://doi.org/10.1016/j.envint.2008.09.008
26 https://doi.org/10.1016/j.envint.2010.09.001
27 https://doi.org/10.1016/j.envint.2011.05.008
28 https://doi.org/10.1016/j.envint.2013.02.012
29 https://doi.org/10.1016/j.envint.2015.12.022
30 https://doi.org/10.1016/j.envint.2016.02.017
31 https://doi.org/10.1016/j.envint.2016.08.011
32 https://doi.org/10.1016/j.envint.2017.04.002
33 https://doi.org/10.1016/j.envint.2017.08.015
34 https://doi.org/10.1016/j.envint.2017.08.019
35 https://doi.org/10.1016/j.envpol.2009.08.011
36 https://doi.org/10.1016/j.envres.2005.06.006
37 https://doi.org/10.1016/j.envres.2011.10.006
38 https://doi.org/10.1016/j.envres.2014.04.009
39 https://doi.org/10.1016/j.envres.2015.08.020
40 https://doi.org/10.1016/j.envres.2017.04.021
41 https://doi.org/10.1016/j.envres.2018.06.040
42 https://doi.org/10.1016/j.envres.2018.07.009
43 https://doi.org/10.1016/s0045-6535(01)00234-x
44 https://doi.org/10.1021/acs.est.6b03783
45 https://doi.org/10.1021/acs.est.6b05162
46 https://doi.org/10.1021/es050399x
47 https://doi.org/10.1021/es7021363
48 https://doi.org/10.1021/es903476t
49 https://doi.org/10.1056/nejm200007133430201
50 https://doi.org/10.1080/10408440802291521
51 https://doi.org/10.1289/ehp.1003271
52 https://doi.org/10.3322/caac.21492
53 schema:datePublished 2019-04-04
54 schema:datePublishedReg 2019-04-04
55 schema:description We determined the concentrations of 98 halogenated organic compounds and synthetic musks in breast fat tissues of 50 breast cancer patients (age range: 34-77 years) collected during 1996-1998 in Ulster County, New York, USA. Polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated biphenyl 153 (PBB-153), polybrominated diphenyl ethers (PBDEs), and synthetic musk compounds (SMCs) were analyzed in breast fat tissues, and 46 analytes were found at a detection frequency of ≥ 65% and at concentrations in the decreasing order of OCPs > PCBs > SMCs > PBDEs > PBB-153. PCBs (median: 323 ng/g wet wt) and dichlorodiphenyltrichloroethanes (DDTs, median: 293 ng/g wet wt) were the major compounds found in breast fat tissues. Among PCB congeners, hexa- and hepta-chlorobiphenyls (60% of total PCBs) were the abundant ones. p,p'-DDE accounted for more than 99% of the total DDT concentrations. The concentrations of SMCs and PBDEs were 1-2 orders of magnitude lower than those of PCBs and DDTs. 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-r-2-benzopyran (median: 33 ng/g wet wt) was the most abundant SMC, whereas BDE-47 (median: 4.5 ng/g wet wt) was the most dominant PBDE congener present in breast tissues. A significant correlation (p < 0.05) between women's age and concentrations of DDTs, chlordanes, hexachlorobenzene and PCBs in breast tissues was found. Concentrations of PCBs, PBDEs, OCPs, and SMCs were not significantly different between malignant and benign tumor cases. This study adds baseline information on target tissue burdens of persistent organic contaminants in breast cancer patients.
56 schema:genre research_article
57 schema:inLanguage en
58 schema:isAccessibleForFree false
59 schema:isPartOf sg:journal.1016396
60 schema:name Distribution of Organohalogen and Synthetic Musk Compounds in Breast Adipose Tissue of Breast Cancer Patients in Ulster County, New York, USA.
61 schema:productId N4be034ad91fa4b6c9e7a39ee72cd888e
62 N9f8fe3eb540540e0a654e7be0a0eb288
63 Nacb1ee6b17ea406aae7987c69ff88dfd
64 Nf07cddb0c6bd4404b6d6e5eda332dbe2
65 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113185160
66 https://doi.org/10.1007/s00244-019-00621-0
67 schema:sdDatePublished 2019-04-11T14:19
68 schema:sdLicense https://scigraph.springernature.com/explorer/license/
69 schema:sdPublisher Naac220b3602f4db5af38aeb47f7291a9
70 schema:url http://link.springer.com/10.1007/s00244-019-00621-0
71 sgo:license sg:explorer/license/
72 sgo:sdDataset articles
73 rdf:type schema:ScholarlyArticle
74 N02d06ee525cd4e8dbce5cc63074e0e16 schema:affiliation https://www.grid.ac/institutes/grid.412125.1
75 schema:familyName Kannan
76 schema:givenName Kurunthachalam
77 rdf:type schema:Person
78 N45a2ee5f82864d82b471522508072724 schema:name Pathology for Kingston Benedictine Hospital, Kingston, NY, 12401, USA.
79 rdf:type schema:Organization
80 N4be034ad91fa4b6c9e7a39ee72cd888e schema:name pubmed_id
81 schema:value 30949744
82 rdf:type schema:PropertyValue
83 N522de277b846462d8ca67b0e881a2a8e schema:affiliation N45a2ee5f82864d82b471522508072724
84 schema:familyName McNally
85 schema:givenName Richard K
86 rdf:type schema:Person
87 N53fcbce45283458c859e0390b2d06cd9 rdf:first N02d06ee525cd4e8dbce5cc63074e0e16
88 rdf:rest rdf:nil
89 N70173bac78de49a3b2788fa1f1eafd3b rdf:first Na8a910cdf6234da7af5fa924c2dfc91f
90 rdf:rest N73a0bf0c5b7d425ca516dd33d543cf5e
91 N73a0bf0c5b7d425ca516dd33d543cf5e rdf:first N522de277b846462d8ca67b0e881a2a8e
92 rdf:rest N53fcbce45283458c859e0390b2d06cd9
93 N73fe860495814994bb00a7d333b4b034 schema:name Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY, 12201-0509, USA.
94 rdf:type schema:Organization
95 N9f8fe3eb540540e0a654e7be0a0eb288 schema:name doi
96 schema:value 10.1007/s00244-019-00621-0
97 rdf:type schema:PropertyValue
98 Na8a910cdf6234da7af5fa924c2dfc91f schema:affiliation https://www.grid.ac/institutes/grid.240283.f
99 schema:familyName Feldman
100 schema:givenName Sheldon M
101 rdf:type schema:Person
102 Naac220b3602f4db5af38aeb47f7291a9 schema:name Springer Nature - SN SciGraph project
103 rdf:type schema:Organization
104 Nacb1ee6b17ea406aae7987c69ff88dfd schema:name nlm_unique_id
105 schema:value 0357245
106 rdf:type schema:PropertyValue
107 Nb48096ac0355456b867ea7b8fa9b46be rdf:first Nb7e85ed93fb7499d88071c917a2ceb16
108 rdf:rest N70173bac78de49a3b2788fa1f1eafd3b
109 Nb7e85ed93fb7499d88071c917a2ceb16 schema:affiliation N73fe860495814994bb00a7d333b4b034
110 schema:familyName Li
111 schema:givenName Adela Jing
112 rdf:type schema:Person
113 Nf07cddb0c6bd4404b6d6e5eda332dbe2 schema:name dimensions_id
114 schema:value pub.1113185160
115 rdf:type schema:PropertyValue
116 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
117 schema:name Medical and Health Sciences
118 rdf:type schema:DefinedTerm
119 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
120 schema:name Oncology and Carcinogenesis
121 rdf:type schema:DefinedTerm
122 sg:journal.1016396 schema:issn 0090-4341
123 1432-0703
124 schema:name Archives of Environmental Contamination and Toxicology
125 rdf:type schema:Periodical
126 sg:pub.10.1007/s00244-002-1254-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023045863
127 https://doi.org/10.1007/s00244-002-1254-8
128 rdf:type schema:CreativeWork
129 sg:pub.10.1007/s00244-004-0234-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037477412
130 https://doi.org/10.1007/s00244-004-0234-6
131 rdf:type schema:CreativeWork
132 sg:pub.10.1007/s00244-011-9679-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036963257
133 https://doi.org/10.1007/s00244-011-9679-6
134 rdf:type schema:CreativeWork
135 sg:pub.10.1007/s002440010104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040195047
136 https://doi.org/10.1007/s002440010104
137 rdf:type schema:CreativeWork
138 sg:pub.10.1007/s10661-009-0797-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046675414
139 https://doi.org/10.1007/s10661-009-0797-9
140 rdf:type schema:CreativeWork
141 sg:pub.10.1007/s11356-009-0251-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038511680
142 https://doi.org/10.1007/s11356-009-0251-0
143 rdf:type schema:CreativeWork
144 sg:pub.10.1186/1476-069x-13-14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022404672
145 https://doi.org/10.1186/1476-069x-13-14
146 rdf:type schema:CreativeWork
147 sg:pub.10.1186/s12940-017-0269-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085996293
148 https://doi.org/10.1186/s12940-017-0269-6
149 rdf:type schema:CreativeWork
150 https://app.dimensions.ai/details/publication/pub.1076806729 schema:CreativeWork
151 https://doi.org/10.1001/jamaoncol.2016.6326 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083523169
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1016/j.chemosphere.2004.09.069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019955204
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/j.chemosphere.2005.01.064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052495485
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/j.chemosphere.2005.03.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038189306
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/j.chemosphere.2005.10.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032992238
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/j.chemosphere.2006.04.065 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049234103
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1016/j.chemosphere.2007.09.064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016894331
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1016/j.chemosphere.2008.02.059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035213572
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1016/j.chemosphere.2011.10.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026168668
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/j.ecoenv.2014.09.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011188911
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/j.envint.2007.06.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041466535
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/j.envint.2008.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016076510
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/j.envint.2008.09.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006849414
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/j.envint.2010.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045725699
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1016/j.envint.2011.05.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016800786
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1016/j.envint.2013.02.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007323691
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/j.envint.2015.12.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015805791
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1016/j.envint.2016.02.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051475442
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1016/j.envint.2016.08.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040212014
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/j.envint.2017.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084849622
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/j.envint.2017.08.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091409903
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/j.envint.2017.08.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091425348
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/j.envpol.2009.08.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042852842
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/j.envres.2005.06.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014249711
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/j.envres.2011.10.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019726672
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/j.envres.2014.04.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046039460
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/j.envres.2015.08.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015539205
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1016/j.envres.2017.04.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085373743
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1016/j.envres.2018.06.040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105171239
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/j.envres.2018.07.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105324530
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1016/s0045-6535(01)00234-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010460589
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1021/acs.est.6b03783 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055089602
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1021/acs.est.6b05162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083860340
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1021/es050399x schema:sameAs https://app.dimensions.ai/details/publication/pub.1055498051
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1021/es7021363 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055514238
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1021/es903476t schema:sameAs https://app.dimensions.ai/details/publication/pub.1055517286
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1056/nejm200007133430201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007171562
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1080/10408440802291521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000826532
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1289/ehp.1003271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026543567
228 rdf:type schema:CreativeWork
229 https://doi.org/10.3322/caac.21492 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106916204
230 rdf:type schema:CreativeWork
231 https://www.grid.ac/institutes/grid.240283.f schema:alternateName Montefiore Medical Center
232 schema:name Department of Surgery, Montefiore Medical Center, The University Hospital for the Albert Einstein College of Medicine, New York, NY, 10461-2374, USA.
233 rdf:type schema:Organization
234 https://www.grid.ac/institutes/grid.412125.1 schema:alternateName King Abdulaziz University
235 schema:name Biochemistry Department, Faculty of Science and Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia. Kurunthachalam.kannan@health.ny.gov.
236 Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY, 12201-0509, USA. Kurunthachalam.kannan@health.ny.gov.
237 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...