High-field, high-resolution, susceptibility-weighted magnetic resonance imaging: improved image quality by addition of contrast agent and higher field strength in patients ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-09-18

AUTHORS

K. Pinker, I. M. Noebauer-Huhmann, I. Stavrou, R. Hoeftberger, P. Szomolanyi, M. Weber, A. Stadlbauer, G. Grabner, E. Knosp, S. Trattnig

ABSTRACT

IntroductionTo demonstrate intratumoral susceptibility effects in malignant brain tumors and to assess visualization of susceptibility effects before and after administration of the paramagnetic contrast agent MultiHance (gadobenate dimeglumine; Bracco Imaging), an agent known to have high relaxivity, with respect to susceptibility effects, image quality, and reduction of scan time.MethodsIncluded in the study were 19 patients with malignant brain tumors who underwent high-resolution, susceptibility-weighted (SW) MR imaging at 3 T before and after administration of contrast agent. In all patients, Multihance was administered intravenously as a bolus (0.1 mmol/kg body weight). MR images were individually evaluated by two radiologists with previous experience in the evaluation of pre- and postcontrast 3-T SW MR images with respect to susceptibility effects, image quality, and reduction of scan time.ResultsIn the 19 patients 21 tumors were diagnosed, of which 18 demonstrated intralesional susceptibility effects both in pre- and postcontrast SW images, and 19 demonstrated contrast enhancement in both SW images and T1-weighted spin-echo MR images. Conspicuity of susceptibility effects and image quality were improved in postcontrast images compared with precontrast images and the scan time was also reduced due to decreased TE values from 9 min (precontrast) to 7 min (postcontrast).ConclusionThe intravenous administration of MultiHance, an agent with high relaxivity, allowed a reduction of scan time from 9 min to 7 min while preserving excellent susceptibility effects and image quality in SW images obtained at 3 T. Contrast enhancement and intralesional susceptibility effects can be assessed in one sequence. More... »

PAGES

9-16

References to SciGraph publications

  • 1998-08. High-resolution venography of the brain using magnetic resonance imaging in MAGNETIC RESONANCE MATERIALS IN PHYSICS, BIOLOGY AND MEDICINE
  • 2001-05. High-resolution blood oxygen-level dependent MR venography (HRBV): a new technique in NEURORADIOLOGY
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    URI

    http://scigraph.springernature.com/pub.10.1007/s00234-007-0298-x

    DOI

    http://dx.doi.org/10.1007/s00234-007-0298-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1017342507

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17876570


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