Recent applications of near-infrared spectroscopy in cancer diagnosis and therapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-01

AUTHORS

Venkata Radhakrishna Kondepati, H. Michael Heise, Juergen Backhaus

ABSTRACT

In recent years, near-infrared spectroscopy (NIRS) has gained importance for non-invasive or minimally invasive diagnostic applications in cancer. This technology is based on differences of endogenous chromophores between cancer and normal tissues using either oxy-haemoglobin or deoxy-haemoglobin, lipid or water bands, or a combination of two or more of these as diagnostic markers. These marker bands provide a basis for the diagnosis and therapy monitoring of several cancers. Various applications also use advances in NIR fluorescence spectroscopy which is based on exogenous contrast-enhancing agents. In this review the literature published during the last seven years has been assessed. It will provide an overview on the importance of the NIRS tools in cancer pathology, and in the near future it is envisaged to play a crucial role in cancer diagnosis, treatment decisions, and defining therapeutic drug levels. More... »

PAGES

125

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00216-007-1651-y

DOI

http://dx.doi.org/10.1007/s00216-007-1651-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040070372

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17955220


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