Destabilizing Giant Vesicles with Electric Fields: An Overview of Current Applications View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-09

AUTHORS

Thomas Portet, Chloé Mauroy, Vincent Démery, Thibault Houles, Jean-Michel Escoffre, David S. Dean, Marie-Pierre Rols

ABSTRACT

This review presents an overview of the effects of electric fields on giant unilamellar vesicles. The application of electrical fields leads to three basic phenomena: shape changes, membrane breakdown, and uptake of molecules. We describe how some of these observations can be used to measure a variety of physical properties of lipid membranes or to advance our understanding of the phenomena of electropermeabilization. We also present results on how electropermeabilization and other liposome responses to applied fields are affected by lipid composition and by the presence of molecules of therapeutic interest in the surrounding solution. More... »

PAGES

555-564

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00232-012-9467-x

DOI

http://dx.doi.org/10.1007/s00232-012-9467-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013338331

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22864479


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