Ontology type: schema:ScholarlyArticle
2014-05-11
AUTHORSJohanna Rajasärkkä, Jani Koponen, Riikka Airaksinen, Hannu Kiviranta, Marko Virta
ABSTRACTBioluminescent Saccharomyces cerevisiae yeast-based bioreporters were used to monitor bisphenol A and other estrogenic chemicals in thermal paper samples collected mainly from Finland on two occasions in 2010/2011, and 2013. The bisphenol A-targeted (BPA-R) and the human oestrogen receptor (hERα) bioreporters were applied to analyse both non-treated and extracted paper samples. Bisphenol A was readily bioavailable to the yeast bioreporters on the non-treated paper samples without any pre-treatment. Detected concentrations ranged from a detection limit of 9–142 μg/g to over 20 mg/g of bisphenol A equivalents in the thermal papers. Low bisphenol A like activities were detected in many samples, and were considered to be caused by residual bisphenol A or other types of bisphenols, such as bisphenol S. Most of the thermal paper samples were toxic to the yeast bioreporters. The toxicity did not, however, depend on the bisphenol A concentration of the samples. The yeast bioreporters were demonstrated to be a robust and cost-efficient method to monitor thermal paper samples for their bisphenol A content and estrogenicity. Thermal paper was considered as a potential BPA source for both human exposure and environmental emission. More... »
PAGES5695-5702
http://scigraph.springernature.com/pub.10.1007/s00216-014-7812-x
DOIhttp://dx.doi.org/10.1007/s00216-014-7812-x
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/24817349
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