Clinical research in newborn infants: difficulties and specificity View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-05

AUTHORS

Isabelle Ligi, Farid Boubred, Isabelle Grandvuillemin, Umberto Simeoni

ABSTRACT

BACKGROUND: Clinical trials are essential in neonates to evaluate scientifically the efficacy and safety of drugs. However, major specificities condition clinical research in human neonates. OBJECTIVE: To review specific constraints to be taken into account in neonatal research studies. METHODS: A review of the literature and contribution of authors' opinions was carried out. RESULTS AND CONCLUSION: Neonatal specificities that induce obstacles in neonatal studies and proposals are detailed. This review also looks at recommendations recently developed by the European Commission to promote safe and ethical research in neonatology. More... »

PAGES

29-32

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00228-010-0921-3

DOI

http://dx.doi.org/10.1007/s00228-010-0921-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000152145

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21085938


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